metronidazole has been researched along with Low Back Pain in 3 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Low Back Pain: Acute or chronic pain in the lumbar or sacral regions, which may be associated with musculo-ligamentous SPRAINS AND STRAINS; INTERVERTEBRAL DISK DISPLACEMENT; and other conditions.
Excerpt | Relevance | Reference |
---|---|---|
"Metronidazole was administrated for 5 weeks and symptoms were completely resolved." | 1.39 | Bacteroides fragilis vertebral osteomyelitis complicated by percutaneous epidural adhesiolysis. ( Choi, BK; Han, IH; Kim, SY; Nam, KH, 2013) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (33.33) | 29.6817 |
2010's | 2 (66.67) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Denes, E | 1 |
Cypierre, A | 1 |
Vacquier, J | 1 |
Matt, M | 1 |
Weinbreck, P | 1 |
Han, IH | 1 |
Choi, BK | 1 |
Nam, KH | 1 |
Kim, SY | 1 |
Chazan, B | 1 |
Strahilevitz, J | 1 |
Millgram, MA | 1 |
Kaufmann, S | 1 |
Raz, R | 1 |
3 other studies available for metronidazole and Low Back Pain
Article | Year |
---|---|
Meningitis due to Fusobacterium nucleatum after a kart crash.
Topics: Anti-Infective Agents; Athletic Injuries; Bacteremia; Bacterial Translocation; Bacterial Typing Tech | 2013 |
Bacteroides fragilis vertebral osteomyelitis complicated by percutaneous epidural adhesiolysis.
Topics: Adult; Anti-Bacterial Agents; Bacteroides fragilis; Bacteroides Infections; Ceftazidime; Combined Mo | 2013 |
Bacteroides fragilis vertebral osteomyelitis secondary to anal dilatation.
Topics: Adolescent; Bacteroides fragilis; Bacteroides Infections; Dilatation; Fissure in Ano; Humans; Low Ba | 2001 |