metronidazole has been researched along with Myositis in 7 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Myositis: Inflammation of a muscle or muscle tissue.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We present three cases of toxic shock syndrome secondary to (GAS) myositis demonstrating the importance of early recognition and provision of intensive care management." | 1.31 | Toxic shock syndrome and streptococcal myositis: three case reports. ( Vyas, H; Watkins, R, 2002) |
| "Infectious myositis is rather uncommon." | 1.29 | Veillonella myositis in an immunocompromised patient. ( Beumont, MG; Duncan, J; Edelstein, PH; Esterhai, JL; Mitchell, SD, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Watkins, R | 1 |
| Vyas, H | 1 |
| Stewart, AJ | 1 |
| Stevens, DL | 1 |
| Bryant, AE | 1 |
| Adams, K | 1 |
| Mader, JT | 1 |
| Thom, S | 1 |
| Heimbach, D | 1 |
| Beumont, MG | 1 |
| Duncan, J | 1 |
| Mitchell, SD | 1 |
| Esterhai, JL | 1 |
| Edelstein, PH | 1 |
| Finegold, SM | 1 |
| Rosenblatt, JE | 1 |
1 review available for metronidazole and Myositis
| Article | Year |
|---|---|
A role for hyperbaric oxygen in clostridial myonecrosis.
Topics: Animals; Combined Modality Therapy; Gas Gangrene; Hyperbaric Oxygenation; Metronidazole; Mice; Myosi | 1993 |
6 other studies available for metronidazole and Myositis
| Article | Year |
|---|---|
Toxic shock syndrome and streptococcal myositis: three case reports.
Topics: Anti-Bacterial Agents; Child, Preschool; Clindamycin; Critical Care; Female; Humans; Immunoglobulins | 2002 |
Clostridial myositis and collapse in a standardbred filly.
Topics: Abscess; Analgesics; Animals; Anti-Infective Agents; Blood Cell Count; Blood Chemical Analysis; Buto | 2006 |
Evaluation of therapy with hyperbaric oxygen for experimental infection with Clostridium perfringens.
Topics: Animals; Clindamycin; Clostridium perfringens; Dose-Response Relationship, Immunologic; Female; Gas | 1993 |
Use of hyperbaric oxygen.
Topics: Animals; Clindamycin; Combined Modality Therapy; Gas Gangrene; Hyperbaric Oxygenation; Metronidazole | 1993 |
Veillonella myositis in an immunocompromised patient.
Topics: Anti-Bacterial Agents; Combined Modality Therapy; Female; Gram-Negative Bacterial Infections; Humans | 1995 |
Practical aspects of anaerobic sepsis.
Topics: Abscess; Anaerobiosis; Arthritis, Infectious; Bacterial Infections; Bacteroides; Bone Diseases; Brai | 1973 |