Page last updated: 2024-10-31

metronidazole and Parodontosis

metronidazole has been researched along with Parodontosis in 117 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Research Excerpts

ExcerptRelevanceReference
"Poly epsilon-caprolactone (PCL) nanofibers containing metronidazole benzoate (MET) were successfully electrospun and evaluated for periodontal diseases."7.76Controlled release of metronidazole benzoate from poly epsilon-caprolactone electrospun nanofibers for periodontal diseases. ( Jannesari, M; Morshed, M; Varshosaz, J; Zamani, M, 2010)
"The main objective of this study was to develop a local, oral mucoadhesive metronidazole benzoate (MET) delivery system that can be applied and removed by the patient for the treatment of periodontal diseases."7.74Micromatricial metronidazole benzoate film as a local mucoadhesive delivery system for treatment of periodontal diseases. ( Alsarra, IA; Ashri, LY; El-Kamel, AH, 2007)
"The potential use of an adjunctive therapy of metronidazole plus amoxycillin for the subgingival elimination of Actinobacillus actinomycetemcomitans in periodontitis patients was investigated."7.67Metronidazole plus amoxycillin in the treatment of Actinobacillus actinomycetemcomitans associated periodontitis. ( Abbas, F; de Graaff, J; Goené, RJ; Rodenburg, JP; van Winkelhoff, AJ; Winkel, EG, 1989)
"As a healthcare profession, dentists have a role in ensuring the safety of prescribed medicines by reporting adverse drug reactions using the Yellow Card Scheme."6.53Metronidazole and tinnitus: A potential side effect? ( Barker, D; O'Donnell, KL, 2016)
" Review of the drug's pharmacology and potential side effects indicate that it poses little threat to humans of inducing acute toxicity, mutagenesis, or cancer if used according to recommended dosing regimens."6.38The role of metronidazole in the treatment of periodontal diseases. ( Greenstein, G, 1993)
"Several studies have reported adjunctive benefits to scaling and root planing (SRP) of systemic amoxycillin and metronidazole in the treatment of periodontal diseases."5.10Adjunctive effects to non-surgical periodontal therapy of systemic metronidazole and amoxycillin alone and combined. A placebo controlled study. ( Addy, M; Newcombe, RG; Rooney, J; Sprague, SV; Wade, WG, 2002)
"The aim of this study was to examine the effect of periodontal surgery on PGE2 levels in patients treated for advanced adult periodontitis, with and without application of a 25% metronidazole gel over 12 months follow-up."5.09Periodontal flap surgery with 25% metronidazole gel. (2). Effect on gingival crevicular fluid PGE2. ( Collins, AM; Moles, DR; Needleman, IG, 2000)
" This study evaluated chlorhexidine, metronidazole, and tetracycline delivered into periodontal pockets in an acrylic resin vehicle and compared the results with root planed and untreated sites over a three-month follow-up period."5.06Use of antimicrobial containing acrylic strips in the treatment of chronic periodontal disease. A three month follow-up study. ( Addy, M; Hassan, H; Moran, J; Newcombe, R; Wade, W, 1988)
"Poly epsilon-caprolactone (PCL) nanofibers containing metronidazole benzoate (MET) were successfully electrospun and evaluated for periodontal diseases."3.76Controlled release of metronidazole benzoate from poly epsilon-caprolactone electrospun nanofibers for periodontal diseases. ( Jannesari, M; Morshed, M; Varshosaz, J; Zamani, M, 2010)
"The main objective of this study was to develop a local, oral mucoadhesive metronidazole benzoate (MET) delivery system that can be applied and removed by the patient for the treatment of periodontal diseases."3.74Micromatricial metronidazole benzoate film as a local mucoadhesive delivery system for treatment of periodontal diseases. ( Alsarra, IA; Ashri, LY; El-Kamel, AH, 2007)
"Chemical and biological assessment was done in vitro of a form of metronidazole for application into deep pouches in periodontal diseases."3.68[In vitro assessment of metronidazole adapted to the treatment of periodontopathies]. ( Chomyszyn-Gajewska, M; Kasprowicz, A; Kluczykowska, B, 1990)
"The potential use of an adjunctive therapy of metronidazole plus amoxycillin for the subgingival elimination of Actinobacillus actinomycetemcomitans in periodontitis patients was investigated."3.67Metronidazole plus amoxycillin in the treatment of Actinobacillus actinomycetemcomitans associated periodontitis. ( Abbas, F; de Graaff, J; Goené, RJ; Rodenburg, JP; van Winkelhoff, AJ; Winkel, EG, 1989)
" Two double blind studies are reviewed which indicate that metronidazole plus mechanical debridement of the root surfaces is significantly better than placebo plus mechanical debridement in the treatment of advanced cases of periodontitis especially when the periodontal pockets are 6 mm or more in depth."3.67The therapeutic use of antimicrobial agents in patients with periodontal disease. ( Loesche, WJ, 1985)
"As a healthcare profession, dentists have a role in ensuring the safety of prescribed medicines by reporting adverse drug reactions using the Yellow Card Scheme."2.53Metronidazole and tinnitus: A potential side effect? ( Barker, D; O'Donnell, KL, 2016)
"We report a patient with multiple brain abscesses due to infection with A."2.47Brain abscess associated with Aggregatibacter actinomycetemcomitans: case report and review of literature. ( Engström, LJ; Manson, WL; Mooi-Kokenberg, EA; Rahamat-Langendoen, JC; van Vonderen, MG; van Winkelhoff, AJ, 2011)
" Review of the drug's pharmacology and potential side effects indicate that it poses little threat to humans of inducing acute toxicity, mutagenesis, or cancer if used according to recommended dosing regimens."2.38The role of metronidazole in the treatment of periodontal diseases. ( Greenstein, G, 1993)
"Periodontitis is associated with microflorae which may consist of indigenous, exogenous or superinfecting organisms."2.38Antimicrobial therapy in periodontics. ( Slots, J; van Winkelhoff, AJ, 1993)
"Periodontal diseases are common oral diseases that afflict all humans to some degree."2.37Current concepts in periodontal diseases. ( Higgins, TJ; Hunter, N; Knox, KW, 1985)
"Antibiotics play an important role in treating periodontal diseases."1.91Antibiotic Resistance among Fusobacterium, Capnocytophaga, and Leptotrichia Species of the Oral Cavity. ( Attin, T; Bensland, S; Eick, S; Karygianni, L; Kulik, EM; Thurnheer, T, 2023)
"Metronidazole was used as an active agent; its concentration was 12."1.56Electrospun PLA Fibers Containing Metronidazole for Periodontal Disease. ( Budai-Szűcs, M; Burián, K; Csányi, E; Cui, L; Józó, M; Kirschweng, B; Léber, A; Pukánszky, B; Vályi, P, 2020)
"Propylene glycol (PG) was added to increase the solubility of the drug and water was added with PG to control the viscosity."1.42Effect of ethylcellulose and propylene glycol on the controlled-release performance of glyceryl monooleate-mertronidazole periodontal gel. ( Hamudi, FF; Khalil, EA; Sallam, AS, 2015)
"Metronidazole was also highly active against these strains: 316 of 320 Prevotella strains (98."1.35Activity of pradofloxacin against Porphyromonas and Prevotella spp. Implicated in periodontal disease in dogs: susceptibility test data from a European multicenter study. ( Greife, HA; Pridmore, A; Silley, P; Stephan, B, 2008)
"loss of attachment."1.33Studies on periodontitis and analyses of individuals at risk for periodontal diseases. ( Jansson, H, 2006)
"Erythromycin was considerably less active than the other antibiotics against the majority of the periodontal bacteria."1.27Antibiotic susceptibilities of periodontal bacteria. In vitro susceptibilities to eight antimicrobial agents. ( Cohen, S; Gordon, JM; Pappas, JD; Tyler, KZ; Walker, CB, 1985)

