metronidazole has been researched along with Macular Edema in 1 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Macular Edema: Fluid accumulation in the outer layer of the MACULA LUTEA that results from intraocular or systemic insults. It may develop in a diffuse pattern where the macula appears thickened or it may acquire the characteristic petaloid appearance referred to as cystoid macular edema. Although macular edema may be associated with various underlying conditions, it is most commonly seen following intraocular surgery, venous occlusive disease, DIABETIC RETINOPATHY, and posterior segment inflammatory disease. (From Survey of Ophthalmology 2004; 49(5) 470-90)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Orbital cellulitis is a serious sight threatening and potentially life threatening condition which can be complicated by orbital abscess formation." | 5.46 | Orbital abscess following posterior subtenon injection of triamcinolone acetonide. ( Connell, P; Fulcher, T; McAnena, L; McElnea, E; Rhatigan, M, 2017) |
| "Orbital cellulitis is a serious sight threatening and potentially life threatening condition which can be complicated by orbital abscess formation." | 1.46 | Orbital abscess following posterior subtenon injection of triamcinolone acetonide. ( Connell, P; Fulcher, T; McAnena, L; McElnea, E; Rhatigan, M, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rhatigan, M | 1 |
| McAnena, L | 1 |
| McElnea, E | 1 |
| Connell, P | 1 |
| Fulcher, T | 1 |
1 other study available for metronidazole and Macular Edema
| Article | Year |
|---|---|
Orbital abscess following posterior subtenon injection of triamcinolone acetonide.
Topics: Abscess; Anti-Bacterial Agents; Ceftriaxone; Drug Therapy, Combination; Floxacillin; Glucocorticoids | 2017 |