metronidazole has been researched along with Pleurisy in 7 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Pleurisy: INFLAMMATION of PLEURA, the lining of the LUNG. When PARIETAL PLEURA is involved, there is pleuritic CHEST PAIN.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (42.86) | 18.7374 |
1990's | 1 (14.29) | 18.2507 |
2000's | 3 (42.86) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Stewart, AJ | 1 |
Magid, JH | 1 |
Kibadi, K | 1 |
Dechant, JE | 1 |
MacDonald, DG | 1 |
Crawford, WH | 1 |
O'Connor, BP | 1 |
Piéron, R | 2 |
Debure, A | 1 |
Mafart, Y | 2 |
Lesobre, B | 1 |
Bryskier, A | 1 |
Vergez, P | 1 |
Kolesov, AP | 1 |
Koroliuk, AM | 1 |
Kochetkov, AV | 1 |
Kocherovets, VI | 1 |
Stolbovoĭ, AV | 1 |
Jost, A | 1 |
7 other studies available for metronidazole and Pleurisy
Article | Year |
---|---|
Actinobacillus pleuritis and peritonitis in a quarter horse mare.
Topics: Actinobacillus; Actinobacillus Infections; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, | 2006 |
Pneumonia and pleuritis in a mare.
Topics: Animals; Anti-Infective Agents; Blood Cell Count; Blood Chemical Analysis; Blood Gas Analysis; Cepha | 2006 |
[Mycobacterium ulcerans infection treated by Rifater, pyrazynamide, Myambutol, and surgery: a case report with a 6-year follow-up].
Topics: Anti-Bacterial Agents; Buruli Ulcer; Child; Chloramines; Combined Modality Therapy; Drug Combination | 2008 |
Pleuritis associated with perforation of an isolated oesophageal ulcer in a horse.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Clinical Chemistry Tests; C | 1998 |
[Treatment of purulent anaerobic pleurisy by local injections of metronidazole].
Topics: Bacteroides Infections; Humans; Injections; Male; Metronidazole; Middle Aged; Pleurisy; Suppuration | 1977 |
[Clinical picture, diagnosis and treatment of anaerobic abscess of the lung and pleurisy].
Topics: Adult; Aged; Bacteria, Anaerobic; Chloramphenicol; Combined Modality Therapy; Female; Humans; Lincom | 1985 |
[3 amebic abscesses of the liver of pseudopleuretic form. Recovery after metronidazole without drainage or hepatotomy].
Topics: Adult; Celiac Artery; Humans; Liver Abscess, Amebic; Male; Metronidazole; Pleurisy; Radiography; Rad | 1971 |