Research

Studies (117)

TimeframeStudies, this research(%)All Research%
pre-199034 (29.06)18.7374
1990's35 (29.91)18.2507
2000's28 (23.93)29.6817
2010's16 (13.68)24.3611
2020's4 (3.42)2.80

Authors

AuthorsStudies
Stephan, B1
Greife, HA1
Pridmore, A1
Silley, P1
Thurnheer, T1
Bensland, S1
Eick, S1
Kulik, EM1
Attin, T1
Karygianni, L1
Zupančič, Š1
Casula, L1
Rijavec, T1
Lapanje, A1
Luštrik, M1
Fadda, AM1
Kocbek, P1
Kristl, J1
Budai-Szűcs, M1
Léber, A1
Cui, L1
Józó, M1
Vályi, P1
Burián, K1
Kirschweng, B1
Csányi, E1
Pukánszky, B1
Zago, LHP1
de Annunzio, SR1
de Oliveira, KT1
Barbugli, PA1
Valdes, BR1
Feres, M1
Fontana, CR1
Hasan, F1
Ikram, R1
Abbas, A1
Asadullah, K1
Ye, P1
Chang, J1
Foo, LF1
Yap, BC1
Mombelli, A2
Souto, MLS1
Rovai, ES1
Ganhito, JA1
Holzhausen, M1
Chambrone, L1
Pannuti, CM1
Sallam, AS1
Hamudi, FF1
Khalil, EA1
Gillam, DG1
Turner, W1
Vatne, JF1
Gjermo, P1
Sandvik, L1
Preus, HR1
O'Donnell, KL1
Barker, D1
Bizzarro, S1
Van der Velden, U1
Loos, BG1
Prikuls, VF1
Gerasimenko, MIu1
Moskovets, ON1
Skovorod'ko, SN1
Zamani, M1
Morshed, M1
Varshosaz, J1
Jannesari, M1
Ardila, CM1
López, MA1
Guzmán, IC1
Rahamat-Langendoen, JC1
van Vonderen, MG1
Engström, LJ1
Manson, WL1
van Winkelhoff, AJ5
Mooi-Kokenberg, EA1
Lee, FY1
Chen, DW1
Hu, CC1
Hsieh, YT1
Liu, SJ1
Chan, EC1
Goodson, JM2
Haffajee, AD1
Socransky, SS1
Kent, R1
Teles, R1
Hasturk, H1
Bogren, A1
Van Dyke, T1
Wennstrom, J1
Lindhe, J4
Wang, Y1
Zhang, P1
Jiang, N1
Gong, X1
Meng, L1
Wang, D1
Ou, N1
Zhang, H1
Slots, J2
Müller, HP3
Holderrieth, S1
Burkhardt, U1
Höffler, U1
Niederman, R1
Abdelshehid, G1
Buchmann, R2
Müller, RF2
Van Dyke, TE1
Lange, DE2
Jansson, H3
Bratthall, G2
Söderholm, G2
Ahuja, A1
Rahman, S1
Ali, J1
Chaudhry, R1
Noiri, Y1
Okami, Y1
Narimatsu, M1
Takahashi, Y1
Kawahara, T1
Ebisu, S1
Perioli, L1
Ambrogi, V1
Rubini, D1
Giovagnoli, S1
Ricci, M1
Blasi, P1
Rossi, C1
Al-Mubarak, S1
Al-Nowaiser, A1
Rass, MA1
Alsuwyed, A1
Alghofili, A1
Al-Mubarak, EK1
Ho, A1
Hamberg, K1
Wang, IC1
Roberts, FA1
Ahuja, V1
Shin, RH1
Mudgil, A1
Nanda, V1
Schoor, R1
Schacher, B1
Baron, F1
Ludwig, B1
Valesky, E1
Noack, B1
Eickholz, P1
El-Kamel, AH1
Ashri, LY1
Alsarra, IA1
Liljenberg, B3
Adielson, B2
Börjesson, I2
Clark, DC1
Shenker, S1
Stulginski, P1
Schwartz, S1
Joyston-Bechal, S1
Smales, FC1
Duckworth, R1
Loesche, WJ7
Lekovic, V1
Kenney, EB1
Carranza, FA1
Endres, B1
Mouton, C1
Dextraze, L1
Mayrand, D1
Yi, XQ1
Kowolik, MJ1
MacPhee, IT1
Adams, HD1
Miotti, A1
Sridevi, S1
Babu, RJ1
Mittal, N1
Kumar, DS1
Pandit, JK1
Sander, L2
Frandsen, EV2
Arnbjerg, D2
Warrer, K1
Karring, T1
Theilade, E1
Marsh, BT1
Kilian, M1
Seymour, RA1
Heasman, PA1
Barrett, AP1
Schifter, M1
Peros, WJ1
Ciancio, S1
Greenstein, G1
Giordano, J1
Soehren, S2
Hutchinson, R1
Rau, CF1
Walsh, L1
Schork, MA1
O'Hehir, TE1
Greene, PR1
Giordano, JR2
Ciancio, SG2
Berglundh, T1
Krok, L1
Westfelt, E1
Serino, G1
Al-Arrayed, F1
Thomas, S1
Moran, J2
Urquhart, E1
Addy, M3
Winkel, EG2
Vandenbroucke-Grauls, CM1
Needleman, IG3
Moles, DR2
Collins, AM2
Heinecke, A1
Antczak-Bouckoms, AA1
Weinstein, MC1
Kuriyama, T1
Karasawa, T1
Nakagawa, K1
Yamamoto, E1
Nakamura, S1
Caiafa, AM1
Ghayoumi, N1
Beertsen, W1
Piscaer, M1
Everts, V1
Kinane, DF1
Kaciroti, N1
Rooney, J1
Wade, WG1
Sprague, SV1
Newcombe, RG1
Nachnani, S1
Scuteri, A1
Newman, MG1
Avanessian, AB1
Lomeli, SL1
Teng, YT1
Sodek, J1
McCulloch, CA1
Norling, T1
Lading, P1
Engström, S1
Larsson, K1
Krog, N1
Nissen, SS1
Novaes, AB1
de Uzeda, M1
Fonseca, ME1
Feitosa, AC1
DeRouen, TA1
Mancl, L1
Hujoel, P1
Cattabriga, M1
Di Murro, C1
Paolantonio, M1
Howell, TH1
Huynh, C1
Meyer, J1
Latcham, NL1
Chomyszyn-Gajewska, M1
Kasprowicz, A1
Kluczykowska, B1
Huang, ZR1
Deasy, MJ1
Deasy, PB1
Collins, AE1
MacCarthy, DJ1
Russell, RJ1
Silvestre, B1
Newman, HN1
Masud, M1
Watts, TL1
Rodenburg, JP1
Goené, RJ1
Abbas, F1
de Graaff, J1
Hassan, H1
Wade, W1
Newcombe, R1
Spence, JA1
Aitchison, GU1
Fraser, J1
Mikx, FH1
Llamosas Hernández, E1
Centíes Castella, R1
Hartmann, J2
Flores-de-Jacoby, L2
Walker, CB1
Pappas, JD1
Tyler, KZ1
Cohen, S1
Gordon, JM1
Sterry, KA1
Langeroudi, M1
Dolby, AE1
Higgins, TJ1
Hunter, N1
Knox, KW1
Hanmer, D1
Kimura, K1
Aoki, H1
Fujimaki, I1
Yamaguchi, H1
Obata, J1
Saito, M1
Horibe, K1
Sugár, L1
Sallay, K1
Gürtler, A1
Proctor, DB1
Baker, CG1
Cros, P1
Freidel, M1
Jacquemard, R1
Rousset, JJ1
Lauvergeat, JA1

