metronidazole has been researched along with Prostatic Diseases in 6 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Prostatic Diseases: Pathological processes involving the PROSTATE or its component tissues.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Basiri, A | 1 |
| Javaherforooshzadeh, A | 1 |
| Sra, HK | 1 |
| Pastides, P | 1 |
| Lunawat, RP | 1 |
| Maraj, BH | 1 |
| Yang, L | 1 |
| Hu, J | 1 |
| Wei, H | 1 |
| Wang, L | 1 |
| Zhong, H | 1 |
| Summers, JL | 1 |
| Ford, ML | 1 |
| Marberger, H | 1 |
| Decristoforo, A | 1 |
| Swoboda, HP | 1 |
| Goldman, JA | 1 |
1 trial available for metronidazole and Prostatic Diseases
| Article | Year |
|---|---|
[Clinical significance of antibiotic prophylaxis for transrectal prostate biopsy].
Topics: Aged; Aged, 80 and over; Antibiotic Prophylaxis; Biopsy, Needle; Ciprofloxacin; Drug Therapy, Combin | 2001 |
5 other studies available for metronidazole and Prostatic Diseases
| Article | Year |
|---|---|
Percutaneous drainage for treatment of prostate abscess.
Topics: Abscess; Aged; Ceftazidime; Cystostomy; Drainage; Escherichia coli; Escherichia coli Infections; Hum | 2010 |
Prevalence of antimicrobial resistance in intestinal flora of patients undergoing prostatic biopsy: implications for prophylaxis and treatment of infections after biopsy.
Topics: Administration, Oral; Anti-Infective Agents; Antibiotic Prophylaxis; Bacterial Infections; Biopsy, N | 2011 |
The Papanicolaou smear as a diagnostic tool in male trichomoniasis.
Topics: Cytodiagnosis; Genital Diseases, Male; Humans; Male; Methods; Metronidazole; Prostate; Prostatic Dis | 1972 |
[Fertility disorders due to inflammatory male adnexal diseases].
Topics: Abscess; Adult; Fructose; Genital Diseases, Male; Humans; Infertility, Male; Male; Metronidazole; Mi | 1972 |
A comparative study of nitrimidazine and metronidazole in the treatment of trichomonas infections.
Topics: Administration, Oral; Antitrichomonal Agents; Female; Humans; Male; Metronidazole; Morpholines; Nitr | 1974 |