metronidazole has been researched along with Peritonitis in 112 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Peritonitis: INFLAMMATION of the PERITONEUM lining the ABDOMINAL CAVITY as the result of infectious, autoimmune, or chemical processes. Primary peritonitis is due to infection of the PERITONEAL CAVITY via hematogenous or lymphatic spread and without intra-abdominal source. Secondary peritonitis arises from the ABDOMINAL CAVITY itself through RUPTURE or ABSCESS of intra-abdominal organs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The efficacy of cefepime in the treatment of 46 patients operated for general peritonitis of various genesis and severity (APACHE II not greater than 35) was studied." | 9.09 | [The efficacy of cefepime (Maxipime) in the treatment of abdominal sepsis in surgical patients]. ( Alekseeva, EA; Belotserkovskiĭ, BZ; Gel'fand, BR; Gel'fand, EB; Karabak, VI; Tsedenzhapov, ETs, 1999) |
| "To demonstrate the efficacy of oral metronidazole (OM) in simple or complicated appendicitis with localized peritonitis, a randomized prospective study was carried out in 1083 patients, ranging in age from 4 to 50 years (mean age, 21." | 9.09 | Can oral metronidazole substitute parenteral drug therapy in acute appendicitis? A new policy in the management of simple or complicated appendicitis with localized peritonitis: a randomized controlled clinical trial. ( Banani, SA; Talei, A, 1999) |
| "To evaluate the safety and efficacy of cefepime hydrochloride plus metronidazole vs the combination of imipenem and cilastatin sodium in the treatment of complicated intra-abdominal infections in adult patients." | 9.08 | A randomized, double-blind clinical trial comparing cefepime plus metronidazole with imipenem-cilastatin in the treatment of complicated intra-abdominal infections. Cefepime Intra-abdominal Infection Study Group. ( Barie, PS; Baumgartner, TF; Dellinger, EP; Rotstein, OD; Solomkin, JS; Vogel, SB; Yang, JY, 1997) |
| "Eighty-five patients were randomly allocated to receive either piperacillin (n = 38) or cefuroxime plus metronidazole (n = 45) after surgical treatment of diffuse peritonitis; 78 were evaluable." | 9.07 | Piperacillin compared with cefuroxime plus metronidazole in diffuse peritonitis. ( Alhava, EM; Huttunen, R; Karjalainen, K; Lahtinen, J; Miettinen, P; Paakkonen, M; Silvola, H; Viitanen, J, 1991) |
| "A study on 42 surgical patients was carried out to find out whether cefuroxime may be substituted for gentamicin in combination with metronidazole in the treatment of peritonitis secondary to perforation of appendix." | 9.05 | Comparison of cefuroxime and gentamicin in combination with metronidazole in the treatment of peritonitis due to perforation of the appendix. ( Arvilommi, H; Saario, I; Silvola, H, 1983) |
| "The combination of cefotaxime and metronidazole has been suggested for the treatment of peritonitis." | 9.05 | Short-term antibiotherapy for peritonitis: prospective, randomized trial comparing cefotaxime-metronidazole and clindamycin-tobramycin. ( Béland, L; Biron, S; Bourque, RA; Brochu, G; Marceau, P; Piché, P; Potvin, M, 1984) |
| "The present study aims to evaluate the use of the chlorhexidine gluconate and metronidazole impregnated compresses concerning anastomosis safety in the left colonic anastomosis in the presence of peritonitis." | 8.02 | The effects of sponges soaked with chlorhexidine gluconate and metronidazole on safety of colonic anastomosis in an experimental model of peritonitis. ( Aksoy, N; Aksu, A; Azak Bozan, A; Bozan, MB; Dağlı, AF; Ilhan, N; İlhan, YS; Kanat, BH; Kutluer, N; Türkoğlu, A, 2021) |
| "In a prospective study, 182 consecutive patients were included for the treatment of intraabdominal sepsis with adjuvant metronidazole lavage that was carried out at the end of the operative procedures." | 7.69 | Efficacy of metronidazole lavage in treatment of intraperitoneal sepsis. A prospective study. ( Saha, SK, 1996) |
| "Metronidazole was used for treatment of 212 patients with peritonitis of appendicular origin." | 7.67 | [Metronidazole in the complex treatment of peritonitis of appendicular etiology in children]. ( Astakhov, AA; Kharchenko, DM; Sleptsov, VP; Slezkin, GA, 1987) |
| " The most common treatment-related adverse event was diarrhea (23." | 6.80 | Efficacy and safety of metronidazole injection for the treatment of infectious peritonitis, abdominal abscess and pelvic inflammatory diseases in Japan. ( Matsumizu, M; Mikamo, H; Nagashima, M; Nakazuru, Y, 2015) |
| " We studied the wound infection rate of subcutaneous infiltration of metronidazole (group B) versus irrigation with saline (group A) in patients undergoing exploratory laprotomy for perforation peritonitis with pyoperitoneum." | 5.12 | Wound infection after metronidazole infiltration. ( Bhargava, P; Kumar, A; Mehrotra, N, 2006) |
| "The efficacy of cefepime in the treatment of 46 patients operated for general peritonitis of various genesis and severity (APACHE II not greater than 35) was studied." | 5.09 | [The efficacy of cefepime (Maxipime) in the treatment of abdominal sepsis in surgical patients]. ( Alekseeva, EA; Belotserkovskiĭ, BZ; Gel'fand, BR; Gel'fand, EB; Karabak, VI; Tsedenzhapov, ETs, 1999) |
| "To demonstrate the efficacy of oral metronidazole (OM) in simple or complicated appendicitis with localized peritonitis, a randomized prospective study was carried out in 1083 patients, ranging in age from 4 to 50 years (mean age, 21." | 5.09 | Can oral metronidazole substitute parenteral drug therapy in acute appendicitis? A new policy in the management of simple or complicated appendicitis with localized peritonitis: a randomized controlled clinical trial. ( Banani, SA; Talei, A, 1999) |
| "To evaluate the safety and efficacy of cefepime hydrochloride plus metronidazole vs the combination of imipenem and cilastatin sodium in the treatment of complicated intra-abdominal infections in adult patients." | 5.08 | A randomized, double-blind clinical trial comparing cefepime plus metronidazole with imipenem-cilastatin in the treatment of complicated intra-abdominal infections. Cefepime Intra-abdominal Infection Study Group. ( Barie, PS; Baumgartner, TF; Dellinger, EP; Rotstein, OD; Solomkin, JS; Vogel, SB; Yang, JY, 1997) |
