metronidazole has been researched along with Papilloma in 3 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Papilloma: A circumscribed benign epithelial tumor projecting from the surrounding surface; more precisely, a benign epithelial neoplasm consisting of villous or arborescent outgrowths of fibrovascular stroma covered by neoplastic cells. (Stedman, 25th ed)
Excerpt | Relevance | Reference |
---|---|---|
"The results of combined treatment of 98 laryngeal cancer patients followed up for 1." | 1.27 | [Combined (radiation and surgical) treatment of laryngeal cancer patients using metronidazole]. ( Andreev, VG, 1985) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Schneider, GT | 1 |
Andreev, VG | 1 |
Rodgerson, EB | 1 |
3 other studies available for metronidazole and Papilloma
Article | Year |
---|---|
Vaginal infections. How to identify and treat them.
Topics: Adolescent; Adult; Candidiasis; Child; Chlamydia Infections; Female; Haemophilus Infections; Herpes | 1983 |
[Combined (radiation and surgical) treatment of laryngeal cancer patients using metronidazole].
Topics: Adult; Aged; Carcinoma, Squamous Cell; Combined Modality Therapy; Humans; Laryngeal Neoplasms; Laryn | 1985 |
Vulvovaginal papillomas and trichomonas vaginalis.
Topics: Female; Humans; Metronidazole; Papilloma; Podophyllin; Trichomonas Vaginitis; Vaginal Neoplasms; Vul | 1972 |