metronidazole has been researched along with Pneumopericardium in 2 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Pneumopericardium: Presence of air or gas in the space between the heart and the PERICARDIUM. The degree of respiratory distress depends on the amount of trapped air and circulation blocked in the systemic and pulmonary veins.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A tension pneumopericardium has to be treated with immediate pericardiocentesis followed by partial pericardiectomy to avoid recurrence." | 1.32 | Tension pneumopericardium caused by positive pressure ventilation complicating anaerobic pneumonia. ( Bleeker-Rovers, CP; Bloemen, TI; Kaasjager, HA; van den Elshout, FJ, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Niakara, A | 1 |
| Bougouma, A | 1 |
| Cisse, R | 1 |
| Bleeker-Rovers, CP | 1 |
| van den Elshout, FJ | 1 |
| Bloemen, TI | 1 |
| Kaasjager, HA | 1 |
2 other studies available for metronidazole and Pneumopericardium
| Article | Year |
|---|---|
[A case of pneumopericardium complicating a liver abscess in a patient infected with HIV].
Topics: Adult; AIDS-Related Opportunistic Infections; Amoxicillin; Anemia; Anti-Infective Agents; Blood Tran | 1999 |
Tension pneumopericardium caused by positive pressure ventilation complicating anaerobic pneumonia.
Topics: Adult; Bacteroides fragilis; Bacteroides Infections; Cardiac Tamponade; Clindamycin; Corynebacterium | 2003 |