metronidazole has been researched along with Neuritis in 2 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Neuritis: A general term indicating inflammation of a peripheral or cranial nerve. Clinical manifestation may include PAIN; PARESTHESIAS; PARESIS; or HYPESTHESIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cerebellar syndrome or seizures are less frequently reported." | 5.35 | [Metronidazole-related polyneuritis, convulsive seizures, and cerebellar syndrome. Contribution of MRI]. ( Corpechot, C; Ferroir, JP; Freudenreich, A; Khalil, A, 2009) |
| "Cerebellar syndrome or seizures are less frequently reported." | 1.35 | [Metronidazole-related polyneuritis, convulsive seizures, and cerebellar syndrome. Contribution of MRI]. ( Corpechot, C; Ferroir, JP; Freudenreich, A; Khalil, A, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ferroir, JP | 1 |
| Corpechot, C | 1 |
| Freudenreich, A | 1 |
| Khalil, A | 1 |
| Sevy, A | 1 |
| Moyse, E | 1 |
| Million, M | 1 |
| Battaglia, F | 1 |
2 other studies available for metronidazole and Neuritis
| Article | Year |
|---|---|
[Metronidazole-related polyneuritis, convulsive seizures, and cerebellar syndrome. Contribution of MRI].
Topics: Aged; Cerebellar Diseases; Cerebellum; Epilepsies, Myoclonic; Humans; Liver Transplantation; Magneti | 2009 |
Central and peripheral neurotoxicity of metronidazole after treatment for brain abscess.
Topics: Anti-Infective Agents; Brain Abscess; Encephalitis; Humans; Male; Metronidazole; Neuritis; Young Adu | 2011 |