| "Eighty-five patients were randomly allocated to receive either piperacillin (n = 38) or cefuroxime plus metronidazole (n = 45) after surgical treatment of diffuse peritonitis; 78 were evaluable." | 5.07 | Piperacillin compared with cefuroxime plus metronidazole in diffuse peritonitis. ( Alhava, EM; Huttunen, R; Karjalainen, K; Lahtinen, J; Miettinen, P; Paakkonen, M; Silvola, H; Viitanen, J, 1991) |
| " Patients with free purulent peritonitis due to perforated appendicitis or colonic perforation were treated with intravenous infusion of cefuroxime and metronidazole." | 5.06 | A prospective randomized study of continuous peritoneal lavage postoperatively in the treatment of purulent peritonitis. ( Andersson, C; Englund, N; Glise, H; Hallerbäck, B; Nihlberg, A; Solhaug, J; Wahlström, B, 1986) |
| "The combination of cefotaxime and metronidazole has been suggested for the treatment of peritonitis." | 5.05 | Short-term antibiotherapy for peritonitis: prospective, randomized trial comparing cefotaxime-metronidazole and clindamycin-tobramycin. ( Béland, L; Biron, S; Bourque, RA; Brochu, G; Marceau, P; Piché, P; Potvin, M, 1984) |
| "A study on 42 surgical patients was carried out to find out whether cefuroxime may be substituted for gentamicin in combination with metronidazole in the treatment of peritonitis secondary to perforation of appendix." | 5.05 | Comparison of cefuroxime and gentamicin in combination with metronidazole in the treatment of peritonitis due to perforation of the appendix. ( Arvilommi, H; Saario, I; Silvola, H, 1983) |
| "Metronidazole is commonly prescribed for intra-abdominal infections." | 4.02 | Improving metronidazole prescription practices in surgical patients: a full cycle audit. ( Sgrò, A; Wu, DA; Yalamarthi, S, 2021) |
| "The present study aims to evaluate the use of the chlorhexidine gluconate and metronidazole impregnated compresses concerning anastomosis safety in the left colonic anastomosis in the presence of peritonitis." | 4.02 | The effects of sponges soaked with chlorhexidine gluconate and metronidazole on safety of colonic anastomosis in an experimental model of peritonitis. ( Aksoy, N; Aksu, A; Azak Bozan, A; Bozan, MB; Dağlı, AF; Ilhan, N; İlhan, YS; Kanat, BH; Kutluer, N; Türkoğlu, A, 2021) |
| " We believe that the association C3G+aminoglycoside+metronidazole should be used first-line in the pediatric peritonitis in our context." | 3.79 | [Bacteriology of community-acquired peritonitis in children treated in the university hospital of Marrakech]. ( Boutbaoucht, M; Chabaa, L; Mouaffak, Y; Oulad Saiad, M; Salama, T; Soraa, N; Younous, S, 2013) |
| "To explore the effects of metronidazole (Me) on intestinal microcirculation in septic rats, intravital microscopy (IVM) following 16 hours of colon ascendens stent peritonitis (CASP model) was used." | 3.73 | Metronidazole improves intestinal microcirculation in septic rats independently of bacterial burden. ( Bac, VH; Feyerherd, F; Gründling, M; Haase, H; Heidecke, CD; Jünger, M; Lehmann, Ch; Lustig, M; Maier, S; Meissner, K; Pavlovic, D; Usichenko, TI; Wendt, M, 2006) |
| "Based on clinical, bacteriological, and pharmacoeconomic results, ceftriaxone in combination with metronidazole can be regarded as a first-line antimicrobial treatment of secondary peritonitis." | 3.72 | [Prospective comparative observational study on the antibiotic treatment of secondary peritonitis in Germany -- efficacy and cost analysis]. ( Endter, F; Ihle, P; Kullmann, KH; Mittelkötter, U; Reith, HB; Schmitz, R; Thielemann, H, 2003) |
| "Specimens of abdominal adhesions and bowels of rats were examined at light microscopy in treatment of diffuse purulent peritonitis (DPP) by kanamycin and artificial carbomineral sorbent SUMS-2p with metronidazolum or lipoorizinum adsorbed on the surface." | 3.70 | [Structural formation of adhesions in abdominal cavity and bowel walls in treatment of peritonitis by sorbent with absorbed metrinidazole or lipoorizinum (experimental study)]. ( Maĭborodin, IV; Pleshakov, VP; Velichko, IaI, 1999) |
| "In a prospective study, 182 consecutive patients were included for the treatment of intraabdominal sepsis with adjuvant metronidazole lavage that was carried out at the end of the operative procedures." | 3.69 | Efficacy of metronidazole lavage in treatment of intraperitoneal sepsis. A prospective study. ( Saha, SK, 1996) |
| "Metronidazole was used for treatment of 212 patients with peritonitis of appendicular origin." | 3.67 | [Metronidazole in the complex treatment of peritonitis of appendicular etiology in children]. ( Astakhov, AA; Kharchenko, DM; Sleptsov, VP; Slezkin, GA, 1987) |
| "Intravenous metronidazole was administered to a patient with peritonitis caused by a ruptured amebic liver abscess." | 3.66 | Intravenous metronidazole in the treatment of ruptured amebic liver abscess. ( Edmisten, C; Gall, SA; Vernon, RP, 1980) |
| " The most common treatment-related adverse event was diarrhea (23." | 2.80 | Efficacy and safety of metronidazole injection for the treatment of infectious peritonitis, abdominal abscess and pelvic inflammatory diseases in Japan. ( Matsumizu, M; Mikamo, H; Nagashima, M; Nakazuru, Y, 2015) |
| "Moxifloxacin was non-inferior to ceftriaxone/metronidazole in terms of clinical response at test-of-cure in the PP population [clinical cure, 90." | 2.74 | Moxifloxacin is non-inferior to combination therapy with ceftriaxone plus metronidazole in patients with community-origin complicated intra-abdominal infections. ( Chen, MJ; Hampel, B; Ma, EL; Solomkin, J; Zhao, YP, 2009) |
| "Patients were allocated to receive, in addition to ceftriaxone sodium, amikacin sulfate, and metronidazole, molgramostim in a daily dosage of 3 microg/kg for 4 days (group 1) or placebo (group 2)." | 2.72 | Molgramostim (GM-CSF) associated with antibiotic treatment in nontraumatic abdominal sepsis: a randomized, double-blind, placebo-controlled clinical trial. ( Arch, J; González, QH; Hinojosa, C; Medina-Franco, H; Orozco, H; Pantoja, JP; Sifuentes-Osornio, J; Vargas-Vorackova, F; Vilatoba, M, 2006) |
| " Adverse events were reported by 9% of patients in the isepamicin group (16/178) and 10% of patients in the amikacin group (9/89)." | 2.68 | The efficacy and safety of isepamicin compared with amikacin in the treatment of intra-abdominal infections. ( Leal del Rosal, P, 1995) |
| "30 patients had severe acute pelvic inflammatory disease with peritonitis, 3 tubo-ovarian abscesses, 4 endomyometritis, and 2 posthysterectomy pelvic cellulitis." | 2.66 | Sulbactam/ampicillin versus metronidazole/gentamicin in the treatment of severe pelvic infections. ( Crombleholme, W; Dahrouge, D; DeKay, V; Hadley, WK; Landers, D; Ohm-Smith, M; Robbie, MO; Sweet, RL, 1986) |
