metronidazole has been researched along with Lemierre Disease in 16 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with confirmed Lemierre syndrome were included in our retrospective monocentric study." | 2.50 | Lemierre syndrome: study of 11 cases and literature review. ( Atallah, I; Karkas, A; N'Gouan, JM; Reyt, E; Righini, CA; Schmerber, S; Tourniaire, R, 2014) |
| "We present two cases of Lemierre's syndrome with internal jugular vein thrombophlebitis and positive blood cultures for F." | 1.51 | Lemierre's syndrome: One rare disease-Two case studies. ( Alaev, O; Bryan, A; Gelfman, A; Gennaro, D; Le, C; Marshall, D; Wang, Z, 2019) |
| "Lemierre's syndrome is a condition characterised by suppurative thrombophlebitis of the internal jugular (IJ) vein following a recent oropharyngeal infection, with resulting septicaemia and metastatic lesions." | 1.48 | Lesson of the month 1: Lemierre's syndrome: a reminder of the 'forgotten disease'. ( Fattah, Z; Vijay, V, 2018) |
| "This is a case report of Lemierre's syndrome, a septic thrombophlebitis of the internal jugular vein (IJV) usually preceded by pharyngitis and bacteraemia with an anaerobic organism." | 1.42 | Importance of blood cultures to aid the diagnosis of Lemierre's syndrome. ( Nejat, M; Werno, A, 2015) |
| "An increasingly reported entity, Lemierre's syndrome classically presents with a recent oropharyngeal infection, internal jugular vein thrombosis and the presence of anaerobic organisms such as Fusobacterium necrophorum." | 1.42 | Clival osteomyelitis and hypoglossal nerve palsy--rare complications of Lemierre's syndrome. ( Adlan, T; He, J; Lam, JC, 2015) |
| "Lemierre's syndrome is an often un-diagnosed disease seen in previously healthy young subjects, presenting with symptoms of pharyngitis, fever and elevated markers of inflammation." | 1.40 | Lemierre's syndrome: the forgotten disease. ( Bødtger, U; Heltberg, O; Johannesen, K, 2014) |
| "Lemierre's syndrome is a rare yet potentially fatal cause of sore throat." | 1.39 | Doctor, I have a sore throat. ( Dholakia, S; Hashimi, Y, 2013) |
| "Lemierre's syndrome is a disseminated infection which is usually caused by Fusobacterium necrophorum." | 1.38 | [Lemierre's syndrome as differential diagnosis of lung cancer]. ( Reinholdt Jensen, J; Weinreich, UM, 2012) |
| "We report a case of Lemierre syndrome which was recently diagnosed in our centre." | 1.38 | Lemierre syndrome. ( Lim, AL; Pua, KC, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 14 (87.50) | 24.3611 |
| 2020's | 2 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Panchani, D | 1 |
| Nair, D | 1 |
| Bourgeaud, J | 1 |
| Delabays, B | 1 |
| Van den Bogaart, L | 1 |
| Ratano, D | 1 |
| Chua, SH | 1 |
| Ong, SCL | 1 |
| Liew, YH | 1 |
| Vijay, V | 1 |
| Fattah, Z | 1 |
| Le, C | 1 |
| Gennaro, D | 1 |
| Marshall, D | 1 |
| Alaev, O | 1 |
| Bryan, A | 1 |
| Gelfman, A | 1 |
| Wang, Z | 1 |
| Teh, BM | 1 |
| Gordon, R | 1 |
| Rowe, D | 1 |
| Fuller, A | 1 |
| Jeyarajan, H | 1 |
| Johannesen, K | 1 |
| Bødtger, U | 1 |
| Heltberg, O | 1 |
| Righini, CA | 1 |
| Karkas, A | 1 |
| Tourniaire, R | 1 |
| N'Gouan, JM | 1 |
| Schmerber, S | 1 |
| Reyt, E | 1 |
| Atallah, I | 1 |
| Shiber, J | 1 |
| Fontane, E | 1 |
| Rabinowitz, R | 1 |
| Gens, D | 1 |
| Habashi, N | 1 |
| Scalea, T | 1 |
| Nejat, M | 1 |
| Werno, A | 1 |
| Oya, M | 1 |
| Tanimoto, T | 1 |
| Yamamoto, T | 1 |
| Hakozaki, Y | 1 |
| He, J | 1 |
| Lam, JC | 1 |
| Adlan, T | 1 |
| Kerhuel, L | 1 |
| Valade, S | 1 |
| Donay, JL | 1 |
| Canet, E | 1 |
| Reinholdt Jensen, J | 1 |
| Weinreich, UM | 1 |
| Lim, AL | 1 |
| Pua, KC | 1 |
| Dholakia, S | 1 |
| Hashimi, Y | 1 |
2 reviews available for metronidazole and Lemierre Disease
| Article | Year |
|---|---|
Lemierre syndrome: study of 11 cases and literature review.
