metronidazole has been researched along with Pneumonia, Bacterial in 13 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Pneumonia, Bacterial: Inflammation of the lung parenchyma that is caused by bacterial infections.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Drug-related adverse events occurred in 18." | 2.71 | Safety and efficacy of sequential i.v. to p.o. moxifloxacin versus conventional combination therapies for the treatment of community-acquired pneumonia in patients requiring initial i.v. therapy. ( Choudhri, S; Fogarty, CM; Hamed, K; Katz, E; Larsen, LS; Song, J, 2004) |
| "A tension pneumopericardium has to be treated with immediate pericardiocentesis followed by partial pericardiectomy to avoid recurrence." | 1.32 | Tension pneumopericardium caused by positive pressure ventilation complicating anaerobic pneumonia. ( Bleeker-Rovers, CP; Bloemen, TI; Kaasjager, HA; van den Elshout, FJ, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (23.08) | 18.2507 |
| 2000's | 6 (46.15) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Davaus Gasparetto, T | 1 |
| Marchiori, E | 1 |
| Menezes, P | 1 |
| Zanetti, G | 1 |
| Daoud, E | 1 |
| Guzman, J | 1 |
| Le Falher, G | 1 |
| Makinson, A | 1 |
| Eden, A | 1 |
| Lesnik, A | 1 |
| Le Moing, V | 1 |
| Reynes, J | 1 |
| Voillet, F | 1 |
| Charmensat, O | 1 |
| Castanier, M | 1 |
| Roch, A | 1 |
| Papazian, L | 1 |
| Bleeker-Rovers, CP | 1 |
| van den Elshout, FJ | 1 |
| Bloemen, TI | 1 |
| Kaasjager, HA | 1 |
| Levenga, H | 1 |
| Donnelly, P | 1 |
| Blijlevens, N | 1 |
| Verweij, P | 1 |
| Shirango, H | 1 |
| de Pauw, B | 1 |
| Katz, E | 1 |
| Larsen, LS | 1 |
| Fogarty, CM | 1 |
| Hamed, K | 1 |
| Song, J | 1 |
| Choudhri, S | 1 |
| Magid, JH | 1 |
| Iakovlev, SV | 1 |
| Beloborodov, VB | 1 |
| Sidorenko, SV | 1 |
| Iakovlev, VP | 1 |
| Grigor'ev, KB | 1 |
| Eliseeva, EV | 1 |
| Kon, EM | 1 |
| Levit, AL | 1 |
| Kostina, GV | 1 |
| Kuprenkov, AV | 1 |
| Mukhacheva, SIu | 1 |
| Saturnov, AV | 1 |
| Sergeev, IN | 1 |
| Spasov, GP | 1 |
| Stakanov, AV | 1 |
| Ushakova, MA | 1 |
| Dykhuizen, RS | 1 |
| Olson, ES | 1 |
| Clive, S | 1 |
| Douglas, JG | 1 |
| Khan, Z | 1 |
| Coulibaly, G | 1 |
| Touraine, F | 1 |
| Clavel, M | 1 |
| Denis, F | 1 |
| Melloni, B | 1 |
| Bonnaud, F | 1 |
2 reviews available for metronidazole and Pneumonia, Bacterial
| Article | Year |
|---|---|
Fatal hemorrhagic pneumonia caused by infection due to Kytococcus sedentarius--a pathogen or passenger?
Topics: Actinomycetales; Actinomycetales Infections; Acyclovir; Antineoplastic Combined Chemotherapy Protoco | 2004 |
Antibiotics ineffective for prevention of recurrent MI.
Topics: Anti-Bacterial Agents; Azithromycin; Chlamydophila pneumoniae; Humans; Metronidazole; Myocardial Inf | 2004 |
3 trials available for metronidazole and Pneumonia, Bacterial
| Article | Year |
|---|---|
Antibiotics ineffective for prevention of recurrent MI.
Topics: Anti-Bacterial Agents; Azithromycin; Chlamydophila pneumoniae; Humans; Metronidazole; Myocardial Inf | 2004 |
Safety and efficacy of sequential i.v. to p.o. moxifloxacin versus conventional combination therapies for the treatment of community-acquired pneumonia in patients requiring initial i.v. therapy.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Aza Compounds; Azithromycin; Ceftriaxone; Com | 2004 |
[Multicentre study of comparative efficacy of meropenem and combined regimens for empirical antibacterial therapy of severe nosocomial infections: results of clinical and pharmacoeconomic analysis].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminoglycosides; Anti-Bacterial Agents; Anti-Infective A | 2006 |
9 other studies available for metronidazole and Pneumonia, Bacterial
| Article | Year |
|---|---|
Pulmonary toxicity associated with sirolimus following kidney transplantation: computed tomography findings.
Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Bronchoalveolar Lavage Fluid; Diagnosis, Differential; | 2010 |
Q: Are antibiotics indicated for the treatment of aspiration pneumonia?
Topics: Anti-Bacterial Agents; beta-Lactams; Clindamycin; Humans; Metronidazole; Pneumonia; Pneumonia, Aspir | 2010 |
[Two cases of pulmonary gangrene in HIV-infected patients: favorable outcome without surgery].
Topics: Acetamides; Adult; Alcoholism; Amoxicillin; Anti-Bacterial Agents; Drug Therapy, Combination; Gangre | 2011 |
[Porphyromonas causing lung cavitation with empyema].
Topics: Anti-Bacterial Agents; Bacteroidaceae Infections; Bronchoalveolar Lavage Fluid; Humans; Male; Metron | 2012 |
Tension pneumopericardium caused by positive pressure ventilation complicating anaerobic pneumonia.
Topics: Adult; Bacteroides fragilis; Bacteroides Infections; Cardiac Tamponade; Clindamycin; Corynebacterium | 2003 |
Pneumonia and pleuritis in a mare.
Topics: Animals; Anti-Infective Agents; Blood Cell Count; Blood Chemical Analysis; Blood Gas Analysis; Cepha | 2006 |
Necrobacillosis (Lemmiere's syndrome): a rare cause of necrotizing pneumonia.
Topics: Adolescent; Adult; Diagnosis, Differential; Female; Fusobacterium Infections; Fusobacterium necropho | 1994 |
Active management of preterm labour and preterm prelabour rupture of membranes.
Topics: Analgesics; Anti-Bacterial Agents; Embryonic and Fetal Development; Female; Fetal Membranes, Prematu | 1994 |
[Pulmonary infection caused by Fusobacterium nucleatum].
Topics: Anti-Bacterial Agents; Drainage; Follow-Up Studies; Fusobacterium Infections; Fusobacterium nucleatu | 1997 |