Page last updated: 2024-10-31

metronidazole and Polyps

metronidazole has been researched along with Polyps in 3 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Polyps: Discrete abnormal tissue masses that protrude into the lumen of the DIGESTIVE TRACT or the RESPIRATORY TRACT. Polyps can be spheroidal, hemispheroidal, or irregular mound-shaped structures attached to the MUCOUS MEMBRANE of the lumen wall either by a stalk, pedunculus, or by a broad base.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vakhrushev, IaM1
Kniazeva, BG1
Shalom, A1
Wasserman, I1
Segal, M1
Orda, R1
Pesce, F1
Barabino, A1
Dufour, C1
Caffarena, PE1
Callea, F1
Gatti, R1

Trials

1 trial available for metronidazole and Polyps

ArticleYear
[Conservative treatment of patients with stomach polyps].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2002, Issue:4

    Topics: Adult; Aged; Amoxicillin; Anti-Infective Agents; Drug Therapy, Combination; Female; Gastric Acid; He

2002

Other Studies

2 other studies available for metronidazole and Polyps

ArticleYear
Inflammatory fibroid polyp and Helicobacter pylori. Aetiology or coincidence?
    The European journal of surgery = Acta chirurgica, 2000, Volume: 166, Issue:1

    Topics: Amoxicillin; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Humans

2000
Hypertrophic gastropathy with transient sessile polyps.
    Journal of pediatric gastroenterology and nutrition, 1992, Volume: 14, Issue:3

    Topics: Animals; Child; Gastric Mucosa; Giardia lamblia; Giardiasis; Humans; Hypertrophy; Male; Metronidazol

1992