metronidazole has been researched along with Movement Disorders in 3 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Movement Disorders: Syndromes which feature DYSKINESIAS as a cardinal manifestation of the disease process. Included in this category are degenerative, hereditary, post-infectious, medication-induced, post-inflammatory, and post-traumatic conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this case of painful legs and moving toes the essential characteristics were to be secondary to a neuropathy due to vincristine and metronidazole." | 3.67 | [Painful legs and moving toes. A drug-induced case]. ( Gastaut, JL, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Galvez, M | 1 |
| Brahm, J | 1 |
| Miranda, M | 1 |
| Gastaut, JL | 1 |
| Datta, DV | 1 |
| Singh, SA | 1 |
| Chhuttani, PN | 1 |
1 trial available for metronidazole and Movement Disorders
| Article | Year |
|---|---|
Treatment of amebic liver abscess with emetine hydrochloride, niridazole, and metronidazole. A controlled clinical trial.
Topics: Adult; Chloroquine; Clinical Trials as Topic; Drug Therapy, Combination; Emetine; Hallucinations; Hu | 1974 |
2 other studies available for metronidazole and Movement Disorders
| Article | Year |
|---|---|
Movement disorders as a manifestation of metronidazole-induced encephalopathy in a patient with chronic liver disease.
Topics: Anti-Infective Agents; Brain Diseases; Chronic Disease; Diffusion Magnetic Resonance Imaging; Humans | 2009 |
[Painful legs and moving toes. A drug-induced case].
Topics: Adult; Drug Interactions; Humans; Leg; Male; Metronidazole; Movement Disorders; Pain; Peripheral Ner | 1986 |