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metronidazole and Pneumococcal Infections

metronidazole has been researched along with Pneumococcal Infections in 5 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Pneumococcal Infections: Infections with bacteria of the species STREPTOCOCCUS PNEUMONIAE.

Research Excerpts

ExcerptRelevanceReference
"Pneumococcal cellulitis is an uncommon infection."1.34[Streptococcus pneumoniae cellulitis in a diabetic patient]. ( Bouzat, P; Broux, C; Croizé, J; Jacquot, C; Pavese, P; Soriano, E; Stahl, JP, 2007)
"The literature on the prevalence of superinfection of pancreatic tissue by S."1.32Streptococcus pneumoniae as an uncommon cause of superinfected pancreatic pseudocysts. ( Bauerfeind, P; Gubler, C; Ossola, N; Zinkernagel, A, 2003)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (80.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arrúa, M1
Samudio, M1
Fariña, N1
Cibils, D1
Laspina, F1
Sanabria, R1
Carpinelli, L1
Mino de Kaspar, H1
Gubler, C1
Zinkernagel, A1
Ossola, N1
Bauerfeind, P1
Englert, C1
Aebert, H1
Lenhart, M1
Solleder, A1
Nerlich, M1
Neumann, C1
Peltola, V1
Svedström, E1
Waris, M1
Heikkinen, T1
Ruuskanen, O1
Bouzat, P1
Broux, C1
Soriano, E1
Pavese, P1
Croizé, J1
Stahl, JP1
Jacquot, C1

Trials

1 trial available for metronidazole and Pneumococcal Infections

ArticleYear
Comparative study of the efficacy of different treatment options in patients with chronic blepharitis.
    Archivos de la Sociedad Espanola de Oftalmologia, 2015, Volume: 90, Issue:3

    Topics: Administration, Ophthalmic; Adolescent; Adult; Aged; Aged, 80 and over; Animals; Anti-Bacterial Agen

2015

Other Studies

4 other studies available for metronidazole and Pneumococcal Infections

ArticleYear
Streptococcus pneumoniae as an uncommon cause of superinfected pancreatic pseudocysts.
    Infection, 2003, Volume: 31, Issue:4

    Topics: Amoxicillin; Drug Therapy, Combination; Follow-Up Studies; Humans; Infusions, Intravenous; Male; Met

2003
Thoracic spondylitis from a mycotic (Streptococcus pneumoniae) aortic aneurysm: a case report.
    Spine, 2004, Sep-01, Volume: 29, Issue:17

    Topics: Aneurysm, Infected; Anti-Bacterial Agents; Aortic Aneurysm, Thoracic; Blood Vessel Prosthesis Implan

2004
Pulmonary abscess of viral-bacterial etiology in a neonate.
    European journal of pediatrics, 2007, Volume: 166, Issue:12

    Topics: Anti-Infective Agents; Cefuroxime; Cephalexin; Escherichia coli Infections; Female; Humans; Infant,

2007
[Streptococcus pneumoniae cellulitis in a diabetic patient].
    Medecine et maladies infectieuses, 2007, Volume: 37, Issue:5

    Topics: Aged; Ceftriaxone; Cellulitis; Ciprofloxacin; Diabetes Complications; Humans; Male; Metronidazole; M

2007