| "Metronidazole (M) has potent bactericidal activity against anaerobic bacteria." | 2.65 | Prospective, randomized comparison of metronidazole and clindamycin, each with gentamicin, for the treatment of serious intra-abdominal infection. ( , 1983) |
| " Therefore, a correct dosing regimen for the time-dependent molecules (i." | 2.44 | [Pharmacological rationale for choice of antibiotics for intraabdominal infections]. ( Mazzei, T; Novelli, A, 2008) |
| "Fulminant amoebic colitis is very rarely associated with chemotherapy." | 1.35 | Fulminant amoebic colitis during chemotherapy for advanced gastric cancer. ( Ae, T; Hanaoka, N; Higuchi, K; Ishido, K; Koizumi, W; Saigenji, K; Sasaki, T; Tanabe, S, 2009) |
| "Peritonitis was induced via intra-abdominal injection of a faeces and bacteria mixture in male Wistar rats." | 1.35 | Plasminogen activator, but not systemic antibiotic therapy, prevents abscess formation in an experimental model of secondary peritonitis. ( Bleichrodt, RP; Buyne, OR; Hendriks, T; van Goor, H; Verweij, PE, 2008) |
| "metronidazole (MTR) was compared with i." | 1.32 | Results of a prospective, randomized, double blind comparison of the efficacy and the safety of sequential ciprofloxacin (intravenous/oral)+metronidazole (intravenous/oral) with ceftriaxone (intravenous)+metronidazole (intravenous/oral) for the treatment ( Asimakopoulos, C; Bassaris, H; Harlaftis, N; Karravias, D; Kolaras, P; Nikolaidis, P; Skoutelis, A; Starakis, I, 2003) |
| " Male Sprague-Dawley rats were dosed with two doses of metronidazole (50 mg/kg, 12 and 1 h pre-NSAID) or a single 100 mg/kg dose of tempo 1 h prior to NSAIDs." | 1.30 | Pharmacological protection of NSAID-induced intestinal permeability in the rat: effect of tempo and metronidazole as potential free radical scavengers. ( Davies, NM; Jamali, F, 1997) |
| "The postoperative complications were suppuration of the wall (n = 4), intestinal fistula (n = 3), evisceration, and residual abscess." | 1.29 | [Typhoid perforations: experiences in a surgical setting in Cameroon. Apropos of 49 cases]. ( Ibile, A; Malonga, E; Masso-Misse, P; Yao, JG, 1994) |
| "Fulminant transmural amoebic colitis is a rare life-threatening complication of invasive bowel amebiasis." | 1.29 | [Post-partum malignant amebic colitis. Apropos of a case]. ( Andreu, JM; Bourdeix, O; Brissiaud, JC; Diallo, B; Michel, G; Sartelet, H; Vicq, P, 1996) |
| "Once peritonitis is manifest, massive antibiotic therapy must supplement surgical measures." | 1.27 | Surgical aspects in the management of peritonitis. ( Guthy, E, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 49 (43.75) | 18.7374 |
| 1990's | 24 (21.43) | 18.2507 |
| 2000's | 24 (21.43) | 29.6817 |
| 2010's | 11 (9.82) | 24.3611 |
| 2020's | 4 (3.57) | 2.80 |
| Authors | Studies |
|---|---|
| Dos Anjos, MV | 1 |
| Bergoza, L | 1 |
| Fonseca, G | 1 |
| Possa, E | 1 |
| Dos Santos, P | 1 |
| Moura E Silva, S | 1 |
| Tasso, L | 1 |
| Lam, R | 1 |
| Jamidar, PA | 1 |
| Aslanian, HR | 1 |
| Muniraj, T | 1 |
| Aksu, A | 1 |
| Bozan, MB | 1 |
| Kutluer, N | 1 |
| Kanat, BH | 1 |
| İlhan, YS | 1 |
| Türkoğlu, A | 1 |
| Dağlı, AF | 1 |
| Ilhan, N | 1 |
| Azak Bozan, A | 1 |
| Aksoy, N | 1 |
| Sgrò, A | 1 |
| Wu, DA | 1 |
| Yalamarthi, S | 1 |
| Taleb, M | 1 |
| Nardi, N | 1 |
| Arnaud, A | 1 |
| Costet, N | 1 |
| Donnio, PY | 1 |
| Engrand, C | 1 |
| Habonimana, E | 1 |
| Wodey, E | 1 |
| Tattevin, P | 1 |
| Hélias, M | 1 |
| Planchon, J | 1 |
| Bousquet, A | 1 |
| Dubost, C | 1 |
| Obinwa, O | 1 |
| Casidy, M | 1 |
| Flynn, J | 1 |
| Erginel, B | 1 |
| Oksüz, L | 1 |
| Erginel, T | 1 |
| Gün, F | 1 |
| Yanar, F | 1 |
| Gürler, N | 1 |
| Salman, T | 1 |
| Celik, A | 1 |
| Mikamo, H | 1 |
| Matsumizu, M | 1 |
| Nakazuru, Y | 1 |
| Nagashima, M | 1 |
| Liu, J | 1 |
| Fan, P | 1 |
| Chu, J | 1 |
| Yang, J | 1 |
| Yang, X | 1 |
| Zhang, L | 1 |
| Guo, C | 1 |
| Al Rasheed, MR | 1 |
| Senseng, CG | 1 |
| Paladino, JA | 1 |
| Gilliland-Johnson, KK | 1 |
| Adelman, MH | 1 |
| Cohn, SM | 1 |
| Chandra, A | 1 |
| Dhar, P | 1 |
| Dharap, S | 1 |
| Goel, A | 1 |
| Gupta, R | 1 |
| Hardikar, JV | 1 |
| Kapoor, VK | 1 |
| Mathur, AK | 1 |
| Modi, P | 1 |
| Narwaria, M | 1 |
| Ramesh, MK | 1 |
| Ramesh, H | 1 |
| Sastry, RA | 1 |
| Shah, S | 1 |
| Virk, S | 1 |
| Sudheer, OV | 1 |
| Sreevathsa, MR | 1 |
| Varshney, S | 1 |
| Kochhar, P | 1 |
| Somasundaram, S | 1 |
| Desai, C | 1 |
| Schou, M | 1 |
| Buyne, OR | 1 |
| Bleichrodt, RP | 1 |
| van Goor, H | 1 |
| Verweij, PE | 1 |
| Hendriks, T | 1 |
| Rao, S | 1 |
| Solaymani-Mohammadi, S | 1 |
| Petri, WA | 1 |
| Parker, SK | 1 |
| Weiss, G | 1 |
| Reimnitz, P | 1 |
| Hampel, B | 2 |
| Muehlhofer, E | 1 |
| Lippert, H | 1 |
| Hanaoka, N | 1 |
| Higuchi, K | 1 |
| Tanabe, S | 1 |
| Sasaki, T | 1 |
| Ishido, K | 1 |
| Ae, T | 1 |
| Koizumi, W | 1 |
| Saigenji, K | 1 |
| Solomkin, J | 1 |
| Zhao, YP | 1 |
| Ma, EL | 1 |
| Chen, MJ | 1 |
| Lingohr, P | 1 |
| Galetin, T | 1 |
| Rheinwalt, KP | 1 |
| Zalonis, CA | 1 |
| Pillay, A | 1 |
| Secor, W | 1 |
| Humburg, B | 1 |
| Aber, R | 1 |
| Held, M | 1 |
| Mouaffak, Y | 1 |
| Boutbaoucht, M | 1 |
| Soraa, N | 1 |
| Chabaa, L | 1 |
| Salama, T | 1 |
| Oulad Saiad, M | 1 |
| Younous, S | 1 |
| Helenius, I | 1 |
| Takala, T | 1 |
| Ristkari, S | 1 |
| Järvi, K | 1 |
| Mokka, R | 1 |
| Starakis, I | 1 |
| Karravias, D | 1 |
| Asimakopoulos, C | 1 |
| Kolaras, P | 1 |
| Nikolaidis, P | 2 |
| Harlaftis, N | 1 |
| Skoutelis, A | 1 |
| Bassaris, H | 1 |
| Emil, S | 1 |
| Laberge, JM | 1 |
| Mikhail, P | 1 |
| Baican, L | 1 |
| Flageole, H | 1 |
| Nguyen, L | 1 |
| Shaw, K | 1 |
| Mittelkötter, U | 1 |
| Endter, F | 1 |
| Reith, HB | 1 |
| Thielemann, H | 1 |
| Schmitz, R | 1 |
| Ihle, P | 1 |
| Kullmann, KH | 1 |
| Kudara, N | 1 |
| Oana, S | 1 |
| Onodera, K | 1 |
| Ishida, W | 1 |
| Terui, T | 1 |
| Endoh, M | 1 |
| Chiba, T | 1 |
| Inomata, M | 1 |
| Orii, S | 1 |
| Suzuki, K | 1 |
| Deenadayalu, VP | 1 |
| Orinion, EJ | 1 |
| Chalasani, NP | 1 |
| Yoo, HY | 1 |
| Kujath, P | 1 |
| Rauh, V | 1 |
| Weisser, C | 1 |
| Hofmann, G | 1 |
| Bhargava, P | 1 |
| Mehrotra, N | 1 |
| Kumar, A | 1 |
| Orozco, H | 1 |
| Arch, J | 1 |
| Medina-Franco, H | 1 |
| Pantoja, JP | 1 |
| González, QH | 1 |
| Vilatoba, M | 1 |
| Hinojosa, C | 1 |
| Vargas-Vorackova, F | 1 |
| Sifuentes-Osornio, J | 1 |
| Lehmann, Ch | 1 |
| Bac, VH | 1 |
| Pavlovic, D | 1 |
