metronidazole has been researched along with Pneumococcal Infections in 5 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Pneumococcal Infections: Infections with bacteria of the species STREPTOCOCCUS PNEUMONIAE.
Excerpt | Relevance | Reference |
---|---|---|
"Pneumococcal cellulitis is an uncommon infection." | 1.34 | [Streptococcus pneumoniae cellulitis in a diabetic patient]. ( Bouzat, P; Broux, C; Croizé, J; Jacquot, C; Pavese, P; Soriano, E; Stahl, JP, 2007) |
"The literature on the prevalence of superinfection of pancreatic tissue by S." | 1.32 | Streptococcus pneumoniae as an uncommon cause of superinfected pancreatic pseudocysts. ( Bauerfeind, P; Gubler, C; Ossola, N; Zinkernagel, A, 2003) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 4 (80.00) | 29.6817 |
2010's | 1 (20.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Arrúa, M | 1 |
Samudio, M | 1 |
Fariña, N | 1 |
Cibils, D | 1 |
Laspina, F | 1 |
Sanabria, R | 1 |
Carpinelli, L | 1 |
Mino de Kaspar, H | 1 |
Gubler, C | 1 |
Zinkernagel, A | 1 |
Ossola, N | 1 |
Bauerfeind, P | 1 |
Englert, C | 1 |
Aebert, H | 1 |
Lenhart, M | 1 |
Solleder, A | 1 |
Nerlich, M | 1 |
Neumann, C | 1 |
Peltola, V | 1 |
Svedström, E | 1 |
Waris, M | 1 |
Heikkinen, T | 1 |
Ruuskanen, O | 1 |
Bouzat, P | 1 |
Broux, C | 1 |
Soriano, E | 1 |
Pavese, P | 1 |
Croizé, J | 1 |
Stahl, JP | 1 |
Jacquot, C | 1 |
1 trial available for metronidazole and Pneumococcal Infections
Article | Year |
---|---|
Comparative study of the efficacy of different treatment options in patients with chronic blepharitis.
Topics: Administration, Ophthalmic; Adolescent; Adult; Aged; Aged, 80 and over; Animals; Anti-Bacterial Agen | 2015 |
4 other studies available for metronidazole and Pneumococcal Infections
Article | Year |
---|---|
Streptococcus pneumoniae as an uncommon cause of superinfected pancreatic pseudocysts.
Topics: Amoxicillin; Drug Therapy, Combination; Follow-Up Studies; Humans; Infusions, Intravenous; Male; Met | 2003 |
Thoracic spondylitis from a mycotic (Streptococcus pneumoniae) aortic aneurysm: a case report.
Topics: Aneurysm, Infected; Anti-Bacterial Agents; Aortic Aneurysm, Thoracic; Blood Vessel Prosthesis Implan | 2004 |
Pulmonary abscess of viral-bacterial etiology in a neonate.
Topics: Anti-Infective Agents; Cefuroxime; Cephalexin; Escherichia coli Infections; Female; Humans; Infant, | 2007 |
[Streptococcus pneumoniae cellulitis in a diabetic patient].
Topics: Aged; Ceftriaxone; Cellulitis; Ciprofloxacin; Diabetes Complications; Humans; Male; Metronidazole; M | 2007 |