metronidazole has been researched along with Pleural Diseases in 10 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Pleural Diseases: Diseases involving the PLEURA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "One hundred forty patients with pleuropulmonary amebiasis were classified radiographically in order to rationalize therapy based on the use of metronidazole." | 7.66 | The treatment of pleuropulmonary amebiasis with metronidazole. ( Cameron, EW, 1978) |
| "One hundred forty patients with pleuropulmonary amebiasis were classified radiographically in order to rationalize therapy based on the use of metronidazole." | 3.66 | The treatment of pleuropulmonary amebiasis with metronidazole. ( Cameron, EW, 1978) |
| "Metronidazole remains the treatment of choice, and although surgical drainage is contraindicated, percutaneous drainage of abscesses and empyema may occasionally be indicated." | 2.40 | Pleuropulmonary amebiasis. ( Jensen, WA; Lyche, KD, 1997) |
| "We report an unusual presentation of pulmonary embolism (PE) where a 58-year-old man first developed symptoms of community-acquired pneumonia." | 1.48 | An unusual presentation of pulmonary embolism leading to infarction, cavitation, abscess formation and bronchopleural fistulation. ( Banerjee, A; Bennett, L; Morelli, T; Teng, E, 2018) |
| "Treatment with metronidazole (1." | 1.33 | [Amoebic infections of the lung and pleura]. ( Alaoui Yazidi, A; Bahlaoui, A; Bakhatar, A; El Biaze, M; El Meziane, A; Loudadssi, F; Rachid, H; Yassine, N, 2005) |
| "Treatment with metronidazole was effective." | 1.33 | [Trichomonas tenax in pulmonary and pleural diseases]. ( Arnal, JM; Benoit, S; Chiche, L; Chouraki, M; Corno, G; Donati, S; Durand-Gasselin, J; Granier, I, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (50.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Teng, E | 1 |
| Bennett, L | 1 |
| Morelli, T | 1 |
| Banerjee, A | 1 |
| Shrestha, M | 1 |
| Shah, A | 1 |
| Lettieri, C | 1 |
| Rachid, H | 1 |
| Alaoui Yazidi, A | 1 |
| Loudadssi, F | 1 |
| El Biaze, M | 1 |
| Bakhatar, A | 1 |
| Yassine, N | 1 |
| El Meziane, A | 1 |
| Bahlaoui, A | 1 |
| Chiche, L | 1 |
| Donati, S | 1 |
| Corno, G | 1 |
| Benoit, S | 1 |
| Granier, I | 1 |
| Chouraki, M | 1 |
| Arnal, JM | 1 |
| Durand-Gasselin, J | 1 |
| Roudaut, M | 1 |
| Tiendrebeogo, H | 1 |
| Condat, JM | 1 |
| Dezelus, P | 1 |
| Schmidt, D | 1 |
| Li, XY | 1 |
| Lyche, KD | 1 |
| Jensen, WA | 1 |
| Sanders, CV | 1 |
| Hanna, BJ | 1 |
| Lewis, AC | 1 |
| Zhou, ZS | 1 |
| Cameron, EW | 1 |
1 review available for metronidazole and Pleural Diseases
| Article | Year |
|---|---|
Pleuropulmonary amebiasis.
Topics: Animals; Antiprotozoal Agents; Diagnosis, Differential; Drainage; Entamoeba histolytica; Entamoebias | 1997 |
9 other studies available for metronidazole and Pleural Diseases
| Article | Year |
|---|---|
An unusual presentation of pulmonary embolism leading to infarction, cavitation, abscess formation and bronchopleural fistulation.
Topics: Abscess; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Bronchial Fistula; Di | 2018 |
Dyspnea and dysentery: a case report of pleuropulmonary amebiasis.
Topics: Antiprotozoal Agents; Dysentery, Amebic; Dyspnea; Entamoeba histolytica; Entamoebiasis; Humans; Lung | 2010 |
[Amoebic infections of the lung and pleura].
Topics: Adult; Animals; Antiprotozoal Agents; Drainage; Entamoeba histolytica; Entamoebiasis; Humans; Liver | 2005 |
[Trichomonas tenax in pulmonary and pleural diseases].
Topics: Aged, 80 and over; Animals; Antiprotozoal Agents; Humans; Lung Diseases, Parasitic; Male; Metronidaz | 2005 |
[Pleuropulmonary manifestations in amebiasis. Sixty-one cases seen in Abidjan over a three-year period (author's transl)].
Topics: Amebiasis; Cote d'Ivoire; Female; Fluorescent Antibody Technique; Humans; Lung; Lung Diseases, Paras | 1982 |
[Therapeutic effect of metronidazole on anaerobic pulmonary and pleural infections].
Topics: Anaerobiosis; Bacteria; Bacterial Infections; Humans; Lung Diseases; Metronidazole; Pleural Diseases | 1982 |
Metronidazole in the treatment of anaerobic infections.
Topics: Adult; Anaerobiosis; Bacteroides Infections; Female; Humans; Lung Abscess; Male; Metronidazole; Midd | 1979 |
[Observations on treating amebiasis of liver, pleura, and lung with metronidazole (author's transl)].
Topics: Adult; Amebiasis; Female; Humans; Liver Abscess, Amebic; Lung Diseases, Parasitic; Male; Metronidazo | 1979 |
The treatment of pleuropulmonary amebiasis with metronidazole.
Topics: Adolescent; Adult; Aged; Amebiasis; Child; Child, Preschool; Empyema; Female; Humans; Lung Diseases; | 1978 |