| Lustig, M | 1 |
| Maier, S | 1 |
| Feyerherd, F | 1 |
| Usichenko, TI | 1 |
| Meissner, K | 1 |
| Haase, H | 1 |
| Jünger, M | 1 |
| Wendt, M | 1 |
| Heidecke, CD | 1 |
| Gründling, M | 1 |
| Mogg, TD | 3 |
| Rutherford, DJ | 1 |
| Stewart, AJ | 1 |
| Dykgraaf, S | 1 |
| Hart, J | 1 |
| Wearn, J | 1 |
| Savoie, PH | 1 |
| Peycru, T | 1 |
| Mingoutaud, L | 1 |
| Sow, A | 1 |
| Biance, N | 1 |
| Pauleau, G | 1 |
| Garcia, L | 1 |
| Farthouat, P | 1 |
| Mazzei, T | 1 |
| Novelli, A | 1 |
| Biron, S | 1 |
| Brochu, G | 1 |
| Béland, L | 1 |
| Bourque, RA | 1 |
| Marceau, P | 1 |
| Piché, P | 1 |
| Potvin, M | 1 |
| Smith, JA | 2 |
| Forward, AD | 2 |
| Skidmore, AG | 1 |
| Bell, GA | 2 |
| Murphy, JM | 1 |
| Sutherland, E | 1 |
| Flannigan, GM | 1 |
| Clifford, RP | 1 |
| Carver, RA | 1 |
| Yule, AG | 1 |
| Madden, NP | 1 |
| Saario, I | 1 |
| Arvilommi, H | 1 |
| Silvola, H | 2 |
| McAvinchey, DJ | 1 |
| McCollum, PT | 1 |
| Lynch, G | 1 |
| Ziman, P | 1 |
| Lukes, R | 1 |
| Marcisin, J | 1 |
| Lipcák, P | 1 |
| Benko, A | 1 |
| Stramba, S | 1 |
| Koren, B | 1 |
| Durasko, I | 1 |
| Kosmidis, J | 1 |
| Guthy, E | 1 |
| Tarshis, VE | 2 |
| Bronskaia, LK | 1 |
| Bogomolova, NS | 1 |
| Khromov, IaA | 1 |
| Vogel, F | 1 |
| Stone, HH | 2 |
| Valero de Bernabé, J | 1 |
| García Caballero, J | 1 |
| Herruzo Cabrera, R | 1 |
| Calle Purrón, ME | 1 |
| Rey Calero, J | 1 |
| Gnanaprakasam, D | 1 |
| Sivasubramanian, SV | 1 |
| Rangabashyam, N | 1 |
| Brennan, SS | 1 |
| Smith, GM | 1 |
| Evans, M | 1 |
| Pollock, AV | 1 |
| Fabian, TC | 1 |
| Gall, SA | 1 |
| Edmisten, C | 1 |
| Vernon, RP | 1 |
| Burnett, RJ | 1 |
| Haverstock, DC | 1 |
| Dellinger, EP | 2 |
| Reinhart, HH | 1 |
| Bohnen, JM | 1 |
| Rotstein, OD | 2 |
| Vogel, SB | 2 |
| Solomkin, JS | 2 |
| Wilson, SE | 1 |
| Laing, RB | 1 |
| Wynn, RF | 1 |
| Leen, CL | 1 |
| Stansfield, R | 1 |
| Yao, JG | 1 |
| Masso-Misse, P | 1 |
| Ibile, A | 1 |
| Malonga, E | 1 |
| O'Sullivan, GC | 1 |
| Murphy, D | 1 |
| O'Brien, MG | 1 |
| Ireland, A | 1 |
| Leal del Rosal, P | 1 |
| Saha, SK | 2 |
| Miasnikova, NA | 1 |
| Bourdeix, O | 1 |
| Andreu, JM | 1 |
| Sartelet, H | 1 |
| Diallo, B | 1 |
| Brissiaud, JC | 1 |
| Vicq, P | 1 |
| Michel, G | 1 |
| Davies, NM | 1 |
| Jamali, F | 1 |
| Winkeltau, GJ | 1 |
| Töns, C | 1 |
| Bertram, P | 1 |
| Schumpelick, V | 1 |
| Barie, PS | 1 |
| Yang, JY | 1 |
| Baumgartner, TF | 1 |
| Schölmerich, J | 1 |
| Glück, T | 1 |
| Sitges-Serra, A | 1 |
| Guirao, X | 1 |
| Díaz, J | 1 |
| Azanza, R | 1 |
| Rodríguez Noriega, A | 1 |
| Lizasoaín, M | 1 |
| Jover, JM | 1 |
| Moreno Azcoita, M | 1 |
| Caínzos, M | 1 |
| Maĭborodin, IV | 1 |
| Velichko, IaI | 1 |
| Pleshakov, VP | 1 |
| Banani, SA | 1 |
| Talei, A | 1 |
| McConkey, SJ | 1 |
| McCarthy, ND | 1 |
| Keane, CT | 1 |
| Ohlin, B | 1 |
| Cederberg, A | 1 |
| Forssell, H | 1 |
| Solhaug, JH | 1 |
| Tveit, E | 1 |
| Knoll-Köhler, E | 1 |
| Gel'fand, EB | 1 |
| Belotserkovskiĭ, BZ | 1 |
| Alekseeva, EA | 1 |
| Tsedenzhapov, ETs | 1 |
| Karabak, VI | 1 |
| Gel'fand, BR | 1 |
| Maltezou, HC | 1 |
| Lebesii, E | 1 |
| Dimitriou, L | 1 |
| Androulakakis, E | 1 |
| Kafetzis, DA | 1 |
| Melhus, A | 1 |
| Adams, EB | 2 |
| MacLeod, IN | 2 |
| Nord, CE | 2 |
| Edlund, C | 2 |
| Luke, M | 1 |
| Iversen, J | 1 |
| Søndergaard, J | 1 |
| Kvist, E | 1 |
| Lund, P | 1 |
| Andersen, F | 1 |
| Naver, L | 1 |
| Larsen, PN | 2 |
| Clausen, B | 1 |
| Prag, J | 1 |
| Paakkonen, M | 1 |
| Alhava, EM | 1 |
| Huttunen, R | 1 |
| Karjalainen, K | 1 |
| Lahtinen, J | 1 |
| Miettinen, P | 1 |
| Viitanen, J | 1 |
| Barth, X | 1 |
| Hayoun, H | 1 |
| Rat, P | 1 |
| Hoen, JP | 1 |
| Favre, JP | 1 |
| Lombard-Platet, R | 1 |
| Moesgaard, F | 1 |
| Nielsen, ML | 1 |
| Hjortrup, A | 1 |
| Kjersgaard, P | 1 |
| Sørensen, C | 1 |
| Hoffmann, S | 1 |
| Schmitt, M | 1 |
| Bondonny, JM | 1 |
| Delmas, P | 1 |
| Galifer, RB | 1 |
| Revillon, Y | 1 |
| Robert, M | 1 |
| Janin, A | 1 |
| Karimov, ShI | 1 |
| Babadzhanov, BD | 1 |
| Asrarov, AA | 1 |
| Islamov, MS | 1 |
| Durmanov, BD | 1 |
| Ponomareva, TR | 1 |
| Murphy, J | 1 |
| Forget, JP | 1 |
| Asorey Carballeira, A | 1 |
| Alguacil Muñoz, A | 1 |
| Guerra Vales, JM | 1 |
| Vilalta Castel, E | 1 |
| Lahnborg, G | 1 |
| Crombleholme, W | 1 |
| Landers, D | 1 |
| Ohm-Smith, M | 1 |
| Robbie, MO | 1 |
| Hadley, WK | 1 |
| DeKay, V | 1 |
| Dahrouge, D | 1 |
| Sweet, RL | 1 |
| Sawa, H | 1 |
| Brousil, L | 2 |
| Lomachenko, IN | 1 |
| Tarasov, AA | 1 |
| Andåker, L | 1 |
| Höjer, H | 1 |
| Kihlström, E | 1 |
| Lindhagen, J | 1 |
| Sleptsov, VP | 1 |
| Astakhov, AA | 1 |
| Slezkin, GA | 1 |
| Kharchenko, DM | 1 |
| Leaper, DJ | 1 |
| Kennedy, RH | 1 |
| Sutton, A | 1 |
| Johnson, E | 1 |
| Roberts, N | 1 |
| Leaper, D | 2 |
| Thomas, W | 1 |
| Kennedy, R | 1 |
| Leow, C | 1 |
| Avery, D | 1 |
| Billings, P | 1 |
| Bax, R | 1 |
| Scott, SD | 1 |
| Saddler, B | 1 |
| Lowes, JA | 1 |
| Karran, SJ | 1 |
| Höllwarth, M | 1 |
| Graf, D | 1 |
| Kurz, R | 1 |
| Sauer, H | 1 |
| Hallerbäck, B | 1 |
| Andersson, C | 1 |
| Englund, N | 1 |
| Glise, H | 1 |
| Nihlberg, A | 1 |
| Solhaug, J | 1 |
| Wahlström, B | 1 |
| Go, PM | 1 |
| Luyendijk, R | 1 |
| Munting, JD | 1 |
| Hadary, A | 1 |
| Lernau, OZ | 1 |
| Nissan, S | 1 |
| Thadepalli, H | 1 |
| Moffat, FL | 1 |
| Gilas, T | 1 |
| Calhoun, K | 1 |
| Falk, M | 1 |
| Dalfen, R | 1 |
| Rotstein, LE | 1 |
| Makowka, L | 1 |
| Howard, V | 1 |
| Laing, D | 1 |
| Venturi, D | 1 |
| Törnqvist, A | 1 |
| Forsgren, A | 1 |
| Leandoer, L | 1 |
| Ursing, J | 1 |
| Briedigkeit, H | 1 |
| Clemens, M | 1 |
| Dobrai, I | 1 |
| Szentes, G | 1 |
| Szatmári, S | 1 |
| Farkas, J | 1 |
| Balikian, JP | 1 |
| Uthman, SM | 1 |
| Khouri, NF | 1 |
| Archampong, EQ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase 3, Multicenter, Unblind, Non-Comparative Study To Confirm Efficacy And Safety Of Intravenous Metronidazole In Patients With Intrabdominal Infection In Combination With Intravenous Ceftriaxone[NCT01473836] | Phase 3 | 38 participants (Actual) | Interventional | 2011-11-30 | Completed | ||
| A Randomized, Open Label, Multicentre Phase Iv Study To Evaluate The Efficacy And Safety Of Magnex (Cefoperazone-Sulbactam) In Comparison With Ceftazidime Plus Amikacin And Metronidazole In The Treatment Of Intra-Abdominal Infections[NCT00360607] | Phase 4 | 307 participants (Actual) | Interventional | 2004-07-31 | Completed | ||
