metronidazole has been researched along with Petechiae in 3 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Petechiae: Pinhead size (3 mm) skin discolorization due to hemorrhage.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boyer, M | 1 |
| Sowa, M | 1 |
| Di Meo, I | 1 |
| Eftekharian, S | 1 |
| Steenari, MR | 1 |
| Tiranti, V | 2 |
| Abdenur, JE | 1 |
| Goret, NE | 1 |
| Goret, CC | 1 |
| Zeviani, M | 1 |
2 reviews available for metronidazole and Petechiae
| Article | Year |
|---|---|
Splenic abscess is extremely rare after amoebic dysentery. A case report and review of the literature.
Topics: Abscess; Adult; Amebicides; Anti-Bacterial Agents; Bacteremia; Combined Modality Therapy; Cross Infe | 2019 |
Altered sulfide (H(2)S) metabolism in ethylmalonic encephalopathy.
Topics: Anti-Infective Agents; Brain Diseases, Metabolic, Inborn; Humans; Hydrogen Sulfide; Metronidazole; M | 2013 |
1 other study available for metronidazole and Petechiae
| Article | Year |
|---|---|
Response to medical and a novel dietary treatment in newborn screen identified patients with ethylmalonic encephalopathy.
Topics: Acetylcysteine; Amino Acids; Biomarkers; Brain Diseases, Metabolic, Inborn; Cysteine; Diet; Female; | 2018 |