Clinical Trials (10)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparing the Effect of 0,06 % -, 0,12 % and 0,2 % Chlorhexidine on Plaque, Bleeding and Side Effects in an Experimental Gingivitis Model. A Parallel, Double Masked, Randomized, Placebo-controlled Clinical Trial[NCT02911766]Phase 459 participants (Anticipated)Interventional2016-11-30Not yet recruiting
The Plaque- and Gingivitis Inhibiting Capacity of a Commercially Available Mouthwash Containing Essential Oils and Ethyl Lauroyl Arginate: A Parallel, Split-mouth, Double Blind, Randomized, Placebo-controlled Clinical Study[NCT02884817]Phase 459 participants (Actual)Interventional2015-09-30Completed
The Treatment of Periodontal Diseases. A Randomized, Blinded, Five Years Follow-up, Four-arm, Placebo Controlled Clinical Intervention Trial[NCT01318928]Phase 4184 participants (Actual)Interventional2008-01-31Active, not recruiting
Comparison of Moxifloxacin With Ciprofloxacin/Metronidazole as Adjunctive Therapy to Mechanical Treatment of Patients With Chronic Periodontitis[NCT00805558]Phase 476 participants (Actual)Interventional2009-02-28Completed
Clinical Outcomes Following Non-Surgical Treatment of Chronic Periodontitis, Using Scaling and Root Planing (SRP) in Conjunction With PerioWave, Compared to SRP Alone[NCT00296881]Phase 480 participants (Actual)Interventional2006-04-30Active, not recruiting
A Multicenter, Randomized, Blinded Study of Two Treatments of Photoactivated Disinfection With SRP Against One Treatment of Photoactivated Disinfection With SRP Against SRP Alone in the Treatment of Chronic Periodontitis[NCT00336661]Phase 3105 participants (Actual)Interventional2006-01-31Completed
Photodynamic Disinfection in Combination With Scaling and Root Planing in the Treatment of Chronic Periodontitis[NCT00297531]Phase 4120 participants (Anticipated)Interventional2006-04-30Active, not recruiting
A Multicenter, Randomized, Examiner Blinded Study of Photoactivated Disinfection With Scaling and Root Planing in the Treatment of Chronic Periodontitis[NCT00297518]Phase 440 participants (Actual)Interventional2006-03-31Completed
Observational Study on Cytokine Production by Leukocytes of Papillon-Lefèvre Syndrome Patients and Healthy Probands in Whole Blood Cultures[NCT01116934]17 participants (Actual)Observational2006-07-31Completed
The Use of Single Dose vs Short-Term Peri-Operative Cefazolin in the Prevention of Surgical Site Infection Following Orthognathic Surgery[NCT05852158]Phase 4400 participants (Anticipated)Interventional2024-01-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Serum Concentrations of Interleukin (IL)-1 Beta

Concentrations of IL-8, IL-6, IP-10, interferon (IFN)-gamma, and IL-1 beta, in plasma/RPMI samples were determined by enzyme linked immunosorbent assay (ELISA) according to the manufacturers' instructions (NCT01116934)
Timeframe: 2006

,
Interventionpg/ml (Median)
interleukin-1 betainterleukin-6interferon-inducible protein-10interferon gammainterleukin-8
Healthy Controls896.2145734115633317.444390
Papillon-Lefèvre Syndrome (PLS) Patients1100.006555912902.53704.550520

Reviews

23 reviews available for metronidazole and Parodontosis

ArticleYear
Microbial colonization of the periodontal pocket and its significance for periodontal therapy.
    Periodontology 2000, 2018, Volume: 76, Issue:1

    Topics: Amoxicillin; Anti-Bacterial Agents; Bacteria; Bacterial Physiological Phenomena; Biodiversity; Denta

2018
Efficacy of systemic antibiotics in nonsurgical periodontal therapy for diabetic subjects: a systematic review and meta-analysis.
    International dental journal, 2018, Volume: 68, Issue:4

    Topics: Amoxicillin; Anti-Bacterial Agents; Dental Scaling; Diabetes Mellitus; Doxycycline; Drug Therapy, Co

2018
Metronidazole and tinnitus: A potential side effect?
    British dental journal, 2016, Mar-25, Volume: 220, Issue:6

    Topics: Anti-Infective Agents; Female; Focal Infection, Dental; Gingivitis; Humans; Metronidazole; Middle Ag

2016
Brain abscess associated with Aggregatibacter actinomycetemcomitans: case report and review of literature.
    Journal of clinical periodontology, 2011, Volume: 38, Issue:8

    Topics: Actinobacillus Infections; Adult; Aggregatibacter actinomycetemcomitans; Anti-Bacterial Agents; Anti

2011
Antimicrobial advances in treating periodontal diseases.
    Frontiers of oral biology, 2012, Volume: 15

    Topics: Aggregatibacter actinomycetemcomitans; Amoxicillin; Anti-Bacterial Agents; Dose-Response Relationshi

2012
Selection of antimicrobial agents in periodontal therapy.
    Journal of periodontal research, 2002, Volume: 37, Issue:5

    Topics: Administration, Topical; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents, Local; Ciproflox

2002
Periodontal therapy using local delivery of antimicrobial agents.
    Dental clinics of North America, 2002, Volume: 46, Issue:4

    Topics: Administration, Topical; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Local;

2002
Periodontal therapy using local delivery of antimicrobial agents.
    Dental clinics of North America, 2002, Volume: 46, Issue:4

    Topics: Administration, Topical; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Local;

2002
Periodontal therapy using local delivery of antimicrobial agents.
    Dental clinics of North America, 2002, Volume: 46, Issue:4

    Topics: Administration, Topical; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Local;

2002
Periodontal therapy using local delivery of antimicrobial agents.
    Dental clinics of North America, 2002, Volume: 46, Issue:4

    Topics: Administration, Topical; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Local;

2002
Periodontal therapy using local delivery of antimicrobial agents.
    Dental clinics of North America, 2002, Volume: 46, Issue:4

    Topics: Administration, Topical; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Local;

2002
Periodontal therapy using local delivery of antimicrobial agents.
    Dental clinics of North America, 2002, Volume: 46, Issue:4

    Topics: Administration, Topical; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Local;

2002
Periodontal therapy using local delivery of antimicrobial agents.
    Dental clinics of North America, 2002, Volume: 46, Issue:4

    Topics: Administration, Topical; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Local;

2002
Periodontal therapy using local delivery of antimicrobial agents.
    Dental clinics of North America, 2002, Volume: 46, Issue:4

    Topics: Administration, Topical; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Local;

