Page last updated: 2024-10-31

metronidazole and Rupture

metronidazole has been researched along with Rupture in 7 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Rupture: Forcible or traumatic tear or break of an organ or other soft part of the body.

Research Excerpts

ExcerptRelevanceReference
"A study on 42 surgical patients was carried out to find out whether cefuroxime may be substituted for gentamicin in combination with metronidazole in the treatment of peritonitis secondary to perforation of appendix."9.05Comparison of cefuroxime and gentamicin in combination with metronidazole in the treatment of peritonitis due to perforation of the appendix. ( Arvilommi, H; Saario, I; Silvola, H, 1983)
"A study on 42 surgical patients was carried out to find out whether cefuroxime may be substituted for gentamicin in combination with metronidazole in the treatment of peritonitis secondary to perforation of appendix."5.05Comparison of cefuroxime and gentamicin in combination with metronidazole in the treatment of peritonitis due to perforation of the appendix. ( Arvilommi, H; Saario, I; Silvola, H, 1983)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's0 (0.00)18.2507
2000's3 (42.86)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jung, J1
Choi, M1
Kim, YS1
Kwon, H1
Choi, DH1
Tomás, ME1
Pérez Carreras, M1
Morillasa, JD1
Castellano, G1
Solís, JA1
Karantanis, E1
Fynes, MM1
Thum, MY1
Bircher, M1
Stanton, SL1
Saario, I1
Arvilommi, H1
Silvola, H1
Alexander, GR1
Gibson, KT1
Heller, RF1
Gorbach, SL1
Tatooles, CJ1
Loeb, HS1
Rahimtoda, SH1

Trials

1 trial available for metronidazole and Rupture

ArticleYear
Comparison of cefuroxime and gentamicin in combination with metronidazole in the treatment of peritonitis due to perforation of the appendix.
    Acta chirurgica Scandinavica, 1983, Volume: 149, Issue:4

    Topics: Adult; Appendicitis; Bacteria; Cefuroxime; Cephalosporins; Clinical Trials as Topic; Drug Therapy, C

1983

Other Studies

6 other studies available for metronidazole and Rupture

ArticleYear
Nonsurgical resolution of caudal mediastinal paraesophageal abscess in a cat.
    The Journal of veterinary medical science, 2015, Volume: 77, Issue:4

    Topics: Abscess; Amoxicillin-Potassium Clavulanate Combination; Animals; Anti-Bacterial Agents; Cat Diseases

2015
Ruptured pyosalpinx following a fetal reduction procedure.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2012, Volume: 119, Issue:1

    Topics: Abdominal Pain; Adult; Anti-Bacterial Agents; C-Reactive Protein; Cephalosporins; Fallopian Tubes; F

2012
[Rupture of the Achilles' tendon secondary to levofloxacin].
    Gastroenterologia y hepatologia, 2003, Volume: 26, Issue:1

    Topics: Achilles Tendon; Adult; Ceftriaxone; Ciprofloxacin; Crohn Disease; Drug Therapy, Combination; Humans

2003
Symphyseal diastasis and vestibular rupture during spontaneous vaginal delivery.
    BJOG : an international journal of obstetrics and gynaecology, 2003, Volume: 110, Issue:6

    Topics: Adult; Anti-Infective Agents; Cephalosporins; Cephradine; Female; Humans; Metronidazole; Obstetric L

2003
Non-surgical management of rectal tears in two mares.
    Australian veterinary journal, 2002, Volume: 80, Issue:3

    Topics: Animals; Clonixin; Diet; Drug Therapy, Combination; Female; Gentamicins; Horses; Magnesium Sulfate;

2002
Amebic pericarditis.
    JAMA, 1972, May-15, Volume: 220, Issue:7

    Topics: Adult; Amebiasis; Angiocardiography; Biopsy; Cardiac Tamponade; Chloroquine; Emetine; Female; Hemagg

1972