metronidazole has been researched along with Lymph Node Metastasis in 7 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The results of radiation therapy were compared in 217 patients at advanced stages of cancer of the tongue (131) and fundus of the mouth (86) using split courses of conventional (SCF) and dynamic fractionation (SDF) and SDF combined with metronidazole." | 3.68 | [Probit analysis in assessing the results of radiation therapy of disseminated cancer of the tongue and floor of the mouth]. ( Limarova, IV; Ustinskov, VI; Vorob'ev, IuI, 1990) |
| "The patient received treatment with anti-tetanus globulin and metronidazole; sound insulation and shielding were also performed in a dark room." | 2.72 | Non-surgical treatment of tetanus infection associated with breast cancer skin ulcer: a case report and literature review. ( Aisaka, W; Narimatsu, E; Nomura, K; Okamoto, H; Sakawaki, E; Sakawaki, S; Takeyama, Y; Uemura, S; Yamaoka, A, 2021) |
| "Metronidazole was administered per os 3 = 4 h before irradiation with fractions I, III and V of each phase of a split course." | 1.27 | [Radiotherapy, using metronidazole, of regional lymph node metastases of cancer of the oral mucosa]. ( Limarova, IV, 1986) |
| "The results of combined treatment of 98 laryngeal cancer patients followed up for 1." | 1.27 | [Combined (radiation and surgical) treatment of laryngeal cancer patients using metronidazole]. ( Andreev, VG, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Nomura, K | 1 |
| Sakawaki, E | 1 |
| Sakawaki, S | 1 |
| Yamaoka, A | 1 |
| Aisaka, W | 1 |
| Okamoto, H | 1 |
| Takeyama, Y | 1 |
| Uemura, S | 1 |
| Narimatsu, E | 1 |
| Aebischer, B | 1 |
| Elsig, S | 1 |
| Taeymans, J | 1 |
| Pomp, S | 1 |
| Kuhness, D | 1 |
| Barcaro, G | 1 |
| Sementa, L | 1 |
| Mankad, V | 1 |
| Fortunelli, A | 1 |
| Sterrer, M | 1 |
| Netzer, FP | 1 |
| Surnev, S | 1 |
| Schmieder, AH | 1 |
| Caruthers, SD | 1 |
| Keupp, J | 1 |
| Wickline, SA | 1 |
| Lanza, GM | 1 |
| Lowe, J | 1 |
| Wodarcyk, AJ | 1 |
| Floyd, KT | 1 |
| Rastogi, N | 1 |
| Schultz, EJ | 1 |
| Swager, SA | 1 |
| Chadwick, JA | 1 |
| Tran, T | 1 |
| Raman, SV | 1 |
| Janssen, PM | 1 |
| Rafael-Fortney, JA | 1 |
| Alcalay, RN | 1 |
| Levy, OA | 1 |
| Wolf, P | 1 |
| Oliva, P | 1 |
| Zhang, XK | 1 |
| Waters, CH | 1 |
| Fahn, S | 1 |
| Kang, U | 1 |
| Liong, C | 1 |
| Ford, B | 1 |
| Mazzoni, P | 1 |
| Kuo, S | 1 |
| Johnson, A | 1 |
| Xiong, L | 1 |
| Rouleau, GA | 1 |
| Chung, W | 1 |
| Marder, KS | 1 |
| Gan-Or, Z | 1 |
| Kamei, K | 1 |
| Terao, T | 1 |
| Katayama, Y | 1 |
| Hatano, K | 1 |
| Kodama, K | 1 |
| Shirahama, M | 1 |
| Sakai, A | 1 |
| Hirakawa, H | 1 |
| Mizokami, Y | 1 |
| Shiotsuki, I | 1 |
| Ishii, N | 1 |
| Inoue, Y | 1 |
| Akboga, MK | 1 |
| Yayla, C | 1 |
| Balci, KG | 1 |
| Ozeke, O | 1 |
| Maden, O | 1 |
| Kisacik, H | 1 |
| Temizhan, A | 1 |
| Aydogdu, S | 1 |
| Zhu, J | 2 |
| Ying, SH | 1 |
| Feng, MG | 1 |
| Zhang, XG | 1 |
| Li, H | 1 |
| Wang, L | 1 |
| Hao, YY | 1 |
| Liang, GD | 1 |
| Ma, YH | 1 |
| Yang, GS | 1 |
| Hu, JH | 1 |
| Pfeifer, L | 1 |
| Goertz, RS | 1 |
| Neurath, MF | 1 |
| Strobel, D | 1 |
| Wildner, D | 1 |
| Lin, JT | 1 |
| Yang, XN | 1 |
| Zhong, WZ | 1 |
| Liao, RQ | 1 |
| Dong, S | 1 |
| Nie, Q | 1 |
| Weng, SX | 1 |
| Fang, XJ | 1 |
| Zheng, JY | 1 |
| Wu, YL | 1 |
| Řezanka, T | 1 |
| Kaineder, K | 1 |
| Mezricky, D | 1 |
| Řezanka, M | 1 |
| Bišová, K | 1 |
| Zachleder, V | 1 |
| Vítová, M | 1 |
| Rinker, JA | 1 |
| Marshall, SA | 1 |
| Mazzone, CM | 1 |
