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metronidazole and Parasitemia

metronidazole has been researched along with Parasitemia in 2 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Parasitemia: The presence of parasites (especially malarial parasites) in the blood. (Dorland, 27th ed)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cross, RM1
Flanigan, DL1
Monastyrskyi, A1
LaCrue, AN1
Sáenz, FE1
Maignan, JR1
Mutka, TS1
White, KL1
Shackleford, DM1
Bathurst, I1
Fronczek, FR1
Wojtas, L1
Guida, WC1
Charman, SA1
Burrows, JN1
Kyle, DE1
Manetsch, R1
Giannini, G1
Battistuzzi, G1

Other Studies

2 other studies available for metronidazole and Parasitemia

ArticleYear
Orally bioavailable 6-chloro-7-methoxy-4(1H)-quinolones efficacious against multiple stages of Plasmodium.
    Journal of medicinal chemistry, 2014, Nov-13, Volume: 57, Issue:21

    Topics: Animals; Antimalarials; Humans; Inhibitory Concentration 50; Malaria; Mice; Microsomes, Liver; Paras

2014
Exploring in vitro and in vivo Hsp90 inhibitors activity against human protozoan parasites.
    Bioorganic & medicinal chemistry letters, 2015, Feb-01, Volume: 25, Issue:3

    Topics: Animals; Antiprotozoal Agents; Cell Line, Tumor; Disease Models, Animal; HSP90 Heat-Shock Proteins;

2015