2002
Periodontal therapy using local delivery of antimicrobial agents.
    Dental clinics of North America, 2002, Volume: 46, Issue:4

    Topics: Administration, Topical; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Local;

2002
Periodontal therapy using local delivery of antimicrobial agents.
    Dental clinics of North America, 2002, Volume: 46, Issue:4

    Topics: Administration, Topical; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Local;

2002
Periodontal therapy using local delivery of antimicrobial agents.
    Dental clinics of North America, 2002, Volume: 46, Issue:4

    Topics: Administration, Topical; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Local;

2002
Periodontal therapy using local delivery of antimicrobial agents.
    Dental clinics of North America, 2002, Volume: 46, Issue:4

    Topics: Administration, Topical; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Local;

2002
Periodontal therapy using local delivery of antimicrobial agents.
    Dental clinics of North America, 2002, Volume: 46, Issue:4

    Topics: Administration, Topical; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Local;

2002
Periodontal therapy using local delivery of antimicrobial agents.
    Dental clinics of North America, 2002, Volume: 46, Issue:4

    Topics: Administration, Topical; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Local;

2002
Periodontal therapy using local delivery of antimicrobial agents.
    Dental clinics of North America, 2002, Volume: 46, Issue:4

    Topics: Administration, Topical; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Local;

2002
Periodontal therapy using local delivery of antimicrobial agents.
    Dental clinics of North America, 2002, Volume: 46, Issue:4

    Topics: Administration, Topical; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Local;

2002
Pharmacological control of periodontal disease. II. Antimicrobial agents.
    Journal of dentistry, 1995, Volume: 23, Issue:1

    Topics: Adult; Anti-Bacterial Agents; Child; Humans; Metronidazole; Periodontal Diseases; Periodontal Pocket

1995
The role of metronidazole in the treatment of periodontal diseases.
    Journal of periodontology, 1993, Volume: 64, Issue:1

    Topics: Animals; Bacteria, Anaerobic; Carcinogenicity Tests; Drug Interactions; Humans; Metronidazole; Molec

1993
Antimicrobial therapy in periodontics.
    Journal of the California Dental Association, 1993, Volume: 21, Issue:11

    Topics: Amoxicillin; Anti-Bacterial Agents; Ciprofloxacin; Clinical Protocols; Dental Prophylaxis; Drug Deli

1993
Locally delivered antimicrobials in periodontal therapy.
    Dental update, 1997, Volume: 24, Issue:5

    Topics: Administration, Topical; Anti-Bacterial Agents; Anti-Infective Agents, Local; Antitrichomonal Agents

1997
Treatment paradigms in periodontal disease.
    Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995), 1997, Volume: 18, Issue:3

    Topics: Anti-Bacterial Agents; Antitrichomonal Agents; Double-Blind Method; Doxycycline; Humans; Metronidazo

1997
Nonsurgical chemical periodontal therapy.
    Periodontology 2000, 1995, Volume: 9

    Topics: Aminoglycosides; Anti-Bacterial Agents; Anti-Infective Agents; Clindamycin; Drug Combinations; Human

1995
Topical antimicrobials: new horizons for management of periodontal disease in general practice?
    Dental update, 1995, Volume: 22, Issue:3

    Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents, Local; General Practice, Dental; Humans; Metron

1995
The use of metronidazole in the treatment of periodontal diseases.
    The Journal of the Western Society of Periodontology/Periodontal abstracts, 2001, Volume: 49, Issue:2

    Topics: Anti-Bacterial Agents; Bacteria, Anaerobic; Gingivitis, Necrotizing Ulcerative; HIV Infections; Huma

2001
Local antimicrobial therapies in periodontal disease.
    Annals of the Royal Australasian College of Dental Surgeons, 2000, Volume: 15

    Topics: Administration, Topical; Anti-Bacterial Agents; Anti-Infective Agents; Biocompatible Materials; Cell

2000
Measurement of associations in periodontal diseases using statistical methods for dependent data.
    Journal of periodontal research, 1991, Volume: 26, Issue:3 Pt 2

    Topics: Aspartate Aminotransferases; Binomial Distribution; Epithelial Attachment; Gingival Crevicular Fluid

1991
General considerations in the treatment of periodontal disease: infection control, medications, and wound healing.
    Current opinion in dentistry, 1991, Volume: 1, Issue:1

    Topics: Alveolar Bone Loss; Dentin Sensitivity; Epithelial Attachment; Humans; Metronidazole; Periodontal Di

1991
Chemotherapeutic agents as adjuncts in the treatment of periodontal disease.
    Current opinion in dentistry, 1991, Volume: 1, Issue:1

    Topics: Anti-Bacterial Agents; Anti-Infective Agents, Local; Antimetabolites; Flurbiprofen; Humans; Metronid

1991
[Periodontal diseases and antibacterial drug treatment].
    Actualites odonto-stomatologiques, 1990, Volume: 44, Issue:170

    Topics: Adult; Alkaloids; Anti-Bacterial Agents; Anti-Infective Agents; Benzophenanthridines; Chlorhexidine;

1990
Chemotherapy. A viable periodontal treatment modality?
    Dental clinics of North America, 1990, Volume: 34, Issue:1

    Topics: Dental Plaque; Humans; Metronidazole; Periodontal Diseases; Tetracycline

1990
[Metronidazole in the treatment of periodontal disease].
    Practica odontologica, 1987, Volume: 8, Issue:3

    Topics: Gingivitis; Humans; Metronidazole; Periodontal Diseases

1987
Current concepts in periodontal diseases.
    The Medical journal of Australia, 1985, May-27, Volume: 142, Issue:11

    Topics: Acute Disease; Adult; Child; Chronic Disease; Dental Plaque; Gingivitis; Gingivitis, Necrotizing Ulc

1985

Trials

27 trials available for metronidazole and Parodontosis

ArticleYear
Effectiveness of local drug delivery system using 1% metronidazole gel and mouthwash in treating periodontal diseases.
    Pakistan journal of pharmaceutical sciences, 2020, Volume: 33, Issue:5

    Topics: Administration, Oral; Anti-Bacterial Agents; Combined Modality Therapy; Dental Scaling; Dinoprostone

2020
Patients' perception of own efforts versus clinically observed outcomes of non-surgical periodontal therapy in a Norwegian population: an observational study.
    BMC oral health, 2015, May-17, Volume: 15

    Topics: Adult; Aged; Anti-Infective Agents; Anti-Infective Agents, Local; Attitude to Health; Chlorhexidine;

2015
Patients' perception of own efforts versus clinically observed outcomes of non-surgical periodontal therapy in a Norwegian population: an observational study.
    BMC oral health, 2015, May-17, Volume: 15

    Topics: Adult; Aged; Anti-Infective Agents; Anti-Infective Agents, Local; Attitude to Health; Chlorhexidine;

2015
Patients' perception of own efforts versus clinically observed outcomes of non-surgical periodontal therapy in a Norwegian population: an observational study.
    BMC oral health, 2015, May-17, Volume: 15

    Topics: Adult; Aged; Anti-Infective Agents; Anti-Infective Agents, Local; Attitude to Health; Chlorhexidine;

2015
Patients' perception of own efforts versus clinically observed outcomes of non-surgical periodontal therapy in a Norwegian population: an observational study.
    BMC oral health, 2015, May-17, Volume: 15

    Topics: Adult; Aged; Anti-Infective Agents; Anti-Infective Agents, Local; Attitude to Health; Chlorhexidine;