| Laparoscopic Lavage for Acute Non-Faeculant Diverticulitis[NCT01019239] | 300 participants (Anticipated) | Interventional | 2010-01-31 | Enrolling by invitation | |||
| Management and Evolution of Acute Diverticulitis With Pericolic Free Gas - a Multicentre Observational Study[NCT04311385] | 1,000 participants (Actual) | Observational | 2020-06-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"The appropriateness of treatment continuation was evaluated on Day 4 by the investigator as continuation, discontinuation or indeterminate based on the clinical response. The percentage of participants was calculated from the following formula; number of participants assessed as continuation over total number of participants that excluding ones assessed as indeterminate multiplied by 100." (NCT01473836)
Timeframe: Baseline to Day 4
| Intervention | percentage of participants (Number) |
|---|---|
| Metronidazole/Ceftriaxone | 100.0 |
"Bacteriological response was evaluated as eradication (eradication, presumed eradication or colonization), persistence, or indeterminate by the data review committee, at Day 4, at the end of treatment (EOT), and the test of cure (TOC: 7 days after EOT). Eradication Rate was calculated from the following formula, number of participants with bacteria eradication, presumed eradication or colonization over total number of participants that excluding ones evaluated as indeterminate multiplied by 100." (NCT01473836)
Timeframe: Baseline to Day 4, EOT (up to 14 days), TOC
| Intervention | percentage of participants (Number) | ||
|---|---|---|---|
| Day 4 | End of Treatment | Test of Cure | |
| Metronidazole/Ceftriaxone | 100.0 | 100.0 | 100.0 |
"Bacteriological response was evaluated as eradication (eradication, presumed eradication or colonization), persistence, or indeterminate by the investigator at the end of treatment (EOT), and the test of cure (TOC: 7 days after EOT). Eradication Rate was calculated from the following formula, number of participants with bacteria eradication, presumed eradication or colonization over total number of participants that excluding ones evaluated as indeterminate multiplied by 100." (NCT01473836)
Timeframe: Baseline to Day 4, EOT (up to 14 days), TOC
| Intervention | percentage of participants (Number) | ||
|---|---|---|---|
| Day 4 | EOT | TOC | |
| Metronidazole/Ceftriaxone | 100.0 | 100.0 | 100.0 |
"Clinical response was evaluated by the data review committee as effective (cured or improved), ineffective (not meeting effective criteria), or indeterminate at the end of treatment (EOT) and the test of cure (TOC: 7 days after EOT) based on clinical symptoms, ultrasound images and necessity of other treatment. TOC was the primary analysis of this outcome measure. Cured = clinical symptoms and abnormal findings at the start of the study were disappeared and considered other antibiotics were not required during the study and after the assessment time point. Improved = clinical symptoms and abnormal findings at the start of the study were improved and considered other antibiotics were not required during the study and after the assessment time point. Response rate was calculated from the following formula; number of participants evaluated as effective over total number of participants that excluding ones evaluated as indeterminate multiplied by 100." (NCT01473836)
Timeframe: Baseline to EOT (up to 14 days), TOC
| Intervention | percentage of participants (Number) | |
|---|---|---|
| End of Treatment (n=30) | Test of Cure (n=30) | |
| Metronidazole/Ceftriaxone | 96.6 | 96.7 |
"Clinical response was evaluated by the investigator as effective (cured or improved), ineffective (not meeting effective criteria), or indeterminate at the end of treatment (EOT) and the test of cure (TOC: 7 days after EOT) based on clinical symptoms, ultrasound images and necessity of other treatment. TOC was the primary analysis of this outcome measure. Cured = clinical symptoms and abnormal findings at the start of the study were disappeared and considered other antibiotics were not required during the study and after the assessment time point. Improved = clinical symptoms and abnormal findings at the start of the study were improved and considered other antibiotics were not required during the study and after the assessment time point. Response rate was calculated from the following formula; number of participants evaluated as effective over total number of participants that excluding ones evaluated as indeterminate multiplied by 100." (NCT01473836)
Timeframe: Baseline to EOT (up to 14 days), TOC
| Intervention | percentage of participants (Number) | |
|---|---|---|
| End of Treatment (n=30) | Test of Cure (n=29) | |
| Metronidazole/Ceftriaxone | 96.7 | 100.0 |
8 reviews available for metronidazole and Peritonitis
| Article | Year |
|---|---|
Sarcina ventriculi : Review of the Literature.
Topics: Anti-Infective Agents; Clostridium Infections; Diagnosis, Differential; Drug Therapy, Combination; E | 2016 |
[Pharmacological rationale for choice of antibiotics for intraabdominal infections].
Topics: Abdominal Abscess; Acetamides; Aminoglycosides; Anti-Bacterial Agents; Anti-Infective Agents; beta-L | 2008 |
Barium peritonitis: a case report and review of literature.
Topics: Aged; Animals; Barium Sulfate; Colon; Colonic Diseases; Dogs; Dysentery, Amebic; Enema; Humans; Male | 1981 |
Carbapenems: monotherapy in intra-abdominal sepsis.
Topics: Adult; Bacterial Infections; Carbapenems; Cefotaxime; Clinical Trials as Topic; Drug Therapy, Combin | 1995 |
[Spontaneous bacterial peritonitis].
Topics: Animals; Ascites; Bacterial Infections; Bacterial Translocation; Cefotaxime; Diagnosis, Differential | 1998 |
[Invasive amebiasis (II): Extra-intestinal forms and complications. Parasitological and serological diagnosis. Treatment].
Topics: Amebiasis; Amebicides; Animals; Anti-Bacterial Agents; Brain Abscess; Digestive System Diseases; Eme | 1985 |
[Antibiotics and drugs active against abdominal infections in newborn infants].
Topics: Abscess; Anti-Bacterial Agents; Bacterial Infections; Humans; Infant, Newborn; Metronidazole; Perito | 1988 |
Animal models for anaerobic infections.
Topics: Animals; Bacteria, Anaerobic; Bacterial Infections; Bacteroides Infections; Disease Models, Animal; | 1985 |
39 trials available for metronidazole and Peritonitis
| Article | Year |
|---|---|
Efficacy and safety of metronidazole injection for the treatment of infectious peritonitis, abdominal abscess and pelvic inflammatory diseases in Japan.
