metronidazole has been researched along with Otitis Media, Purulent in 7 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We describe a case of necrobacillosis in a previously healthy child who developed purulent otitis media with sepsis caused by F." | 1.29 | Necrobacillosis: an unusual cause of purulent otitis media and sepsis. ( Cron, RQ; Webb, KH, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Angelino, G | 1 |
| Cantarutti, N | 1 |
| Chiurchiù, S | 1 |
| Amodio, D | 1 |
| De Luca, M | 1 |
| Lancella, L | 1 |
| Coltella, L | 1 |
| Russo, C | 1 |
| Finocchi, A | 1 |
| Marchiori, C | 1 |
| Tonon, E | 1 |
| Boscolo Rizzo, P | 1 |
| Vaglia, A | 1 |
| Meyding-Lamadé, U | 1 |
| Levorato, M | 1 |
| Da Mosto, MC | 1 |
| Dietz, A | 1 |
| Ching, HY | 1 |
| Ramsden, JD | 1 |
| Bottrill, I | 1 |
| Beeden, AG | 1 |
| Willis, AT | 1 |
| Cron, RQ | 1 |
| Webb, KH | 1 |
| Commins, DJ | 1 |
| Koay, B | 1 |
| Milford, CA | 1 |
| Renowden, S | 1 |
| Pace-Balzan, A | 1 |
| Keith, AO | 1 |
| Curley, JW | 1 |
| Ramsden, RT | 1 |
| Lewis, H | 1 |
7 other studies available for metronidazole and Otitis Media, Purulent
| Article | Year |
|---|---|
Fulminant Fusobacterium necrophorum meningitis in an immunocompetent adolescent.
Topics: Adolescent; Anti-Bacterial Agents; Fusobacterium Infections; Fusobacterium necrophorum; Humans; Immu | 2012 |
[Brain abscesses after extracranial infections of the head and neck area].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotic | 2003 |
A unique presentation: Bezold's abscess and glomerulonephritis.
Topics: Abscess; Adolescent; Anti-Infective Agents; Ceftriaxone; Drainage; Glomerulonephritis; Humans; Male; | 2006 |
A case of anaerobic middle ear infection with complications.
Topics: Bacterial Infections; Brain Abscess; Child; Humans; Male; Metronidazole; Otitis Media; Otitis Media, | 1980 |
Necrobacillosis: an unusual cause of purulent otitis media and sepsis.
Topics: Anti-Infective Agents; Child, Preschool; Drug Therapy, Combination; Female; Fusobacterium Infections | 1995 |
Otitic hydrocephalus.
Topics: Anti-Bacterial Agents; Antitrichomonal Agents; Cefotaxime; Cephalosporins; Child; Humans; Hydrocepha | 1997 |
Otogenic Fusobacterium necrophorum meningitis.
Topics: Acute Disease; Child, Preschool; Chloramphenicol; Drug Therapy, Combination; Female; Fusobacterium I | 1991 |