2015
Patients' perception of own efforts versus clinically observed outcomes of non-surgical periodontal therapy in a Norwegian population: an observational study.
    BMC oral health, 2015, May-17, Volume: 15

    Topics: Adult; Aged; Anti-Infective Agents; Anti-Infective Agents, Local; Attitude to Health; Chlorhexidine;

2015
Patients' perception of own efforts versus clinically observed outcomes of non-surgical periodontal therapy in a Norwegian population: an observational study.
    BMC oral health, 2015, May-17, Volume: 15

    Topics: Adult; Aged; Anti-Infective Agents; Anti-Infective Agents, Local; Attitude to Health; Chlorhexidine;

2015
Patients' perception of own efforts versus clinically observed outcomes of non-surgical periodontal therapy in a Norwegian population: an observational study.
    BMC oral health, 2015, May-17, Volume: 15

    Topics: Adult; Aged; Anti-Infective Agents; Anti-Infective Agents, Local; Attitude to Health; Chlorhexidine;

2015
Patients' perception of own efforts versus clinically observed outcomes of non-surgical periodontal therapy in a Norwegian population: an observational study.
    BMC oral health, 2015, May-17, Volume: 15

    Topics: Adult; Aged; Anti-Infective Agents; Anti-Infective Agents, Local; Attitude to Health; Chlorhexidine;

2015
Patients' perception of own efforts versus clinically observed outcomes of non-surgical periodontal therapy in a Norwegian population: an observational study.
    BMC oral health, 2015, May-17, Volume: 15

    Topics: Adult; Aged; Anti-Infective Agents; Anti-Infective Agents, Local; Attitude to Health; Chlorhexidine;

2015
Local disinfection with sodium hypochlorite as adjunct to basic periodontal therapy: a randomized controlled trial.
    Journal of clinical periodontology, 2016, Volume: 43, Issue:9

    Topics: Amoxicillin; Anti-Bacterial Agents; Dental Scaling; Disinfection; Follow-Up Studies; Humans; Metroni

2016
Control of periodontal infections: a randomized controlled trial I. The primary outcome attachment gain and pocket depth reduction at treated sites.
    Journal of clinical periodontology, 2012, Volume: 39, Issue:6

    Topics: Amoxicillin; Analysis of Variance; Anti-Infective Agents; Cellulose; Chemotherapy, Adjuvant; Chlorhe

2012
Clinical outcome observed in subjects with recurrent periodontal disease following local treatment with 25% metronidazole gel.
    Journal of periodontology, 2003, Volume: 74, Issue:3

    Topics: Adult; Anti-Infective Agents; Dental Plaque Index; Dental Scaling; Follow-Up Studies; Gels; Gingival

2003
The microbial outcome observed with polymerase chain reaction in subjects with recurrent periodontal disease following local treatment with 25% metronidazole gel.
    Swedish dental journal, 2004, Volume: 28, Issue:2

    Topics: Adult; Aggregatibacter actinomycetemcomitans; Anti-Infective Agents; Colony Count, Microbial; Female

2004
Effectiveness of routine periodontal treatment with and without adjunctive metronidazole therapy in a sample of mentally retarded adolescents.
    Journal of periodontology, 1983, Volume: 54, Issue:11

    Topics: Adolescent; Dental Scaling; Humans; Intellectual Disability; Metronidazole; Periodontal Diseases; Pe

1983
Effect of metronidazole on chronic periodontal disease in subjects using a topically applied chlorhexidine gel.
    Journal of clinical periodontology, 1984, Volume: 11, Issue:1

    Topics: Administration, Topical; Adult; Chlorhexidine; Clinical Trials as Topic; Dental Plaque; Double-Blind

1984
Possibilities for treating periodontal disease as specific anaerobic infections.
    Journal (Canadian Dental Association), 1984, Volume: 50, Issue:6

    Topics: Adult; Animals; Bacteria, Anaerobic; Bacterial Infections; Clinical Trials as Topic; Dental Plaque;

1984
Development and evaluation of acrylic strips of metronidazole for the therapy of periodontal disease.
    Die Pharmazie, 1995, Volume: 50, Issue:2

    Topics: Administration, Topical; Cellulose; Chronic Disease; Dental Plaque; Dibutyl Phthalate; Humans; Methy

1995
Effect of local metronidazole application on periodontal healing following guided tissue regeneration. Clinical findings.
    Journal of periodontology, 1994, Volume: 65, Issue:10

    Topics: Administration, Topical; Adult; Alveolar Bone Loss; Dental Plaque; Female; Gels; Gingival Hemorrhage

1994
Effect of local metronidazole application on periodontal healing following guided tissue regeneration. Microbiological findings.
    Journal of periodontology, 1994, Volume: 65, Issue:10

    Topics: Administration, Topical; Adult; Aggregatibacter actinomycetemcomitans; Alveolar Bone Loss; Colony Co

1994
Nonsurgical treatment of patients with periodontal disease.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 1996, Volume: 81, Issue:5

    Topics: Administration, Oral; Administration, Topical; Adult; Aged; Analysis of Variance; Anti-Bacterial Age

1996
Treatment paradigms in periodontal disease.
    Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995), 1997, Volume: 18, Issue:3

    Topics: Anti-Bacterial Agents; Antitrichomonal Agents; Double-Blind Method; Doxycycline; Humans; Metronidazo

1997
The use of metronidazole and amoxicillin in the treatment of advanced periodontal disease. A prospective, controlled clinical trial.
    Journal of clinical periodontology, 1998, Volume: 25, Issue:5

    Topics: Adult; Aggregatibacter actinomycetemcomitans; Amoxicillin; Anti-Bacterial Agents; Biopsy; Combined M

1998
Periodontal flap surgery with 25% metronidazole gel. (2). Effect on gingival crevicular fluid PGE2.
    Journal of clinical periodontology, 2000, Volume: 27, Issue:3

    Topics: Administration, Topical; Adult; Analysis of Variance; Anti-Infective Agents; Combined Modality Thera

2000
Periodontal flap surgery with 25% metronidazole gel. (1). Clinical outcomes.
    Journal of clinical periodontology, 2000, Volume: 27, Issue:3

    Topics: Administration, Topical; Adult; Aged; Anti-Infective Agents; Combined Modality Therapy; Confidence I

2000
The nonsurgical treatment of patients with periodontal disease: results after five years.
    Journal of the American Dental Association (1939), 2002, Volume: 133, Issue:3

    Topics: Age Factors; Alveolar Bone Loss; Anti-Bacterial Agents; Bacteria, Anaerobic; Bacterial Infections; D

2002
Adjunctive effects to non-surgical periodontal therapy of systemic metronidazole and amoxycillin alone and combined. A placebo controlled study.
    Journal of clinical periodontology, 2002, Volume: 29, Issue:4

    Topics: Adult; Amoxicillin; Analysis of Variance; Anti-Bacterial Agents; Capsules; Chronic Disease; Colony C

2002
[Simplified oral hygiene with subgingival pulsating jet irrigation with and without a dilute metronidazole solution as an adjunct for control of chronic periodontal disease].
    Medecine et hygiene, 1989, May-31, Volume: 47, Issue:1797

    Topics: Adult; Chronic Disease; Humans; Metronidazole; Oral Hygiene; Periodontal Diseases; Periodontal Pocke

