metronidazole has been researched along with Lymphoma in 6 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Lymphoma: A general term for various neoplastic diseases of the lymphoid tissue.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a single-center open-label prospective study, a total of 134 marrow transplant recipients with hematologic malignancies were randomly assigned to a bacterial decontamination medication using metronidazole and ciprofloxacin (n = 68) or ciprofloxacin alone (n = 66) during 5 weeks posttransplant." | 9.09 | Influence of intestinal bacterial decontamination using metronidazole and ciprofloxacin or ciprofloxacin alone on the development of acute graft-versus-host disease after marrow transplantation in patients with hematologic malignancies: final results and ( Beelen, DW; Elmaagacli, A; Hirche, H; Müller, KD; Schaefer, UW, 1999) |
| "In a single-center open-label prospective study, a total of 134 marrow transplant recipients with hematologic malignancies were randomly assigned to a bacterial decontamination medication using metronidazole and ciprofloxacin (n = 68) or ciprofloxacin alone (n = 66) during 5 weeks posttransplant." | 5.09 | Influence of intestinal bacterial decontamination using metronidazole and ciprofloxacin or ciprofloxacin alone on the development of acute graft-versus-host disease after marrow transplantation in patients with hematologic malignancies: final results and ( Beelen, DW; Elmaagacli, A; Hirche, H; Müller, KD; Schaefer, UW, 1999) |
| "Treatment with metronidazole induced the disappearance of coccidia from the stool and clinical remission." | 1.26 | Malabsorption syndrome, coccidiosis, combined immune deficiency, and fulminant lymphoproliferative disease. ( Adar, U; Hallak, A; Ratan, Y; Yust, I, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Das, T | 1 |
| Banerjee, S | 1 |
| Samuel, G | 1 |
| Sarma, HD | 1 |
| Korde, A | 1 |
| Venkatesh, M | 1 |
| Pillai, MR | 1 |
| Sawatzki, M | 1 |
| Peter, S | 1 |
| Hess, C | 1 |
| Cavaliere, A | 1 |
| Bacci, M | 1 |
| Amorosi, A | 1 |
| Del Gaudio, M | 1 |
| Vitali, R | 1 |
| Hallak, A | 1 |
| Yust, I | 1 |
| Ratan, Y | 1 |
| Adar, U | 1 |
| Barrett, AP | 1 |
| Schifter, M | 1 |
| Beelen, DW | 1 |
| Elmaagacli, A | 1 |
| Müller, KD | 1 |
| Hirche, H | 1 |
| Schaefer, UW | 1 |
1 trial available for metronidazole and Lymphoma
| Article | Year |
|---|---|
Influence of intestinal bacterial decontamination using metronidazole and ciprofloxacin or ciprofloxacin alone on the development of acute graft-versus-host disease after marrow transplantation in patients with hematologic malignancies: final results and
Topics: Adolescent; Adult; Anti-Bacterial Agents; Bone Marrow Transplantation; Ciprofloxacin; Drug Therapy, | 1999 |
5 other studies available for metronidazole and Lymphoma
| Article | Year |
|---|---|
99mTc-labeling studies of a modified metronidazole and its biodistribution in tumor bearing animal models.
Topics: Animals; Female; Isotope Labeling; Lymphoma; Metabolic Clearance Rate; Metronidazole; Mice; Neoplasm | 2003 |
Therapy-resistant diarrhea due to Giardia lamblia in a patient with common variable immunodeficiency disease.
Topics: Albendazole; Animals; Antiprotozoal Agents; Common Variable Immunodeficiency; Diagnosis, Differentia | 2007 |
Induction of lung tumors and lymphomas in BALB/c mice by metronidazole.
Topics: Animals; Female; Lung Neoplasms; Lymphoma; Male; Metronidazole; Mice; Mice, Inbred BALB C; Sex Facto | 1983 |
Malabsorption syndrome, coccidiosis, combined immune deficiency, and fulminant lymphoproliferative disease.
Topics: Adult; Coccidiosis; Humans; Immunologic Deficiency Syndromes; Lymphoma; Malabsorption Syndromes; Mal | 1982 |
Antibiotic strategy in orofacial/head and neck infections in severe neutropenia.
Topics: Adolescent; Adult; Aged; Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Clinical Prot | 1994 |