metronidazole has been researched along with Pyoderma in 7 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Pyoderma: Any purulent skin disease (Dorland, 27th ed).
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 4 (57.14) | 18.7374 |
1990's | 2 (28.57) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (14.29) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
DeFelice, T | 1 |
Fung, MA | 1 |
Wu, JJ | 1 |
Beurey, J | 1 |
Canton, P | 1 |
Weber, M | 1 |
Gérard, A | 1 |
Ducommun, F | 1 |
Schooneman, F | 1 |
Janot, C | 1 |
Dureux, JB | 1 |
Sunarwan, I | 1 |
Rosekrans, PC | 1 |
Siragusa, G | 1 |
Aragona, S | 1 |
Guttadauro, G | 1 |
Di Vita, G | 1 |
Di Pace, G | 1 |
Wolfsen, HC | 1 |
Brubacher, LL | 1 |
Ng, CS | 1 |
Kayne, AL | 1 |
Kozarek, RA | 1 |
Mirtschink, S | 1 |
Barth, J | 1 |
Hübner, U | 1 |
McCulloch, AJ | 1 |
McEvoy, A | 1 |
Jackson, JD | 1 |
Jarvis, EH | 1 |
7 other studies available for metronidazole and Pyoderma
Article | Year |
---|---|
A red plaque on the cheek.
Topics: Adult; Benzoyl Peroxide; Cheek; Erythromycin; Female; Granulomatosis, Orofacial; Humans; Metronidazo | 2010 |
[Cervical Pyoderma gangrenosum: treatment by plasma exchanges].
Topics: Adolescent; Crohn Disease; Female; Humans; Metronidazole; Minocycline; Plasma Exchange; Pyoderma; Sk | 1982 |
[Cutaneous amebiases (stimulating pyoderma gangrenosum in ulcerative colitis)].
Topics: Amebiasis; Colitis, Ulcerative; Colostomy; Entamoeba histolytica; Entamoebiasis; Humans; Male; Metro | 1976 |
[Pyoderma gangrenosum and Crohn's disease].
Topics: Adrenal Cortex Hormones; Adult; Crohn Disease; Drug Combinations; Glucosamine; Humans; Male; Metroni | 1990 |
Refractory parastomal ulcers: a multidisciplinary approach.
Topics: Chronic Disease; Colonic Neoplasms; Enterostomy; Female; Humans; Inflammatory Bowel Diseases; Male; | 1990 |
[Case report of the facial pyoderma disease picture].
Topics: Acne Vulgaris; Adult; Facial Dermatoses; Female; Humans; Metronidazole; Pyoderma | 1986 |
Severe steroid responsive pneumonitis associated with pyoderma gangrenosum and ulcerative colitis.
Topics: Ampicillin; Colitis, Ulcerative; Erythromycin; Female; Gentamicins; Humans; Metronidazole; Middle Ag | 1985 |