Topics: Abdominal Abscess; Adolescent; Adult; Aged; Anti-Infective Agents; Bacteria; Female; Humans; Japan; | 2015 |
A contrast study of Dermacyn on enterocoely irrigate to control intraoperative infection.
Topics: Abdominal Injuries; Adolescent; Adult; Aged; Anti-Infective Agents, Local; Ascitic Fluid; C-Reactive | 2017 |
Pharmacoeconomics of ciprofloxacin plus metronidazole vs. piperacillin-tazobactam for complicated intra-abdominal infections.
Topics: Abdominal Abscess; Adult; Aged; Anti-Bacterial Agents; Appendicitis; Ciprofloxacin; Cost-Benefit Ana | 2008 |
Cefoperazone-sulbactam for treatment of intra-abdominal infections: results from a randomized, parallel group study in India.
Topics: Abdominal Abscess; Adolescent; Adult; Aged; Amikacin; Anti-Bacterial Agents; Cefoperazone; Ceftazidi | 2008 |
Moxifloxacin for the treatment of patients with complicated intra-abdominal infections (the AIDA Study).
Topics: Abdominal Abscess; Administration, Oral; Adult; Aged; Amoxicillin-Potassium Clavulanate Combination; | 2009 |
Moxifloxacin is non-inferior to combination therapy with ceftriaxone plus metronidazole in patients with community-origin complicated intra-abdominal infections.
Topics: Adult; Anti-Bacterial Agents; Asia; Aza Compounds; Ceftriaxone; Community-Acquired Infections; Doubl | 2009 |
Wound infection after metronidazole infiltration.
Topics: Adult; Anti-Infective Agents; Humans; India; Laparotomy; Metronidazole; Middle Aged; Peritonitis; Su | 2006 |
Molgramostim (GM-CSF) associated with antibiotic treatment in nontraumatic abdominal sepsis: a randomized, double-blind, placebo-controlled clinical trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amikacin; Anti-Bacterial Agents; Antineoplastic Agents; | 2006 |
Short-term antibiotherapy for peritonitis: prospective, randomized trial comparing cefotaxime-metronidazole and clindamycin-tobramycin.
Topics: Cefotaxime; Clindamycin; Clinical Trials as Topic; Diverticulitis; Drug Combinations; Humans; Metron | 1984 |
Metronidazole in the treatment of intra-abdominal sepsis.
Topics: Abdomen; Abscess; Adult; Aged; Appendicitis; Bacterial Infections; Clindamycin; Clinical Trials as T | 1983 |
Antibiotic prophylaxis in acute appendicitis.
Topics: Acute Disease; Administration, Oral; Adolescent; Appendectomy; Appendicitis; Clinical Trials as Topi | 1983 |
Comparison of cefuroxime and gentamicin in combination with metronidazole in the treatment of peritonitis due to perforation of the appendix.
Topics: Adult; Appendicitis; Bacteria; Cefuroxime; Cephalosporins; Clinical Trials as Topic; Drug Therapy, C | 1983 |
Prospective, randomized comparison of metronidazole and clindamycin, each with gentamicin, for the treatment of serious intra-abdominal infection.
Topics: Abdomen; Abscess; Adolescent; Adult; Aged; Anti-Bacterial Agents; Appendicitis; Bacterial Infections | 1983 |
The management of the perforated appendix: a controlled clinical trial.
Topics: Adult; Aged; Appendectomy; Appendicitis; Clinical Trials as Topic; Drug Administration Schedule; Hum | 1982 |
Clinical comparison of antibiotic combinations in the treatment of peritonitis and related mixed aerobic-anaerobic surgical sepsis.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; Cefamandole; Child; Child, Pre | 1980 |
Definition of the role of enterococcus in intraabdominal infection: analysis of a prospective randomized trial.
Topics: Abscess; Adult; Anti-Infective Agents; Bacteremia; Ciprofloxacin; Double-Blind Method; Drug Resistan | 1995 |
The efficacy and safety of isepamicin compared with amikacin in the treatment of intra-abdominal infections.
Topics: Adult; Amikacin; Anti-Bacterial Agents; Cholecystitis; Drug Administration Schedule; Escherichia col | 1995 |
A randomized, double-blind clinical trial comparing cefepime plus metronidazole with imipenem-cilastatin in the treatment of complicated intra-abdominal infections. Cefepime Intra-abdominal Infection Study Group.
Topics: Abdomen; Abdominal Abscess; Adult; Aged; Antitrichomonal Agents; Appendicitis; Cefepime; Cephalospor | 1997 |
[Prospective randomized trial of meropenem versus cefotaxime and metronidazole in the treatment of intraabdominal infections].
Topics: Abdomen; Abdominal Abscess; Adult; Aged; Bacterial Infections; Cefotaxime; Drug Therapy, Combination | 1998 |
Can oral metronidazole substitute parenteral drug therapy in acute appendicitis? A new policy in the management of simple or complicated appendicitis with localized peritonitis: a randomized controlled clinical trial.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Anti-Infective Agents; Appendicitis; Ceftizo | 1999 |
Piperacillin/tazobactam compared with cefuroxime/ metronidazole in the treatment of intra-abdominal infections.
Topics: Abdominal Abscess; Appendicitis; Bacterial Infections; beta-Lactamase Inhibitors; Cefuroxime; Drug T | 1999 |
Metronidazole dental gel as an alternative to scaling and root planing in the treatment of localized adult periodontitis. Is its efficacy proved?
Topics: Adult; Anti-Infective Agents, Local; Dental Scaling; Female; Glycerides; Humans; Male; Metronidazole | 1999 |
[The efficacy of cefepime (Maxipime) in the treatment of abdominal sepsis in surgical patients].
Topics: Abdomen; Aged; Anti-Infective Agents; APACHE; Cefepime; Cephalosporins; Drug Therapy, Combination; F | 1999 |
Piperacillin/Tazobactam versus cefotaxime plus metronidazole for treatment of children with intra-abdominal infections requiring surgery.
Topics: Abdominal Abscess; Adolescent; Appendicitis; Bacterial Infections; Cefotaxime; Child; Child, Prescho | 2001 |
Ceftriaxone vs. ampicillin + metronidazole as prophylaxis against infections after clean-contaminated abdominal surgery.
Topics: Abdomen; Aged; Aged, 80 and over; Ampicillin; Bacterial Infections; Ceftriaxone; Digestive System Su | 1991 |
Piperacillin compared with cefuroxime plus metronidazole in diffuse peritonitis.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Cefuroxime; Drug Therapy, Combination; Fe | 1991 |
[Comparison of 2 antibiotic combinations used for peritonitis. Cefotaxime-clindamycin versus cefotaxime-metronidazole].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cefotaxime; Clindamycin; Drug Therapy, Combination; Fema | 1991 |
Intraincisional antibiotic in addition to systemic antibiotic treatment fails to reduce wound infection rates in contaminated abdominal surgery. A controlled clinical trial.
Topics: Abdomen; Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Cefotaxime; Clinical T | 1989 |
Antibiotic therapy of perforated appendicitis in children: a comparison of amoxycillin/clavulanate with a combination of benzylpenicillin, netilmicin and metronidazole.
Topics: Amoxicillin; Appendicitis; Child; Child, Preschool; Clavulanic Acids; Drug Therapy, Combination; Fem | 1989 |
Sulbactam/ampicillin versus metronidazole/gentamicin in the treatment of severe pelvic infections.
Topics: Ampicillin; beta-Lactamase Inhibitors; Cellulitis; Drug Therapy, Combination; Endometritis; Female; | 1986 |
Stratified duration of prophylactic antimicrobial treatment in emergency abdominal surgery. Metronidazole-fosfomycin vs. metronidazole-gentamicin in 381 patients.
Topics: Abdomen, Acute; Adolescent; Adult; Aged; Appendicitis; Cholecystitis; Clinical Trials as Topic; Drug | 1987 |
Treatment of acute bacterial peritonitis: a trial of imipenem/cilastatin against ampicillin-metronidazole-gentamicin.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ampicillin; Anti-Bacterial Agents; Bacterial Infections; | 1987 |
Treatment of intra-abdominal infections using imipenem/cilastatin.
Topics: Aged; Ampicillin; Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug | 1987 |
Monotherapy for bacterial peritonitis using cefotetan.
