Page last updated: 2024-10-31

metronidazole and Papilloma

metronidazole has been researched along with Papilloma in 3 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Papilloma: A circumscribed benign epithelial tumor projecting from the surrounding surface; more precisely, a benign epithelial neoplasm consisting of villous or arborescent outgrowths of fibrovascular stroma covered by neoplastic cells. (Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
"The results of combined treatment of 98 laryngeal cancer patients followed up for 1."1.27[Combined (radiation and surgical) treatment of laryngeal cancer patients using metronidazole]. ( Andreev, VG, 1985)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schneider, GT1
Andreev, VG1
Rodgerson, EB1

Other Studies

3 other studies available for metronidazole and Papilloma

ArticleYear
Vaginal infections. How to identify and treat them.
    Postgraduate medicine, 1983, Volume: 73, Issue:2

    Topics: Adolescent; Adult; Candidiasis; Child; Chlamydia Infections; Female; Haemophilus Infections; Herpes

1983
[Combined (radiation and surgical) treatment of laryngeal cancer patients using metronidazole].
    Meditsinskaia radiologiia, 1985, Volume: 30, Issue:8

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Combined Modality Therapy; Humans; Laryngeal Neoplasms; Laryn

1985
Vulvovaginal papillomas and trichomonas vaginalis.
    Obstetrics and gynecology, 1972, Volume: 40, Issue:3

    Topics: Female; Humans; Metronidazole; Papilloma; Podophyllin; Trichomonas Vaginitis; Vaginal Neoplasms; Vul

1972