metronidazole has been researched along with Pleural Effusion in 18 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Pleural Effusion: Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces. It is a sign of disease and not a diagnosis in itself.
| Excerpt | Relevance | Reference |
|---|---|---|
| "One hundred forty patients with pleuropulmonary amebiasis were classified radiographically in order to rationalize therapy based on the use of metronidazole." | 7.66 | The treatment of pleuropulmonary amebiasis with metronidazole. ( Cameron, EW, 1978) |
| "One hundred forty patients with pleuropulmonary amebiasis were classified radiographically in order to rationalize therapy based on the use of metronidazole." | 3.66 | The treatment of pleuropulmonary amebiasis with metronidazole. ( Cameron, EW, 1978) |
| "The results of treatment of pyothorax using systemic antibiotics, drainage, and lavage of the pleural space, are reported for 9 dogs." | 1.31 | Pyothorax in nine dogs. ( Piek, CJ; Robben, JH, 2000) |
| "Of 33 patients with amoebic liver abscess (ALA) seen over a 5-year period, 24 had intrathoracic complications." | 1.27 | Intrathoracic complications of amoebic liver abscess. ( Aderounmu, A; Adeyemo, AO, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (44.44) | 18.7374 |
| 1990's | 1 (5.56) | 18.2507 |
| 2000's | 4 (22.22) | 29.6817 |
| 2010's | 4 (22.22) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Luque-Paz, D | 1 |
| Verdier, MC | 1 |
| Lefèvre, CR | 1 |
| Chauvin, P | 1 |
| Goter, T | 1 |
| Armange, L | 1 |
| Bayeh, B | 1 |
| Lalanne, S | 1 |
| Tattevin, P | 1 |
| Jouneau, S | 1 |
| Pararajasingam, A | 1 |
| Uwagwu, J | 1 |
| Dong, N | 1 |
| Jin, X | 1 |
| Huang, J | 1 |
| Chen, K | 1 |
| Li, Y | 1 |
| Chen, C | 1 |
| Hu, D | 1 |
| Xie, Y | 1 |
| Anwuzia-Iwegbu, C | 1 |
| Al Omran, Y | 1 |
| Heaford, A | 1 |
| Rao, S | 1 |
| Solaymani-Mohammadi, S | 1 |
| Petri, WA | 1 |
| Parker, SK | 1 |
| Horo, K | 1 |
| N'gom, A | 1 |
| Aké, C | 1 |
| Kouassi, BA | 1 |
| Godé, VC | 1 |
| Ahui, BJ | 1 |
| Fotso, S | 1 |
| Ouattara, K | 1 |
| Kouassi, B | 1 |
| Aka-Danguy, E | 1 |
| Sharifiaghdas, F | 1 |
| Simforoosh, N | 1 |
| Ozhand, A | 1 |
| Johnson, MS | 1 |
| Martin, MW | 1 |
| Adeyemo, AO | 1 |
| Aderounmu, A | 1 |
| Schubert, S | 1 |
| Granz, W | 1 |
| Schenker, U | 1 |
| Schulz, HG | 1 |
| Radosavljevic-Asic, G | 1 |
| Jovanovic, D | 1 |
| Radovanovic, D | 1 |
| Tucakovic, M | 1 |
| Piek, CJ | 1 |
| Robben, JH | 1 |
| Fazlullah, S | 1 |
| Varela, J | 1 |
| Siso, C | 1 |
| Cameron, EW | 1 |
| Maharaj, B | 1 |
| Luvuno, FM | 1 |
| Leary, WP | 1 |
| Pudifin, DJ | 1 |
| Watson, RB | 1 |
| Steel, RK | 1 |
| Spiegel, TM | 1 |
| Henn, RM | 1 |
| Collin, DB | 1 |
18 other studies available for metronidazole and Pleural Effusion
| Article | Year |
|---|---|
Pleural penetration of amoxicillin and metronidazole during pleural infection: An ambispective cohort study.
Topics: Amoxicillin; Anti-Bacterial Agents; Cohort Studies; Communicable Diseases; Female; Humans; Male; Met | 2023 |
Topics: Aged; Anti-Bacterial Agents; Colony Count, Microbial; Drainage; Female; Fluconazole; Humans; Immunoc | 2017 |
Tetratrichomonas in pyopneumothorax.
Topics: Aged, 80 and over; Antiprotozoal Agents; Cilastatin; Empyema, Pleural; Female; Humans; Imipenem; Met | 2019 |
Against all odds. Conservative management of Boerhaave's syndrome.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anti-Bacterial Agents; Antifungal Agents; Drainage; E | 2014 |
Hepatic amebiasis: a reminder of the complications.
Topics: Animals; Antiprotozoal Agents; Diagnosis, Differential; Drainage; Entamoeba histolytica; Genotype; H | 2009 |
[Remarkable evolution of hepatic, pleural and pulmonary amoebiasis: a case report].
Topics: Adult; Animals; Anti-Bacterial Agents; Antiprotozoal Agents; Diagnosis, Differential; Drug Therapy, | 2009 |
A complication after percutaneous nephrolithotomy.
Topics: Abdominal Pain; Adult; Anti-Infective Agents; Ceftriaxone; Constipation; Diagnosis, Differential; Fe | 2010 |
Successful medical treatment of 15 dogs with pyothorax.
Topics: Ampicillin; Animals; Anti-Bacterial Agents; Dog Diseases; Dogs; Drainage; Empyema, Pleural; Female; | 2007 |
Intrathoracic complications of amoebic liver abscess.
Topics: Adolescent; Adult; Central Nervous System Diseases; Child; Drainage; Empyema; Female; Fistula; Human | 1984 |
[Problems of amebic liver abscesses].
Topics: Humans; Immunologic Techniques; Liver Abscess, Amebic; Metronidazole; Pleural Effusion; Recurrence; | 1981 |
Trichomonas in pleural effusion.
Topics: Adult; Bacterial Infections; Empyema, Pleural; Humans; Lung Diseases, Parasitic; Male; Metronidazole | 1994 |
Pyothorax in nine dogs.
Topics: Amoxicillin-Potassium Clavulanate Combination; Animals; Anti-Infective Agents; Dog Diseases; Dogs; D | 2000 |
Pleuro-pulmonary lesions in amebic liver abscess.
Topics: Adult; Drug Therapy, Combination; Emetine; Empyema; Female; Humans; Liver Abscess, Amebic; Metronida | 1978 |
[Eosinophilic pleural effusion during the course of a giardiasis. Report of a case (author's transl)].
Topics: Eosinophils; Giardiasis; Humans; Male; Metronidazole; Middle Aged; Pleural Effusion | 1979 |
The treatment of pleuropulmonary amebiasis with metronidazole.
Topics: Adolescent; Adult; Aged; Amebiasis; Child; Child, Preschool; Empyema; Female; Humans; Lung Diseases; | 1978 |
The conservative management of amoebic liver abscess complicated by thoracic extension.
Topics: Acetaminophen; Adolescent; Adult; Cardiac Tamponade; Drug Therapy, Combination; Humans; Liver Absces | 1987 |
Amebic pericarditis consequent to amebic abscess of right lobe of the liver. Report of a case.
Topics: Amebiasis; Cardiac Tamponade; Chloroquine; Entamoeba histolytica; Humans; Liver Abscess, Amebic; Mal | 1972 |
Amebic abscess of the liver. Treatment failure with metronidazole.
Topics: Administration, Oral; Adult; Chloroquine; Emetine; Humans; Liver Abscess, Amebic; Liver Function Tes | 1973 |