metronidazole has been researched along with Neurocysticercosis in 2 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Neurocysticercosis: Infection of the brain, spinal cord, or perimeningeal structures with the larval forms of the genus TAENIA (primarily T. solium in humans). Lesions formed by the organism are referred to as cysticerci. The infection may be subacute or chronic, and the severity of symptoms depends on the severity of the host immune response and the location and number of lesions. SEIZURES represent the most common clinical manifestation although focal neurologic deficits may occur. (From Joynt, Clinical Neurology, 1998, Ch27, pp46-50)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Neurocysticercosis is the commonest CNS parasitic disease worldwide but cysticercal meningitis and intraventricular lesions are relatively rare, especially in Indian patients." | 1.35 | Intraventricular neurocysticercosis. ( Garg, A; Kalra, V; Mishra, D; Seth, R; Suri, A, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kalra, V | 1 |
| Mishra, D | 1 |
| Suri, A | 1 |
| Seth, R | 1 |
| Garg, A | 1 |
| Homans, J | 1 |
| Khoo, L | 1 |
| Chen, T | 1 |
| Commins, DL | 1 |
| Ahmed, J | 1 |
| Kovacs, A | 1 |
1 review available for metronidazole and Neurocysticercosis
| Article | Year |
|---|---|
Spinal intramedullary cysticercosis in a five-year-old child: case report and review of the literature.
Topics: Anti-Bacterial Agents; Antitubercular Agents; Child, Preschool; Drug Therapy, Combination; Female; F | 2001 |
1 other study available for metronidazole and Neurocysticercosis
| Article | Year |
|---|---|
Intraventricular neurocysticercosis.
Topics: Anti-Bacterial Agents; Antifungal Agents; Ceftriaxone; Cerebral Ventricles; Child; Female; Humans; M | 2009 |