metronidazole has been researched along with Odontalgia in 1 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nagata, JY | 1 |
| Gomes, BP | 1 |
| Rocha Lima, TF | 1 |
| Murakami, LS | 1 |
| de Faria, DE | 1 |
| Campos, GR | 1 |
| de Souza-Filho, FJ | 1 |
| Soares, Ade J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized Controlled Research of the Application of Triple Antibiotic Paste in Primary Teeth With[NCT02196740] | 100 participants (Anticipated) | Interventional | 2013-06-30 | Active, not recruiting | |||
| Clinical and Microbiological Evaluation of a Series of Clinical Cases of Permanent Teeth With Incomplete Apexogenesis and Traumatic Necrosis, Treated With Double Antimicrobial Paste, Revascularization Procedures, and MTA[NCT03112291] | 14 participants (Actual) | Interventional | 2011-11-25 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for metronidazole and Odontalgia
| Article | Year |
|---|---|
Traumatized immature teeth treated with 2 protocols of pulp revascularization.
Topics: Adolescent; Anti-Bacterial Agents; Anti-Infective Agents, Local; Apexification; Calcium Hydroxide; C | 2014 |
Traumatized immature teeth treated with 2 protocols of pulp revascularization.
Topics: Adolescent; Anti-Bacterial Agents; Anti-Infective Agents, Local; Apexification; Calcium Hydroxide; C | 2014 |
Traumatized immature teeth treated with 2 protocols of pulp revascularization.
Topics: Adolescent; Anti-Bacterial Agents; Anti-Infective Agents, Local; Apexification; Calcium Hydroxide; C | 2014 |
Traumatized immature teeth treated with 2 protocols of pulp revascularization.
Topics: Adolescent; Anti-Bacterial Agents; Anti-Infective Agents, Local; Apexification; Calcium Hydroxide; C | 2014 |