metronidazole has been researched along with Pelvic Pain in 3 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Pelvic Pain: Pain in the pelvic region of genital and non-genital origin.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Follow-up is required in women with sexually transmitted infections (STIs) (grade C)." | 2.66 | Pelvic inflammatory diseases: Updated French guidelines. ( Brun, JL; Castan, B; Cazanave, C; Charvériat, A; de Barbeyrac, B; Faure, K; Fritel, X; Graesslin, O; Mignot, S; Verdon, R, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Brun, JL | 1 |
| Castan, B | 1 |
| de Barbeyrac, B | 1 |
| Cazanave, C | 1 |
| Charvériat, A | 1 |
| Faure, K | 1 |
| Mignot, S | 1 |
| Verdon, R | 1 |
| Fritel, X | 1 |
| Graesslin, O | 1 |
| Moraes, ME | 1 |
| Cunha, GH | 1 |
| Bezerra, MM | 1 |
| Fechine, FV | 1 |
| Pontes, AV | 1 |
| Andrade, WS | 1 |
| Frota Bezerra, FA | 1 |
| Moraes, MO | 1 |
| Cavalcanti, PP | 1 |
| Brueseke, TJ | 1 |
| Lane, FL | 1 |
1 review available for metronidazole and Pelvic Pain
| Article | Year |
|---|---|
Pelvic inflammatory diseases: Updated French guidelines.
Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Ceftriaxone; Doxycycline; Female; France; Gen | 2020 |
1 trial available for metronidazole and Pelvic Pain
| Article | Year |
|---|---|
Efficacy of the Mentha crispa in the treatment of women with Trichomonas vaginalis infection.
Topics: Adult; Antitrichomonal Agents; Double-Blind Method; Dyspareunia; Dysuria; Female; Humans; Male; Ment | 2012 |
1 other study available for metronidazole and Pelvic Pain
| Article | Year |
|---|---|
Ischiorectal fossa abscess after pelvic floor injection of botulinum toxin.
Topics: Abscess; Ampicillin; Anti-Bacterial Agents; Anti-Dyskinesia Agents; Anus Diseases; Botulinum Toxins; | 2012 |