Topics: Adult; Bacterial Infections; Cefotetan; Clinical Trials as Topic; Drug Therapy, Combination; Gentami | 1987 |
Comparison of cefotetan versus combination therapy in peritonitis and serious intra-abdominal sepsis.
Topics: Aged; Cefotetan; Cephalosporins; Cephradine; Clinical Trials as Topic; Drug Therapy, Combination; Ge | 1987 |
[Antibiotic treatment of perforated appendicitis in childhood--a prospective study].
Topics: Anti-Bacterial Agents; Appendectomy; Appendicitis; Child; Clinical Trials as Topic; Drug Combination | 1986 |
A prospective randomized study of continuous peritoneal lavage postoperatively in the treatment of purulent peritonitis.
Topics: Adult; Aged; Appendicitis; Bacterial Infections; Cefuroxime; Child; Clinical Trials as Topic; Coloni | 1986 |
[Metronidazole prophylaxis in appendectomy].
Topics: Adolescent; Adult; Aged; Appendectomy; Appendicitis; Child; Double-Blind Method; Female; Humans; Int | 1986 |
Antibiotic treatment during surgery for diffuse peritonitis: a prospective randomized study comparing the effects of cefuroxime and of a cefuroxime and metronidazole combination.
Topics: Adolescent; Adult; Aged; Bacteria; Cefuroxime; Cephalosporins; Combined Modality Therapy; Drug Thera | 1985 |
65 other studies available for metronidazole and Peritonitis
| Article | Year |
|---|---|
Fast determination of free metronidazole in rat plasma and peritoneal fluid using HPLC-UV method.
Topics: Animals; Anti-Infective Agents; Ascitic Fluid; Chromatography, High Pressure Liquid; Metronidazole; | 2023 |
Fitz-Hugh-Curtis Syndrome Presenting as Acute Abdomen.
Topics: Abdomen, Acute; Anti-Bacterial Agents; Cefoxitin; Doxycycline; Exudates and Transudates; Female; Hep | 2020 |
The effects of sponges soaked with chlorhexidine gluconate and metronidazole on safety of colonic anastomosis in an experimental model of peritonitis.
Topics: Anastomosis, Surgical; Animals; Anti-Infective Agents; Chlorhexidine; Colon; Disease Models, Animal; | 2021 |
Improving metronidazole prescription practices in surgical patients: a full cycle audit.
Topics: Abdominal Abscess; Administration, Oral; Aged; Anti-Bacterial Agents; Drug Utilization; Female; Heal | 2021 |
Simplification of first-line antibacterial regimen for complicated appendicitis in children is associated with better adherence to guidelines and reduced use of antibiotics.
Topics: Adolescent; Anti-Bacterial Agents; Appendicitis; Cefotaxime; Child; Drug Therapy, Combination; Femal | 2018 |
Topics: Anti-Bacterial Agents; Ceftriaxone; Humans; Intestinal Perforation; Male; Metronidazole; Middle Aged | 2019 |
The microbiology of bacterial peritonitis due to appendicitis in children.
Topics: Adolescent; Aminoglycosides; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; A | 2014 |
Effects of tissue plasminogen activator in experimentally induced peritonitis.
Topics: Abdominal Abscess; Animals; Anti-Bacterial Agents; Ascitic Fluid; Ceftriaxone; Cytokines; Disease Mo | 2014 |
Plasminogen activator, but not systemic antibiotic therapy, prevents abscess formation in an experimental model of secondary peritonitis.
Topics: Abdominal Abscess; Animals; Anti-Bacterial Agents; Ceftriaxone; Debridement; Fibrinolytic Agents; Ma | 2008 |
Hepatic amebiasis: a reminder of the complications.
Topics: Animals; Antiprotozoal Agents; Diagnosis, Differential; Drainage; Entamoeba histolytica; Genotype; H | 2009 |
Fulminant amoebic colitis during chemotherapy for advanced gastric cancer.
Topics: Animals; Antineoplastic Agents; Antiprotozoal Agents; Dysentery, Amebic; Fatal Outcome; Humans; Inte | 2009 |
Acute abdomen due to vaginal impalement.
Topics: Abdomen, Acute; Adolescent; Anti-Infective Agents; Cefazolin; Coitus; Female; Humans; Laparoscopy; M | 2010 |
Rare case of trichomonal peritonitis.
Topics: Animals; Antiprotozoal Agents; Cattle; Cattle Diseases; Common Variable Immunodeficiency; DNA Finger | 2011 |
[Peritonitis in diverticulitis. How to treat in ambulatory care?].
Topics: Ambulatory Care; Anti-Bacterial Agents; Diverticulitis, Colonic; Drug Therapy, Combination; Humans; | 2011 |
[Bacteriology of community-acquired peritonitis in children treated in the university hospital of Marrakech].
Topics: Adolescent; Anti-Bacterial Agents; Ascitic Fluid; Cephalosporins; Child; Child, Preschool; Community | 2013 |
[Actinomycosis--a rare cause of purulent peritonitis in a woman in fertile age].
Topics: Actinomyces; Actinomycosis; Adult; Anti-Bacterial Agents; Cefuroxime; Cephalosporins; Doxycycline; D | 2001 |
Results of a prospective, randomized, double blind comparison of the efficacy and the safety of sequential ciprofloxacin (intravenous/oral)+metronidazole (intravenous/oral) with ceftriaxone (intravenous)+metronidazole (intravenous/oral) for the treatment
Topics: Abdominal Abscess; Adult; Aged; Bacterial Infections; Ceftriaxone; Ciprofloxacin; Double-Blind Metho | 2003 |
Appendicitis in children: a ten-year update of therapeutic recommendations.
Topics: Abdominal Abscess; Acute Disease; Adolescent; Ampicillin; Antibiotic Prophylaxis; Appendectomy; Appe | 2003 |
[Prospective comparative observational study on the antibiotic treatment of secondary peritonitis in Germany -- efficacy and cost analysis].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Ceftriaxone; Child; Drug Costs; D | 2003 |
[Amebic liver abscess with panperitonitis treated successfully with intravenous injection of metronidazole].
Topics: Antitrichomonal Agents; Humans; Injections, Intravenous; Liver Abscess, Amebic; Male; Metronidazole; | 2004 |
Abnormal enhancing lesion of dentate nuclei causing neurologic symptoms induced by metronidazole toxicity.
Topics: Anti-Infective Agents; Cerebellar Nuclei; Hepatic Encephalopathy; Humans; Magnetic Resonance Imaging | 2005 |
Comparative study of mezlocillin in combination with metronidazole in patients with perforation of the inflamed appendix.
Topics: Anti-Infective Agents; Appendectomy; Appendicitis; Bacteria; Bacterial Infections; Controlled Clinic | 1989 |
Metronidazole improves intestinal microcirculation in septic rats independently of bacterial burden.
Topics: Animals; Anti-Infective Agents; Bacteria, Anaerobic; Cell Adhesion; Cytokines; Endotoxemia; Intestin | 2006 |
Intra-abdominal abscess and peritonitis in an Appaloosa gelding.
Topics: Abdominal Abscess; Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Gentamic | 2006 |
Actinobacillus pleuritis and peritonitis in a quarter horse mare.
Topics: Actinobacillus; Actinobacillus Infections; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, | 2006 |
Actinobacillus peritonitis in a Warmblood gelding.
Topics: Actinobacillus; Actinobacillus Infections; Animals; Anti-Infective Agents; Anti-Inflammatory Agents, | 2006 |
Postpartum hemoperitoneum and septic peritonitis in a Thoroughbred mare.
Topics: Abdominal Cavity; Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Clonixin; | 2006 |
[Primary peritonitis in Sub-Saharian Africa: a 15 case series].
Topics: Adolescent; Adult; Africa South of the Sahara; Amoxicillin-Potassium Clavulanate Combination; Ampici | 2007 |
Towards a rational approach to the treatment of peritonitis: an experimental study in rats.
Topics: Amikacin; Ampicillin; Animals; Cephradine; Disease Models, Animal; Injections, Intramuscular; Isoton | 1984 |
[Metronidazole in the treatment of peritonitis of appendiceal origin].