1989
The effect of 1% metronidazole gel in routine maintenance of persistent furcation involvement in human beings.
    Journal of periodontology, 1989, Volume: 60, Issue:12

    Topics: Adult; Aged; Bacteria; Combined Modality Therapy; Confidence Intervals; Delayed-Action Preparations;

1989
Use of antimicrobial containing acrylic strips in the treatment of chronic periodontal disease. A three month follow-up study.
    Journal of periodontology, 1988, Volume: 59, Issue:9

    Topics: Adult; Aged; Chlorhexidine; Chronic Disease; Dental Scaling; Drug Implants; Female; Follow-Up Studie

1988
[Systemic metronidazole therapy and/or subgingival scaling with root planing. I. Clinical results].
    Deutsche zahnarztliche Zeitschrift, 1986, Volume: 41, Issue:6

    Topics: Adult; Dental Prophylaxis; Dental Scaling; Female; Humans; Male; Metronidazole; Middle Aged; Periodo

1986
[Systemic metronidazole therapy and/or subgingival scaling and root planing. II. Development of clinical parameters in relation to the changes in the composition of the associated subgingival microflora].
    Deutsche zahnarztliche Zeitschrift, 1986, Volume: 41, Issue:6

    Topics: Bacteria; Dental Prophylaxis; Dental Scaling; Humans; Metronidazole; Periodontal Diseases; Spirochae

1986
Metronidazole as an adjunct to periodontal therapy with sub-gingival curettage.
    British dental journal, 1985, Mar-09, Volume: 158, Issue:5

    Topics: Adult; Bacteria; Clinical Trials as Topic; Double-Blind Method; Female; Gingival Crevicular Fluid; H

1985
[A clinical observation on the effect of metronidazole for periodontal disease with fetor ex ore by double blind test].
    Shika gakuho. Dental science reports, 1973, Volume: 73, Issue:2

    Topics: Halitosis; Metronidazole; Periodontal Diseases

1973
[Deodorant effects of flyagyl by double-blind method (on the periodontal disease) (author's transl)].
    Nihon Shishubyo Gakkai kaishi, 1973, Volume: 15, Issue:2

    Topics: Adult; Aged; Deodorants; Humans; Metronidazole; Middle Aged; Periodontal Diseases

1973

Other Studies

68 other studies available for metronidazole and Parodontosis

ArticleYear
Activity of pradofloxacin against Porphyromonas and Prevotella spp. Implicated in periodontal disease in dogs: susceptibility test data from a European multicenter study.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Bacteroidaceae Infections; Dog Diseases; Dogs; Europe; Fluoroquinolo

2008
Antibiotic Resistance among Fusobacterium, Capnocytophaga, and Leptotrichia Species of the Oral Cavity.
    Oral health & preventive dentistry, 2023, Mar-15, Volume: 21, Issue:1

    Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Anti-Infective Ag

2023
Sustained release of antimicrobials from double-layer nanofiber mats for local treatment of periodontal disease, evaluated using a new micro flow-through apparatus.
    Journal of controlled release : official journal of the Controlled Release Society, 2019, 12-28, Volume: 316

    Topics: Anti-Bacterial Agents; Chitosan; Ciprofloxacin; Delayed-Action Preparations; Drug Carriers; Drug Del

2019
Electrospun PLA Fibers Containing Metronidazole for Periodontal Disease.
    Drug design, development and therapy, 2020, Volume: 14

    Topics: Aggregatibacter actinomycetemcomitans; Anti-Bacterial Agents; Drug Liberation; Eikenella corrodens;

2020
Antimicrobial photodynamic therapy against metronidazole-resistant dental plaque bactéria.
    Journal of photochemistry and photobiology. B, Biology, 2020, Volume: 209

    Topics: Anti-Bacterial Agents; Biofilms; Chlorophyllides; Curcumin; Dental Plaque; Drug Resistance, Bacteria

2020
An early report: a modified porphyrin-linked metronidazole targeting intracellular Porphyromonas gingivalis in cultured oral epithelial cells.
    International journal of oral science, 2017, Volume: 9, Issue:3

    Topics: Cells, Cultured; Epithelial Cells; Flow Cytometry; Humans; Metronidazole; Microscopy, Confocal; Mout

2017
Effect of ethylcellulose and propylene glycol on the controlled-release performance of glyceryl monooleate-mertronidazole periodontal gel.
    Pharmaceutical development and technology, 2015, Volume: 20, Issue:2

    Topics: Adhesiveness; Animals; Anti-Infective Agents; Cellulose; Chickens; Delayed-Action Preparations; Drug

2015
Antibiotics in the treatment of periodontal disease: a guide for the general dental practitioner.
    Primary dental journal, 2014, Volume: 3, Issue:3

    Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Bacterial Agents; Biofilms; Chronic Periodontitis

2014
[Gel Metrogil Denta photopheresis use in comprehensive treatment of patients with chronic generalized parodontitis].
    Stomatologiia, 2008, Volume: 87, Issue:4

    Topics: Adult; Chlorhexidine; Chronic Disease; Combined Modality Therapy; Dental Care; Drug Combinations; Ge

2008
Controlled release of metronidazole benzoate from poly epsilon-caprolactone electrospun nanofibers for periodontal diseases.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2010, Volume: 75, Issue:2

    Topics: Anti-Infective Agents; Crystallization; Delayed-Action Preparations; Dimethylformamide; Electric Con

2010
High resistance against clindamycin, metronidazole and amoxicillin in Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans isolates of periodontal disease.
    Medicina oral, patologia oral y cirugia bucal, 2010, Nov-01, Volume: 15, Issue:6

    Topics: Aggregatibacter actinomycetemcomitans; Amoxicillin; Anti-Infective Agents; Clindamycin; Drug Resista

2010
In vitro and in vivo investigation of drug-eluting implants for the treatment of periodontal disease.
    AAPS PharmSciTech, 2011, Volume: 12, Issue:4

    Topics: Absorbable Implants; Animals; Anti-Infective Agents; Chemistry, Pharmaceutical; Chromatography, High

2011
Simultaneous quantification of metronidazole, tinidazole, ornidazole and morinidazole in human saliva.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2012, Jun-15, Volume: 899

    Topics: Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Female; Humans; Male; Metronidazole; Ni

2012
UM study: antibiotics may help some periodontal patients.
    The Journal of the Michigan Dental Association, 2002, Volume: 84, Issue:7

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Dental Scaling; Doxycycline; Humans; Metronidazole; Pe

2002
In vitro antimicrobial susceptibility of oral strains of Actinobacillus actinomycetemcomitans to seven antibiotics.
    Journal of clinical periodontology, 2002, Volume: 29, Issue:8

    Topics: Aggregatibacter actinomycetemcomitans; Anti-Bacterial Agents; Anti-Infective Agents; Cluster Analysi

2002
Change of antibiotic susceptibility following periodontal therapy. A pilot study in aggressive periodontal disease.
    Journal of clinical periodontology, 2003, Volume: 30, Issue:3

    Topics: Adult; Aggregatibacter actinomycetemcomitans; Amoxicillin-Potassium Clavulanate Combination; Anti-Ba

2003
Effect of dental films containing amoxycillin and metronidazole on periodontal pathogens: microbiological response.
    Die Pharmazie, 2003, Volume: 58, Issue:10

    Topics: Absorbable Implants; Amoxicillin; Anti-Infective Agents; Bacteria; Bacteria, Anaerobic; Cariostatic

