metronidazole has been researched along with Penile Diseases in 8 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Penile Diseases: Pathological processes involving the PENIS or its component tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Crohn's disease is a chronic granulomatous inflammatory bowel disorder, often associated with cutaneous manifestations, termed metastatic Crohn's." | 1.36 | Metastatic Crohn's disease: two cases of penile Crohn's and literature review. ( King, D; Lane, VA; Stahlschmidt, J; Subramaniam, R; Sugarman, I; Vajda, P, 2010) |
| "Although infrequent, metastatic Crohn's disease should be suspected in cases of recalcitrant ulcerative conditions, even in the absence of intestinal disease." | 1.33 | Metastatic Crohn's disease mimicking genital pyoderma gangrenosum in an HIV patient. ( Avilés-Izquierdo, JA; Lázaro-Ochaita, P; Longo-Imedio, I; Suárez-Fernández, R, 2005) |
| "Fournier gangrene is a necrotizing fasciitis of the perineal and genital region, which almost exclusively affects men." | 1.33 | [Extensive Fournier gangrene. A dermatologic emergency]. ( Aschoff, R; Baldauf, A; Leike, S; Meurer, M; Wirth, MP, 2006) |
| "We report a case of Crohn's disease affecting penile and scrotal skin." | 1.32 | Metastatic crohn's disease--penile and scrotal involvement. ( Berenguer, J; Del Valle, E; Hernández, C; Jara, J; Martínez-Salamanca, JI; Miralles, P, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vricella, GJ | 1 |
| Coplen, DE | 1 |
| Austin, PF | 1 |
| White, FV | 1 |
| Lane, VA | 1 |
| Vajda, P | 1 |
| King, D | 1 |
| Stahlschmidt, J | 1 |
| Sugarman, I | 1 |
| Subramaniam, R | 1 |
| Martínez-Salamanca, JI | 1 |
| Jara, J | 1 |
| Miralles, P | 1 |
| Berenguer, J | 1 |
| Del Valle, E | 1 |
| Hernández, C | 1 |
| Avilés-Izquierdo, JA | 1 |
| Suárez-Fernández, R | 1 |
| Lázaro-Ochaita, P | 1 |
| Longo-Imedio, I | 1 |
| Aschoff, R | 1 |
| Baldauf, A | 1 |
| Leike, S | 1 |
| Wirth, MP | 1 |
| Meurer, M | 1 |
| Farrell, AM | 1 |
| Black, MM | 1 |
| Bracka, A | 1 |
| Bunker, CB | 1 |
| Mishra, D | 1 |
| Mobashir, M | 1 |
| Zaheer, MS | 1 |
| Sowmini, CN | 1 |
| Vijayalakshmi, K | 1 |
| Chellamuthiah, C | 1 |
| Sundaram, SM | 1 |
2 reviews available for metronidazole and Penile Diseases
| Article | Year |
|---|---|
Granulomatous lymphangitis.
Topics: Biopsy, Needle; Child; Crohn Disease; Follow-Up Studies; Granuloma; Humans; Immunohistochemistry; Ly | 2013 |
Pyoderma gangrenosum of the penis.
Topics: Adult; Anti-Inflammatory Agents; Antitrichomonal Agents; Combined Modality Therapy; Drug Therapy, Co | 1998 |
6 other studies available for metronidazole and Penile Diseases
| Article | Year |
|---|---|
Metastatic Crohn's disease: two cases of penile Crohn's and literature review.
Topics: Anti-Infective Agents; Child; Child, Preschool; Circumcision, Male; Crohn Disease; Diagnosis, Differ | 2010 |
Metastatic crohn's disease--penile and scrotal involvement.
Topics: Adult; Biopsy, Needle; Crohn Disease; Drug Therapy, Combination; Follow-Up Studies; Humans; Immunohi | 2004 |
Metastatic Crohn's disease mimicking genital pyoderma gangrenosum in an HIV patient.
Topics: Adult; Anti-Infective Agents; Anti-Inflammatory Agents; Crohn Disease; Diagnosis, Differential; Gran | 2005 |
[Extensive Fournier gangrene. A dermatologic emergency].
Topics: Adult; Cefotaxime; Combined Modality Therapy; Drug Therapy, Combination; Emergencies; Follow-Up Stud | 2006 |
Fixed drug eruption and cross-reactivity between tinidazole and metronidazole.
Topics: Adult; Cross Reactions; Drug Eruptions; Humans; Male; Metronidazole; Penile Diseases; Tinidazole | 1990 |
Infections of the median raphe of the penis. Report of three cases.
Topics: Adult; Gonorrhea; Humans; Male; Metronidazole; Penicillins; Penile Diseases; Penis; Radiography; Str | 1973 |