metronidazole has been researched along with Mastitis in 6 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Mastitis: INFLAMMATION of the BREAST, or MAMMARY GLAND.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pathogenic anaerobic bacteria may be among the causes of puerperal mastitis which, therefore, was treated by the authors with metronidazole (Vagimid) and with antibiotics, such as penicillin, oxacillin, erythromycin, and oxytetracycline." | 7.66 | [Metronidazole for treatment of puerperal mastitis (author's transl)]. ( Amon, I; Amon, K; Scharp, H, 1982) |
| "We report the first case of an infected breast cyst in a non-puerperal women due to this pathogen." | 5.46 | Infected breast cyst due to Prevotella buccae resistant to metronidazole. ( Cobo, F; Navarro-Marí, JM; Rodríguez-Granger, J; Sampedro, A, 2017) |
| "Pathogenic anaerobic bacteria may be among the causes of puerperal mastitis which, therefore, was treated by the authors with metronidazole (Vagimid) and with antibiotics, such as penicillin, oxacillin, erythromycin, and oxytetracycline." | 3.66 | [Metronidazole for treatment of puerperal mastitis (author's transl)]. ( Amon, I; Amon, K; Scharp, H, 1982) |
| "When endometritis has been identified and cultures from the genital tract obtained." | 2.42 | Postpartum infection treatments: a review. ( Burstein, E; Chaim, W, 2003) |
| "We report the first case of an infected breast cyst in a non-puerperal women due to this pathogen." | 1.46 | Infected breast cyst due to Prevotella buccae resistant to metronidazole. ( Cobo, F; Navarro-Marí, JM; Rodríguez-Granger, J; Sampedro, A, 2017) |
| "Non puerperal mastitis is an inflammatory disease that resembles carcinoma, the course is insidious and frequently this entity is misdiagnosed." | 1.29 | [Non-puerperal mastitis. Clinical study of 30 patients]. ( Moreno, G; Paredes López, A, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cobo, F | 1 |
| Rodríguez-Granger, J | 1 |
| Sampedro, A | 1 |
| Navarro-Marí, JM | 1 |
| Harji, DP | 1 |
| Rastall, S | 1 |
| Catchpole, C | 1 |
| Bright-Thomas, R | 1 |
| Thrush, S | 1 |
| Chaim, W | 1 |
| Burstein, E | 1 |
| Amon, K | 1 |
| Amon, I | 1 |
| Scharp, H | 1 |
| Paredes López, A | 1 |
| Moreno, G | 1 |
| Leach, RD | 1 |
| Eykyn, SJ | 1 |
| Phillips, I | 1 |
| Corrin, B | 1 |
2 reviews available for metronidazole and Mastitis
| Article | Year |
|---|---|
Pseudomonal breast infection.
Topics: Abscess; Anti-Bacterial Agents; Ciprofloxacin; Drug Therapy, Combination; Female; Humans; Mastitis; | 2010 |
Postpartum infection treatments: a review.
Topics: 4-Quinolones; Adult; Aminoglycosides; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infect | 2003 |
4 other studies available for metronidazole and Mastitis
| Article | Year |
|---|---|
Infected breast cyst due to Prevotella buccae resistant to metronidazole.
Topics: Abscess; Bacteroidaceae Infections; Breast Cyst; Combined Modality Therapy; Drainage; Drug Resistanc | 2017 |
[Metronidazole for treatment of puerperal mastitis (author's transl)].
Topics: Anti-Bacterial Agents; Female; Humans; Mastitis; Metronidazole; Milk, Human; Pregnancy; Puerperal Di | 1982 |
[Non-puerperal mastitis. Clinical study of 30 patients].
Topics: Adenocarcinoma; Adult; Aged; Breast Neoplasms; Diagnosis, Differential; Erythromycin; Female; Humans | 1995 |
Anaerobic subareolar breast abscess.
Topics: Abscess; Adult; Ampicillin; Bacteroides; Bacteroides Infections; Drainage; Female; Humans; Mastitis; | 1979 |