metronidazole has been researched along with Placenta, Retained in 2 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Placenta, Retained: A placenta that fails to be expelled after BIRTH of the FETUS. A PLACENTA is retained when the UTERUS fails to contract after the delivery of its content, or when the placenta is abnormally attached to the MYOMETRIUM.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (50.00) | 18.2507 |
2000's | 1 (50.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Halbwax, M | 1 |
Mahamba, CK | 1 |
Ngalula, AM | 1 |
André, C | 1 |
Cohen, RO | 1 |
Colodner, R | 1 |
Ziv, G | 1 |
Keness, J | 1 |
2 other studies available for metronidazole and Placenta, Retained
Article | Year |
---|---|
Placental retention in a bonobo (Pan paniscus).
Topics: Amoxicillin; Animals; Animals, Zoo; Ape Diseases; Female; Metronidazole; Oxytocin; Pan paniscus; Pla | 2009 |
Isolation and antimicrobial susceptibility of obligate anaerobic bacteria recovered from the uteri of dairy cows with retained fetal membranes and postparturient endometritis.
Topics: Animals; Anti-Bacterial Agents; Bacteria, Anaerobic; Cattle; Cattle Diseases; Ciprofloxacin; Clindam | 1996 |