2003
Effects of chlorhexidine, minocycline, and metronidazole on Porphyromonas gingivalis strain 381 in biofilms.
    Journal of periodontology, 2003, Volume: 74, Issue:11

    Topics: Adenosine Triphosphate; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Local;

2003
Novel mucoadhesive buccal formulation containing metronidazole for the treatment of periodontal disease.
    Journal of controlled release : official journal of the Controlled Release Society, 2004, Mar-24, Volume: 95, Issue:3

    Topics: Acrylic Resins; Adhesives; Animals; Cellulose; Chemistry, Pharmaceutical; Drug Delivery Systems; Dru

2004
Antibiotic prescription and dental practice within Saudi Arabia; the need to reinforce guidelines and implement specialty needs.
    Journal of the International Academy of Periodontology, 2004, Volume: 6, Issue:2

    Topics: Anti-Bacterial Agents; Drug Costs; Drug Prescriptions; Drug Utilization; Follow-Up Studies; General

2004
Adjunctive periodontal therapies.
    Practical procedures & aesthetic dentistry : PPAD, 2005, Volume: 17, Issue:4

    Topics: Anti-Bacterial Agents; Biofilms; Chlorhexidine; Humans; Metronidazole; Penicillins; Periodontal Dise

2005
Papillon-Lefèvre syndrome: a successful outcome.
    Journal of periodontology, 2005, Volume: 76, Issue:11

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Child; Combined Modality Therapy; Dental

2005
Studies on periodontitis and analyses of individuals at risk for periodontal diseases.
    Swedish dental journal. Supplement, 2006, Issue:180

    Topics: Adult; Anti-Infective Agents; Chronic Disease; Diabetes Mellitus, Type 2; Female; Genetic Predisposi

2006
Periodontal therapy in siblings with Papillon-Lefèvre syndrome and tinea capitis: a report of two cases.
    Journal of clinical periodontology, 2006, Volume: 33, Issue:11

    Topics: Aggregatibacter actinomycetemcomitans; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Ch

2006
Micromatricial metronidazole benzoate film as a local mucoadhesive delivery system for treatment of periodontal diseases.
    AAPS PharmSciTech, 2007, Sep-14, Volume: 8, Issue:3

    Topics: Adhesiveness; Anti-Infective Agents; Chitosan; Delayed-Action Preparations; Humans; Metronidazole; M

2007
The effect of metronidazole therapy on human periodontal disease.
    Journal of periodontal research, 1982, Volume: 17, Issue:5

    Topics: Bacteria; Dental Scaling; Humans; Metronidazole; Periodontal Diseases; Subgingival Curettage; Time F

1982
Use of metronidazole as a probe in the study of human periodontal disease.
    Journal of clinical periodontology, 1983, Volume: 10, Issue:1

    Topics: Adult; Bacteria; Female; Humans; Male; Metronidazole; Middle Aged; Oral Hygiene; Periodontal Disease

1983
The effect of metronidazole on human periodontal disease. A clinical and bacteriological study.
    Journal of periodontology, 1983, Volume: 54, Issue:8

    Topics: Adult; Bacteria; Female; Humans; Metronidazole; Middle Aged; Periodontal Diseases; Periodontal Index

1983
[Susceptibility of potential periodontopathic bacteria to metronidazole, spiramycin and their combination].
    Journal de biologie buccale, 1984, Volume: 12, Issue:1

    Topics: Bacteria; Bacteroides; Dental Plaque; Drug Combinations; Erythromycin; Humans; Leucomycins; Metronid

1984
[Preliminary survey on treatment of periodontal diseases with metronidazol].
    Zhonghua kou qiang ke za zhi [Chinese journal of stomatology], 1983, Volume: 18, Issue:4

    Topics: Adolescent; Adult; Child; Female; Follow-Up Studies; Humans; Male; Metronidazole; Middle Aged; Perio

1983
Is periodontal disease preventable?
    Journal of the Royal Society of Medicine, 1983, Volume: 76, Issue:10

    Topics: Humans; Metronidazole; Periodontal Diseases

1983
[Metronidazole in dentistry].
    Rivista italiana di stomatologia, 1982, Volume: 51, Issue:4

    Topics: Gingivitis; Humans; Metronidazole; Mouth Diseases; Periodontal Diseases

1982
Antibiotic gels for periodontal disease.
    Drug and therapeutics bulletin, 1994, Jun-16, Volume: 32, Issue:6

    Topics: Gels; Humans; Metronidazole; Minocycline; Oral Hygiene; Periodontal Diseases

1994
Topical antibiotics and gastric flora.
    British dental journal, 1995, Feb-11, Volume: 178, Issue:3

    Topics: Administration, Topical; Drug Resistance, Microbial; Helicobacter pylori; Humans; Metronidazole; Per

1995
Topical antibiotics and gastric flora.
    British dental journal, 1995, Feb-11, Volume: 178, Issue:3

    Topics: Administration, Topical; Drug Resistance, Microbial; Drug Resistance, Multiple; Helicobacter pylori;

1995
Antibiotic strategy in orofacial/head and neck infections in severe neutropenia.
    Oral surgery, oral medicine, and oral pathology, 1994, Volume: 77, Issue:4

    Topics: Adolescent; Adult; Aged; Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Clinical Prot

1994
Re: Treatment of periodontal diseases with metronidazole (J Periodontol 1993;64:1-15)
    Journal of periodontology, 1993, Volume: 64, Issue:9

    Topics: Bacteria, Anaerobic; Bacterial Infections; Benzoylarginine-2-Naphthylamide; Drug Resistance, Microbi

1993
Use and abuse of antibiotics in periodontal therapy.
    Dental economics - oral hygiene, 1993, Volume: 83, Issue:6

    Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Clavulanic Acids;

1993
Here's the 'scoop' on why everyone is suddenly asking about antibiotics.
    RDH, 1996, Volume: 16, Issue:9

    Topics: Anti-Bacterial Agents; Antitrichomonal Agents; Dental Scaling; Humans; Mass Media; Metronidazole; Ne

1996
Effect of addition of antimicrobial drugs to human collagen membrane.
    Clinical materials, 1993, Volume: 12, Issue:3

    Topics: Aggregatibacter actinomycetemcomitans; Collagen; Collagenases; Dose-Response Relationship, Immunolog

1993
On the dosage of antibiotics in clinical trials.
    Journal of clinical periodontology, 1999, Volume: 26, Issue:11

    Topics: Anti-Infective Agents; Combined Modality Therapy; Humans; Metronidazole; Periodontal Diseases; Perio

1999
Actinobacillus actinomycetemcomitans in destructive periodontal disease. Three-year follow-up results.
    Journal of periodontology, 2000, Volume: 71, Issue:3

    Topics: Actinobacillus Infections; Adult; Aggregatibacter actinomycetemcomitans; Amoxicillin; Anti-Bacterial

2000
Cost-effectiveness analysis of periodontal disease control.
    Journal of dental research, 1987, Volume: 66, Issue:11

    Topics: Alveoloplasty; Anti-Bacterial Agents; Anti-Infective Agents; Cost-Benefit Analysis; Decision Support

1987
Incidence of beta-lactamase production and antimicrobial susceptibility of anaerobic gram-negative rods isolated from pus specimens of orofacial odontogenic infections.
    Oral microbiology and immunology, 2001, Volume: 16, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ampicillin Resistance; Anti-Bacterial Agents; Bacteroida

