metronidazole has been researched along with Polyps in 3 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Polyps: Discrete abnormal tissue masses that protrude into the lumen of the DIGESTIVE TRACT or the RESPIRATORY TRACT. Polyps can be spheroidal, hemispheroidal, or irregular mound-shaped structures attached to the MUCOUS MEMBRANE of the lumen wall either by a stalk, pedunculus, or by a broad base.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (33.33) | 18.2507 |
2000's | 2 (66.67) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Vakhrushev, IaM | 1 |
Kniazeva, BG | 1 |
Shalom, A | 1 |
Wasserman, I | 1 |
Segal, M | 1 |
Orda, R | 1 |
Pesce, F | 1 |
Barabino, A | 1 |
Dufour, C | 1 |
Caffarena, PE | 1 |
Callea, F | 1 |
Gatti, R | 1 |
1 trial available for metronidazole and Polyps
Article | Year |
---|---|
[Conservative treatment of patients with stomach polyps].
Topics: Adult; Aged; Amoxicillin; Anti-Infective Agents; Drug Therapy, Combination; Female; Gastric Acid; He | 2002 |
2 other studies available for metronidazole and Polyps
Article | Year |
---|---|
Inflammatory fibroid polyp and Helicobacter pylori. Aetiology or coincidence?
Topics: Amoxicillin; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Humans | 2000 |
Hypertrophic gastropathy with transient sessile polyps.
Topics: Animals; Child; Gastric Mucosa; Giardia lamblia; Giardiasis; Humans; Hypertrophy; Male; Metronidazol | 1992 |