metronidazole has been researched along with Mucositis, Oral in 8 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The cyclosporine dosage interval was lengthened over time." | 5.91 | Medical Management of Canine Chronic Ulcerative Stomatitis Using Cyclosporine and Metronidazole. ( Anderson, JG; Archer, T; Ford, KR; Kumar, TKS; Mackin, AJ; Murphy, BG; Stapleton, BL; Wills, RW, 2023) |
| " The cyclosporine dosage interval was lengthened over time." | 1.91 | Medical Management of Canine Chronic Ulcerative Stomatitis Using Cyclosporine and Metronidazole. ( Anderson, JG; Archer, T; Ford, KR; Kumar, TKS; Mackin, AJ; Murphy, BG; Stapleton, BL; Wills, RW, 2023) |
| "Necrotizing stomatitis is more commonly encountered in malnourished children in developing countries, and may subsequently result in devastating facial defects and death." | 1.33 | Necrotizing stomatitis in the developed world. ( Buchanan, JA; Cedro, M; Hodgson, TA; Joseph, T; Mirdin, A; Porter, SR, 2006) |
| "Cancrum oris is predominantly seen in children in underdeveloped countries where widespread malnutrition, dehydration and epidemic infections are present." | 1.28 | Cancrum oris-like lesions. ( Cheng, LH; Nash, ES; Smart, K, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Ford, KR | 1 |
| Anderson, JG | 1 |
| Stapleton, BL | 1 |
| Murphy, BG | 1 |
| Kumar, TKS | 1 |
| Archer, T | 1 |
| Mackin, AJ | 1 |
| Wills, RW | 1 |
| Buchanan, JA | 1 |
| Cedro, M | 1 |
| Mirdin, A | 1 |
| Joseph, T | 1 |
| Porter, SR | 1 |
| Hodgson, TA | 1 |
| Adamek, RJ | 1 |
| Szymanski, C | 1 |
| Pfaffenbach, B | 1 |
| Opferkuch, W | 1 |
| Ricken, D | 1 |
| Wegener, M | 1 |
| Storring, RA | 1 |
| Gerken, ME | 1 |
| Baines, EJ | 1 |
| Nash, ES | 1 |
| Cheng, LH | 1 |
| Smart, K | 1 |
| Luger, A | 1 |
| Lacour, M | 1 |
| Grappin, G | 1 |
1 review available for metronidazole and Mucositis, Oral
| Article | Year |
|---|---|
Metronidazole: its past, present and future.
Topics: Anaerobiosis; Bacterial Infections; Crohn Disease; Dracunculiasis; Humans; Kinetics; Metronidazole; | 1978 |
1 trial available for metronidazole and Mucositis, Oral
| Article | Year |
|---|---|
[Short-term triple therapy with pantoprazole, clarithromycin and metronidazole for the healing of Helicobacter pylori infection].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Aged, 80 and over; Benzimidazoles; Biopsy; Clarithrom | 1995 |
6 other studies available for metronidazole and Mucositis, Oral
| Article | Year |
|---|---|
Medical Management of Canine Chronic Ulcerative Stomatitis Using Cyclosporine and Metronidazole.
Topics: Animals; Cyclosporine; Dog Diseases; Dogs; Immunosuppressive Agents; Interleukin-2; Metronidazole; P | 2023 |
Necrotizing stomatitis in the developed world.
Topics: Aged; Analgesics; Debridement; Deglutition Disorders; Developed Countries; Dietary Supplements; Ging | 2006 |
Letter: Mucosal ulcers and anaerobic organisms.
Topics: Adult; Anaerobiosis; Bacteria; Clindamycin; Humans; Leukemia, Myeloid, Acute; Metronidazole; Mouth M | 1975 |
Cancrum oris-like lesions.
Topics: Ampicillin; Busulfan; Candida albicans; Chronic Disease; Diagnosis, Differential; Disease Susceptibi | 1991 |
[Syphilis diagnosis in the age of antibiotics].
Topics: Adult; Aged; Alopecia; Anti-Bacterial Agents; Balanitis; Biopsy; Child; Child, Preschool; Chloramphe | 1971 |
[Treatment of ulcerous gingivo-stomatitis by metronidazole].
Topics: Child, Preschool; Gingival Diseases; Humans; Infant; Male; Metronidazole; Stomatitis | 1968 |