2001
In vitro antimicrobial susceptibilities of three Porphyromonas spp and responses in the oral cavity of cats to treatment with selected antimicrobial drugs.
    Australian veterinary journal, 2000, Volume: 78, Issue:12

    Topics: Animals; Anti-Bacterial Agents; Bacteroidaceae Infections; Cat Diseases; Cats; Clindamycin; Doxycycl

2000
Generalized cervical root resorption associated with periodontal disease.
    Journal of clinical periodontology, 2001, Volume: 28, Issue:11

    Topics: Acids; Adult; Aggregatibacter actinomycetemcomitans; Alveolar Bone Loss; Amoxicillin; Anti-Bacterial

2001
The specific plaque hypothesis and the antimicrobial treatment of periodontal disease.
    Dental update, 1992, Volume: 19, Issue:2

    Topics: Bacteria, Anaerobic; Bacteroides; Benzoylarginine-2-Naphthylamide; Dental Plaque; Humans; Metronidaz

1992
E-test: a new technique for antimicrobial susceptibility testing for periodontal microorganisms.
    Journal of periodontology, 1992, Volume: 63, Issue:7

    Topics: Adult; Aged; Aggregatibacter actinomycetemcomitans; Ampicillin; Anti-Bacterial Agents; Bacteria; Bac

1992
Gingival crevicular fluid gelatinase and its relationship to periodontal disease in human subjects.
    Journal of periodontal research, 1992, Volume: 27, Issue:5

    Topics: Adult; Aged; Analysis of Variance; Biomarkers; Chi-Square Distribution; Clinical Enzyme Tests; Colla

1992
Formulation of a drug delivery system based on a mixture of monoglycerides and triglycerides for use in the treatment of periodontal disease.
    Journal of clinical periodontology, 1992, Volume: 19, Issue:9 Pt 2

    Topics: Biodegradation, Environmental; Chemistry, Pharmaceutical; Crystallization; Delayed-Action Preparatio

1992
The effect of subinhibitory concentrations of metronidazole and tetracycline on the ultrastructure of periodontopathic bacteria.
    The Journal of antimicrobial chemotherapy, 1991, Volume: 28, Issue:1

    Topics: Actinobacillus; Bacteroides; Humans; Metronidazole; Microbial Sensitivity Tests; Periodontal Disease

1991
Role of anaerobic bacteria in periodontal disease.
    The Annals of otology, rhinology & laryngology. Supplement, 1991, Volume: 154

    Topics: Bacteria, Anaerobic; Bacterial Infections; Clinical Trials as Topic; Humans; Metronidazole; Periodon

1991
Use of the acid-etch technique to maintain antimicrobial-containing acrylic resin strips in situ.
    Quintessence international (Berlin, Germany : 1985), 1990, Volume: 21, Issue:8

    Topics: Acid Etching, Dental; Acrylic Resins; Composite Resins; Delayed-Action Preparations; Humans; Metroni

1990
[In vitro assessment of metronidazole adapted to the treatment of periodontopathies].
    Czasopismo stomatologiczne, 1990, Volume: 43, Issue:5

    Topics: Evaluation Studies as Topic; Humans; Metronidazole; Periodontal Diseases; Periodontal Pocket

1990
[The absorbent metronidazole gelatin sponge used in treating periodontal disease].
    Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology, 1990, Volume: 25, Issue:1

    Topics: Adolescent; Adult; Aged; Bacteria, Anaerobic; Female; Gelatin Sponge, Absorbable; Humans; Male; Metr

1990
Use of strips containing tetracycline hydrochloride or metronidazole for the treatment of advanced periodontal disease.
    The Journal of pharmacy and pharmacology, 1989, Volume: 41, Issue:10

    Topics: Administration, Topical; Calorimetry, Differential Scanning; Dental Plaque; Gingiva; Humans; Metroni

1989
[Subgingival administration of antimicrobials in periodontology. Update].
    L' Information dentaire, 1989, May-11, Volume: 71, Issue:19

    Topics: Chlorhexidine; Dental Plaque; Humans; Metronidazole; Periodontal Diseases; Tetracyclines; Therapeuti

1989
Metronidazole plus amoxycillin in the treatment of Actinobacillus actinomycetemcomitans associated periodontitis.
    Journal of clinical periodontology, 1989, Volume: 16, Issue:2

    Topics: Actinobacillus; Adolescent; Adult; Aggressive Periodontitis; Amoxicillin; Bacteroides; Drug Combinat

1989
Development of periodontal disease in a single flock of sheep: clinical signs, morphology of subgingival plaque and influence of antimicrobial agents.
    Research in veterinary science, 1988, Volume: 45, Issue:3

    Topics: Animals; Body Weight; Dental Plaque; Female; Gingiva; Metronidazole; Oxytetracycline; Periodontal Di

1988
[Antibacterial agents in periodontal therapy].
    Nederlands tijdschrift voor tandheelkunde, 1988, Volume: 95, Issue:7

    Topics: Anti-Infective Agents; Combined Modality Therapy; Humans; Metronidazole; Periodontal Diseases; Tetra

1988
Antibacterial agents and periodontal therapy.
    The New York state dental journal, 1986, Volume: 52, Issue:5

    Topics: Administration, Topical; Anti-Bacterial Agents; Bacteria; Bacterial Physiological Phenomena; Clindam

1986
The therapeutic use of antimicrobial agents in patients with periodontal disease.
    Scandinavian journal of infectious diseases. Supplementum, 1985, Volume: 46

    Topics: Bacteria, Anaerobic; Bacterial Infections; Bacteroides Infections; Combined Modality Therapy; Debrid

1985
Antibiotic susceptibilities of periodontal bacteria. In vitro susceptibilities to eight antimicrobial agents.
    Journal of periodontology, 1985, Volume: 56, Issue:11 Suppl

    Topics: Actinobacillus; Anti-Bacterial Agents; Bacteria; Clindamycin; Erythromycin; Humans; Metronidazole; P

1985
Antibiotics for periodontal disease. When, why and what.
    Journal (Canadian Dental Association), 1985, Volume: 51, Issue:10

    Topics: Adult; Anti-Bacterial Agents; Humans; Leucomycins; Metronidazole; Penicillins; Periodontal Diseases;

1985
[The effect of metranidazol (Klion) therapy on paradontopathies].
    Fogorvosi szemle, 1971, Volume: 64, Issue:5

    Topics: Humans; Metronidazole; Periodontal Diseases

1971
Treatment of acute necrotizing ulcerative gingivitis with metronidazole.
    Journal of the Canadian Dental Association, 1971, Volume: 37, Issue:10

    Topics: Adolescent; Adult; Dental Prophylaxis; Gingivitis, Necrotizing Ulcerative; Humans; Metronidazole; Pe

1971
[Value of the synergic association metronidazole-spiramycin in current dental practice. Report of 63 cases].
    Revue francaise d'odonto-stomatologie, 1971, Volume: 18, Issue:8

    Topics: Adolescent; Adult; Aged; Child; Dental Pulp Diseases; Drug Synergism; Female; Humans; Leucomycins; M

1971
[Oral protozoa. Epidemiologic inquiry].
    La Presse medicale, 1971, Jul-03, Volume: 79, Issue:33

    Topics: Adult; Entamoeba; Humans; Male; Metronidazole; Mouth; Periodontal Diseases; Protozoan Infections; Ru

1971