Topics: Appendicitis; Humans; Metronidazole; Peritonitis | 1984 |
Management of surgical infections.
Topics: Abscess; Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Clindamycin; Drainage; Drug T | 1984 |
Surgical aspects in the management of peritonitis.
Topics: Aged; Aminoglycosides; Bacterial Infections; Cefoxitin; Drainage; Humans; Intraoperative Care; Isoto | 1984 |
[Treatment with metronidazole in patients with destructive appendicitis].
Topics: Adult; Aged; Appendicitis; Female; Humans; Male; Metronidazole; Middle Aged; Peritonitis; Suppuratio | 1983 |
[Antibiotic therapy in severe infections].
Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Cephalosporins; Humans; Infections; Me | 1983 |
Metronidazole in the treatment of surgical infections.
Topics: Clindamycin; Drug Resistance, Microbial; Gentamicins; Humans; Metronidazole; Peritonitis; Premedicat | 1983 |
[Effectiveness of various antimicrobial treatment methods in experimental peritonitis].
Topics: Animals; Bacterial Infections; Cefoxitin; Chloramphenicol; Gentamicins; Metronidazole; Mice; Mice, I | 1983 |
Intravenous metronidazole in the treatment of ruptured amebic liver abscess.
Topics: Adult; Humans; Injections, Intravenous; Liver Abscess, Amebic; Male; Metronidazole; Peritonitis; Rup | 1980 |
Spontaneous Salmonella peritonitis in HIV infection.
Topics: Adult; Anti-Bacterial Agents; Bacteremia; Female; HIV Infections; Humans; Metronidazole; Peritonitis | 1995 |
[Typhoid perforations: experiences in a surgical setting in Cameroon. Apropos of 49 cases].
Topics: Adult; Aged; Ampicillin; Anastomosis, Surgical; Cameroon; Chloramphenicol; Colon; Combined Modality | 1994 |
Laparoscopic management of generalized peritonitis due to perforated colonic diverticula.
Topics: Adult; Aged; Anti-Bacterial Agents; Cephalosporins; Diverticulum, Colon; Female; Follow-Up Studies; | 1996 |
Laparoscopic management of generalized peritonitis due to perforated colonic diverticula.
Topics: Adult; Aged; Anti-Bacterial Agents; Cephalosporins; Diverticulum, Colon; Female; Follow-Up Studies; | 1996 |
Laparoscopic management of generalized peritonitis due to perforated colonic diverticula.
Topics: Adult; Aged; Anti-Bacterial Agents; Cephalosporins; Diverticulum, Colon; Female; Follow-Up Studies; | 1996 |
Laparoscopic management of generalized peritonitis due to perforated colonic diverticula.
Topics: Adult; Aged; Anti-Bacterial Agents; Cephalosporins; Diverticulum, Colon; Female; Follow-Up Studies; | 1996 |
Efficacy of metronidazole lavage in treatment of intraperitoneal sepsis. A prospective study.
Topics: Abdominal Abscess; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bacterial Infe | 1996 |
[Treatment of appendiceal peritonitis].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminoglycosides; Anti-Bacterial Agents; Appendicitis; Ce | 1996 |
[Post-partum malignant amebic colitis. Apropos of a case].
Topics: Adult; Anti-Bacterial Agents; Colectomy; Dysentery, Amebic; Female; Humans; Intestinal Perforation; | 1996 |
Pharmacological protection of NSAID-induced intestinal permeability in the rat: effect of tempo and metronidazole as potential free radical scavengers.
Topics: Administration, Oral; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomar | 1997 |
[Stage-oriented antibiotic therapy of peritonitis. Prospective study].
Topics: Anti-Infective Agents; Bacterial Infections; Cefotaxime; Cephalosporins; Combined Modality Therapy; | 1997 |
[Structural formation of adhesions in abdominal cavity and bowel walls in treatment of peritonitis by sorbent with absorbed metrinidazole or lipoorizinum (experimental study)].
Topics: Abdomen; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Colon; Disease Models, Animal; Drug | 1999 |
Primary peritonitis due to nonenteric salmonellae.
Topics: Adolescent; Aged; Amoxicillin; Cefotaxime; Ciprofloxacin; Clavulanic Acid; Fatal Outcome; Humans; Ma | 1999 |
First documented case of Aeromonas veronii biovar sobria infection in northern Europe.
Topics: Aeromonas; Aged; Anti-Bacterial Agents; Appendiceal Neoplasms; Cefuroxime; Gram-Negative Bacterial I | 2002 |
Invasive amebiasis. I. Amebic dysentery and its complications.
Topics: Adult; Amebiasis; Amebicides; Child, Preschool; Colonic Diseases; Entamoeba histolytica; Granuloma; | 1977 |
Invasive amebiasis. II. Amebic liver abscess and its complications.
Topics: Bronchial Fistula; Cardiac Tamponade; Drainage; Fistula; Heart Diseases; Humans; Liver Abscess, Ameb | 1977 |
Efficacy of tosufloxacin in the treatment of experimentally induced intra-abdominal infections in rats.
Topics: 4-Quinolones; Abscess; Animals; Anti-Infective Agents; Bacterial Infections; Disease Models, Animal; | 1992 |
[Microbial landscape in diffuse suppurative peritonitis with a background of antibacterial therapy].
Topics: Aminoglycosides; Anti-Bacterial Agents; Bacteria; Cephalosporins; Drug Therapy, Combination; Humans; | 1989 |
Evaluation of the use of a protocol in the antimicrobial treatment of intra-abdominal sepsis.
Topics: Adult; Anti-Bacterial Agents; Appendicitis; Bacteria; Drug Administration Schedule; Humans; Metronid | 1985 |
The efficacy of pefloxacin in comparison to gentamicin in the treatment of experimentally induced peritonitis in rats.
Topics: Animals; Anti-Bacterial Agents; Bacteria, Anaerobic; Bacterial Infections; Bacteroides fragilis; Clo | 1986 |
[Long-term experience with rectal administration of metronidazole in the treatment of perforated appendicitis].
Topics: Abdomen; Abscess; Adolescent; Adult; Appendicitis; Child; Female; Humans; Intestinal Perforation; Ma | 1988 |
[Treatment of peritonitis in children using thymalin and metronidazole].
Topics: Adjuvants, Immunologic; Adolescent; Child; Child, Preschool; Combined Modality Therapy; Drug Evaluat | 1988 |
[Metronidazole in the complex treatment of peritonitis of appendicular etiology in children].
Topics: Appendicitis; Bacteroides fragilis; Bacteroides Infections; Child; Combined Modality Therapy; Escher | 1987 |
Abdominal actinomycosis.
Topics: Abscess; Actinomycosis; Appendectomy; Appendicitis; Child; Combined Modality Therapy; Humans; Male; | 1986 |
Further experience with regional radiofrequency hyperthermia and cytotoxic chemotherapy for unresectable hepatic neoplasia.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Body Temperature; Combined Modality Therapy; Fem | 1985 |
Peritoneal lavage with metronidazole.
Topics: Adolescent; Adult; Aged; Cephradine; Child; Child, Preschool; Drug Therapy, Combination; Feces; Fema | 1985 |
[Therapy and prevention with metronidazole].
Topics: Bacteria, Anaerobic; Bacterial Infections; Female; Genital Diseases, Female; Humans; Metronidazole; | 1985 |
[Metronidazole (Klion) in the prevention and therapy of septic complications of appendectomy].
Topics: Acute Disease; Aged; Appendectomy; Humans; Intestinal Perforation; Male; Metronidazole; Middle Aged; | 1985 |
[Rectal administration of metronidazole in the treatment of peritonitis].
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Female; Humans; Male; Metronidazole; Middle Aged; | 1985 |
Intestinal amebiasis. A roentgen analysis of 19 cases including 2 case reports.
Topics: Abscess; Aged; Cecal Diseases; Colitis, Ulcerative; Colonic Diseases; Colonic Neoplasms; Diagnosis, | 1974 |
Peritonitis from amoebic liver abscess.
Topics: Adult; Amebicides; Ampicillin; Humans; Hydrocortisone; Laparotomy; Liver Abscess, Amebic; Male; Metr | 1972 |