metronidazole has been researched along with Overweight in 1 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Overweight: A status with BODY WEIGHT that is above certain standards. In the scale of BODY MASS INDEX, overweight is defined as having a BMI of 25.0-29.9 kg/m2. Overweight may or may not be due to increases in body fat (ADIPOSE TISSUE), hence overweight does not equal over fat.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (100.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Mastrobattista, JM | 1 |
Klebanoff, MA | 1 |
Carey, JC | 1 |
Hauth, JC | 1 |
Macpherson, CA | 1 |
Ernest, J | 1 |
Cotroneo, M | 1 |
Leveno, KJ | 1 |
Wapner, R | 1 |
Varner, M | 1 |
Iams, JD | 1 |
Moawad, A | 1 |
Sibai, BM | 1 |
Miodovnik, M | 1 |
Dombrowski, M | 1 |
O'Sullivan, MJ | 1 |
Vandorsten, JP | 1 |
Langer, O | 1 |
1 other study available for metronidazole and Overweight
Article | Year |
---|---|
The effect of body mass index on therapeutic response to bacterial vaginosis in pregnancy.
Topics: Adult; Antiprotozoal Agents; Body Mass Index; Female; Humans; Metronidazole; Obesity, Morbid; Overwe | 2008 |