metronidazole has been researched along with Liver Abscess, Pyogenic in 10 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Liver Abscess, Pyogenic: Single or multiple areas of PUS due to bacterial infection within the hepatic parenchyma. It can be caused by a variety of BACTERIA, local or disseminated from infections elsewhere such as in APPENDICITIS; CHOLECYSTITIS; PERITONITIS; and after LIVER TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amebic liver abscess is caused by extraintestinal spread of Entamoeba histolytica." | 2.66 | Pyogenic and Amebic Infections of the Liver. ( Lisker-Melman, M; Roediger, R, 2020) |
| "This is the first pyogenic liver abscess reported caused by Granulicatella adiacens in an immunocompetent patient, in whom early microbiological diagnosis in conjunction with targeted antibiotic treatment and percutaneous drainage of the lesion was decisive in the clinical outcome." | 1.91 | Liver abscess due to Granulicatella adiacens in an immunocompetent patient: Case report. ( García-Casallas, J; Molina-Ardila, M; Patiño-Salazar, K; Tuta-Quintero, E, 2023) |
| "To review our experience in managing pyogenic liver abscesses to aid in the current management of this complex condition." | 1.46 | Pyogenic Liver Abscess: A Retrospective Study of 105 Cases in an Emergency Department from East China. ( Chen, W; Liu, L; Lu, X; Zhang, K; Zhu, C, 2017) |
| "However, the cases of stomach cancer concomitant with pyogenic liver abscess have rarely been reported in the world." | 1.46 | A Case of Advanced Gastric Cancer Concomitant with Pyogenic Liver Abscess in the Patient with Subtotal Gastrectomy. ( Heo, NY; Jeong, NR; Jeong, SJ; Nam, KH; Oh, SJ; Park, DH; Sa-Kong, H, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 3 (30.00) | 2.80 |
| Authors | Studies |
|---|---|
| García-Casallas, J | 1 |
| Patiño-Salazar, K | 1 |
| Tuta-Quintero, E | 1 |
| Molina-Ardila, M | 1 |
| Schattner, A | 1 |
| Uliel, L | 1 |
| Finn, T | 1 |
| Dubin, I | 1 |
| Roediger, R | 1 |
| Lisker-Melman, M | 1 |
| Karantanos, T | 1 |
| Karanika, S | 1 |
| Obiokoye, K | 1 |
| Sullivan, M | 1 |
| Phillips, C | 1 |
| Ananthakrishnan, S | 1 |
| Recio, R | 1 |
| Brañas, P | 1 |
| Chaves, F | 1 |
| Orellana, MÁ | 1 |
| Kim, HA | 1 |
| Chung, DR | 1 |
| Yeom, JS | 1 |
| Ki, HK | 1 |
| Cheong, HS | 1 |
| Son, JS | 1 |
| Lee, JS | 1 |
| Moon, SY | 1 |
| Lee, SS | 1 |
| Lee, JA | 1 |
| Park, KH | 1 |
| Kang, SJ | 1 |
| Jung, SI | 1 |
| Kim, SW | 1 |
| Chang, HH | 1 |
| Ryu, SY | 1 |
| Kwon, KT | 1 |
| Moon, C | 1 |
| Wi, YM | 1 |
| Heo, ST | 1 |
| Joung, MK | 1 |
| Kang, CI | 1 |
| Peck, KR | 1 |
| Song, JH | 1 |
| Liu, L | 1 |
| Chen, W | 1 |
| Lu, X | 1 |
| Zhang, K | 1 |
| Zhu, C | 1 |
| Park, DH | 1 |
| Heo, NY | 1 |
| Sa-Kong, H | 1 |
| Jeong, NR | 1 |
| Jeong, SJ | 1 |
| Oh, SJ | 1 |
| Nam, KH | 1 |
| Cigarrán, S | 1 |
| Neches, C | 1 |
| Lamas, JM | 1 |
| García-Trio, G | 1 |
| Alonso, M | 1 |
| Saavedra, J | 1 |
| Chung, YF | 1 |
1 review available for metronidazole and Liver Abscess, Pyogenic
| Article | Year |
|---|---|
Pyogenic and Amebic Infections of the Liver.
Topics: Anti-Bacterial Agents; Drainage; Entamoeba histolytica; Humans; Liver Abscess, Amebic; Liver Abscess | 2020 |
1 trial available for metronidazole and Liver Abscess, Pyogenic
| Article | Year |
|---|---|
Anti-anaerobic coverage is not necessary for Klebsiella pneumoniae liver abscess: a propensity score-matched cohort study.
Topics: Aged; Anti-Bacterial Agents; Cohort Studies; Female; Humans; Klebsiella Infections; Klebsiella pneum | 2015 |
8 other studies available for metronidazole and Liver Abscess, Pyogenic
| Article | Year |
|---|---|
Liver abscess due to Granulicatella adiacens in an immunocompetent patient: Case report.
Topics: Adult; Anti-Bacterial Agents; Carnobacteriaceae; Escherichia coli; Humans; Liver Abscess, Pyogenic; | 2023 |
'Giant' pyogenic liver abscess and
Topics: Alcoholism; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Ceftriaxone; Diabe | 2020 |
Pyogenic Liver Abscess Due to Fusobacterium nucleatum in a Patient With Liver Hemangiomas.
Topics: Adult; Fever; Fusobacterium Infections; Fusobacterium nucleatum; Hemangioma; Humans; Liver; Liver Ab | 2017 |
Photo Quiz: Isolation of a "Friendly Bacterium" from a Pyogenic Liver Abscess.
Topics: Aged; Anti-Bacterial Agents; Bacteremia; Ceftriaxone; Gram-Positive Bacteria; Gram-Positive Bacteria | 2018 |
Pyogenic Liver Abscess: A Retrospective Study of 105 Cases in an Emergency Department from East China.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; C-Reactive Protein; Calcitonin; Carbapenems; Cephalo | 2017 |
A Case of Advanced Gastric Cancer Concomitant with Pyogenic Liver Abscess in the Patient with Subtotal Gastrectomy.
Topics: Aged; Anti-Bacterial Agents; Ceftriaxone; Drug Therapy, Combination; Endoscopy, Digestive System; Ga | 2017 |
A case report of a pyogenic liver abscess caused by Fusobacterium nucleatum in a patient with autosomal dominant polycystic kidney disease undergoing hemodialysis.
Topics: Anti-Bacterial Agents; Catheterization; Drainage; Fusobacterium Infections; Fusobacterium nucleatum; | 2008 |
Pyogenic liver abscess--predicting failure to improve outcome.
Topics: Anti-Infective Agents; Humans; Liver Abscess, Pyogenic; Metronidazole; Prognosis; Treatment Outcome | 2008 |