metronidazole has been researched along with Mouth Ulcer in 4 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (25.00) | 29.6817 |
2010's | 2 (50.00) | 24.3611 |
2020's | 1 (25.00) | 2.80 |
Authors | Studies |
---|---|
Brotherton, BJ | 1 |
Thermos, G | 1 |
Tosios, KI | 1 |
Paramkusam, G | 1 |
Meduri, V | 1 |
Gangeshetty, N | 1 |
Siegel, MA | 1 |
Migliorati, CA | 1 |
Velez, I | 1 |
Forrest, M | 1 |
1 review available for metronidazole and Mouth Ulcer
Article | Year |
---|---|
Pyoderma gangrenosum with oral involvement - case report and review of the literature.
Topics: Adult; Anti-Infective Agents; Chlorhexidine; Dapsone; Drug Therapy, Combination; Female; Glucocortic | 2010 |
3 other studies available for metronidazole and Mouth Ulcer
Article | Year |
---|---|
Visual Diagnosis: Rapidly Progressing Oral Ulcer in a 13-year-old Girl.
Topics: Adolescent; Anti-Bacterial Agents; Debridement; Diagnosis, Differential; Female; Humans; Metronidazo | 2019 |
Ibrutinib-associated oral ulcers.
Topics: Adenine; Aged; Combined Modality Therapy; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Metr | 2020 |
Exposed bone in the palate.
Topics: Aged, 80 and over; Anti-Infective Agents, Local; Bone Density Conservation Agents; Chlorhexidine; Cl | 2007 |