| Lowery-Gionta, EG | 1 |
| Gulati, V | 1 |
| Pleil, KE | 1 |
| Kash, TL | 1 |
| Navarro, M | 1 |
| Thiele, TE | 1 |
| Zhang, Y | 1 |
| Huang, Y | 1 |
| Jin, Z | 1 |
| Li, X | 1 |
| Li, B | 1 |
| Xu, P | 1 |
| Huang, P | 1 |
| Liu, C | 1 |
| Fokdal, L | 1 |
| Sturdza, A | 1 |
| Mazeron, R | 1 |
| Haie-Meder, C | 1 |
| Tan, LT | 1 |
| Gillham, C | 1 |
| Šegedin, B | 1 |
| Jürgenliemk-Schultz, I | 1 |
| Kirisits, C | 1 |
| Hoskin, P | 1 |
| Pötter, R | 1 |
| Lindegaard, JC | 1 |
| Tanderup, K | 1 |
| Levin, DE | 1 |
| Schmitz, AJ | 1 |
| Hines, SM | 1 |
| Hines, KJ | 1 |
| Tucker, MJ | 1 |
| Brewer, SH | 1 |
| Fenlon, EE | 1 |
| Álvarez-Pérez, S | 1 |
| Blanco, JL | 1 |
| Peláez, T | 1 |
| Martínez-Nevado, E | 1 |
| García, ME | 1 |
| Puckerin, AA | 1 |
| Chang, DD | 1 |
| Subramanyam, P | 1 |
| Colecraft, HM | 1 |
| Dogan, H | 1 |
| Coteli, E | 1 |
| Karatas, F | 1 |
| Ceylan, O | 1 |
| Sahin, MD | 1 |
| Akdamar, G | 1 |
| Kryczyk, A | 1 |
| Żmudzki, P | 1 |
| Hubicka, U | 1 |
| Giovannelli, D | 1 |
| Chung, M | 1 |
| Staley, J | 1 |
| Starovoytov, V | 1 |
| Le Bris, N | 1 |
| Vetriani, C | 1 |
| Chen, W | 1 |
| Wu, L | 1 |
| Liu, X | 1 |
| Shen, Y | 1 |
| Liang, Y | 1 |
| Tan, H | 1 |
| Yang, Y | 1 |
| Liu, Q | 1 |
| Wang, M | 1 |
| Liu, L | 1 |
| Wang, X | 1 |
| Liu, B | 1 |
| Liu, GH | 1 |
| Zhu, YJ | 1 |
| Wang, JP | 1 |
| Che, JM | 1 |
| Chen, QQ | 1 |
| Chen, Z | 1 |
| Maucksch, U | 1 |
| Runge, R | 1 |
| Wunderlich, G | 1 |
| Freudenberg, R | 1 |
| Naumann, A | 1 |
| Kotzerke, J | 1 |
| Tokuyama, H | 1 |
| Higashi, F | 1 |
| Tamaki, H | 1 |
| Kunishoh, T | 1 |
| Tamaki, Y | 1 |
| Kawai, J | 1 |
| Sakatsuji, K | 1 |
| Itoh, H | 1 |
| Nakayama, T | 1 |
| Nishioka, S | 1 |
| Vorob'ev, IuI | 1 |
| Limarova, IV | 2 |
| Ustinskov, VI | 1 |
| Sal'nikov, LV | 1 |
| Mezentsev, AI | 1 |
| Bedrin, LM | 1 |
| Chernova, AS | 1 |
| Andreev, VG | 1 |
3 reviews available for metronidazole and Lymph Node Metastasis
| Article | Year |
|---|---|
Non-surgical treatment of tetanus infection associated with breast cancer skin ulcer: a case report and literature review.
Topics: Breast Neoplasms; Female; Humans; Lymphatic Metastasis; Metronidazole; Middle Aged; Neoplasm Recurre | 2021 |
Topics: AC133 Antigen; Acenaphthenes; Acer; Acrosome Reaction; Adult; Agaricales; Aged; Aged, 80 and over; A | 2016 |
[A case of amebic liver abscess with colonic carcinoma].
Topics: Adenocarcinoma; Female; Humans; Liver Abscess, Amebic; Lymphatic Metastasis; Metronidazole; Middle A | 1993 |
4 other studies available for metronidazole and Lymph Node Metastasis
| Article | Year |
|---|---|
[Probit analysis in assessing the results of radiation therapy of disseminated cancer of the tongue and floor of the mouth].
Topics: Carcinoma, Squamous Cell; Combined Modality Therapy; Dose-Response Relationship, Radiation; Female; | 1990 |
[Direct and immediate results of the radiation and combined treatment of laryngeal cancer with local use of metronidazole].
Topics: Adult; Aged; Biopsy; Combined Modality Therapy; Dimethyl Sulfoxide; Humans; Laryngeal Neoplasms; Lym | 1986 |
[Radiotherapy, using metronidazole, of regional lymph node metastases of cancer of the oral mucosa].
Topics: Aged; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Humans; Lymphatic Metastasis; Mal | 1986 |
[Combined (radiation and surgical) treatment of laryngeal cancer patients using metronidazole].
Topics: Adult; Aged; Carcinoma, Squamous Cell; Combined Modality Therapy; Humans; Laryngeal Neoplasms; Laryn | 1985 |