metronidazole has been researched along with Parasitic Diseases, Animal in 2 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Parasitic Diseases, Animal: Animal diseases caused by PARASITES.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pan, Y | 1 |
| Yi, J | 1 |
| Zhou, B | 1 |
| Xie, S | 1 |
| Chen, D | 1 |
| Tao, Y | 1 |
| Qu, W | 1 |
| Liu, Z | 1 |
| Huang, L | 1 |
| Yuan, Z | 1 |
| Nickol, DR | 1 |
| Tufts, DM | 1 |
1 trial available for metronidazole and Parasitic Diseases, Animal
| Article | Year |
|---|---|
Single-dose metronidazole clears Opalina sp. from juvenile Bufo woodhousii.
Topics: Administration, Oral; Animals; Antiprotozoal Agents; Bufonidae; Metronidazole; Parasitic Diseases, A | 2013 |
1 other study available for metronidazole and Parasitic Diseases, Animal
| Article | Year |
|---|---|
Disposition and Residue Depletion of Metronidazole in Pigs and Broilers.
Topics: Animals; Antiprotozoal Agents; Drug Monitoring; Metronidazole; Parasitic Diseases, Animal; Pharmacok | 2017 |