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metronidazole and Movement Disorders

metronidazole has been researched along with Movement Disorders in 3 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Movement Disorders: Syndromes which feature DYSKINESIAS as a cardinal manifestation of the disease process. Included in this category are degenerative, hereditary, post-infectious, medication-induced, post-inflammatory, and post-traumatic conditions.

Research Excerpts

ExcerptRelevanceReference
"In this case of painful legs and moving toes the essential characteristics were to be secondary to a neuropathy due to vincristine and metronidazole."3.67[Painful legs and moving toes. A drug-induced case]. ( Gastaut, JL, 1986)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Galvez, M1
Brahm, J1
Miranda, M1
Gastaut, JL1
Datta, DV1
Singh, SA1
Chhuttani, PN1

Trials

1 trial available for metronidazole and Movement Disorders

ArticleYear
Treatment of amebic liver abscess with emetine hydrochloride, niridazole, and metronidazole. A controlled clinical trial.
    The American journal of tropical medicine and hygiene, 1974, Volume: 23, Issue:4

    Topics: Adult; Chloroquine; Clinical Trials as Topic; Drug Therapy, Combination; Emetine; Hallucinations; Hu

1974

Other Studies

2 other studies available for metronidazole and Movement Disorders

ArticleYear
Movement disorders as a manifestation of metronidazole-induced encephalopathy in a patient with chronic liver disease.
    Movement disorders : official journal of the Movement Disorder Society, 2009, Sep-15, Volume: 24, Issue:12

    Topics: Anti-Infective Agents; Brain Diseases; Chronic Disease; Diffusion Magnetic Resonance Imaging; Humans

2009
[Painful legs and moving toes. A drug-induced case].
    Revue neurologique, 1986, Volume: 142, Issue:6-7

    Topics: Adult; Drug Interactions; Humans; Leg; Male; Metronidazole; Movement Disorders; Pain; Peripheral Ner

1986