Topics: Abscess; Adolescent; Adult; Aged; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agen | 2014 |
Incomplete Lemierre syndrome.
Topics: Adolescent; Ampicillin; Anti-Bacterial Agents; Anti-Infective Agents; Female; Fusobacterium Infectio | 2015 |
14 other studies available for metronidazole and Lemierre Disease
| Article | Year |
|---|---|
Not always as simple as a UTI: An atypical case of Lemierre's syndrome, the forgotten disease.
Topics: Aged; Fusobacterium necrophorum; Humans; Jugular Veins; Lemierre Syndrome; Male; Metronidazole; Tomo | 2021 |
Complex Lemierre syndrome with multisystemic abscesses.
Topics: Anti-Bacterial Agents; Brain Abscess; Ceftriaxone; Female; Fusobacterium Infections; Fusobacterium n | 2023 |
Variant of Lemierre's syndrome with internal jugular vein aneurysm.
Topics: Aneurysm; Anti-Bacterial Agents; Anticoagulants; Ceftriaxone; Enoxaparin; Female; Humans; Jugular Ve | 2017 |
Lesson of the month 1: Lemierre's syndrome: a reminder of the 'forgotten disease'.
Topics: Anti-Bacterial Agents; Drainage; Early Diagnosis; Fusobacterium necrophorum; Humans; Jugular Veins; | 2018 |
Lemierre's syndrome: One rare disease-Two case studies.
Topics: Adult; Anti-Bacterial Agents; beta-Lactams; Female; Fusobacterium Infections; Fusobacterium necropho | 2019 |
Intravascular abscess in Lemierre's syndrome due to meticillin-sensitive Staphylococcus aureus.
Topics: Abscess; Adult; Anti-Bacterial Agents; Cefazolin; Clindamycin; Humans; Jugular Veins; Lemierre Syndr | 2018 |
Lemierre's syndrome: the forgotten disease.
Topics: Adult; Anti-Bacterial Agents; Female; Humans; Lemierre Syndrome; Metronidazole; Penicillins | 2014 |
Importance of blood cultures to aid the diagnosis of Lemierre's syndrome.
Topics: Amoxicillin; Anti-Infective Agents; Female; Fusobacterium necrophorum; Humans; Jugular Veins; Lemier | 2015 |
Lemierre's Syndrome Associated with Periodontal Injury-derived Odontogenic Infection that Did Not Respond to Meropenem.
Topics: Adult; Anti-Bacterial Agents; Clindamycin; Dyspnea; Fever; Fusobacterium Infections; Fusobacterium n | 2015 |
Clival osteomyelitis and hypoglossal nerve palsy--rare complications of Lemierre's syndrome.
Topics: Adolescent; Anti-Infective Agents; Anticoagulants; Cranial Fossa, Posterior; Fever; Fusobacterium In | 2015 |
Angina, back pain and septic shock.
Topics: Amoxicillin; Angina, Unstable; Anti-Bacterial Agents; Back Pain; Fusobacterium necrophorum; Humans; | 2017 |
[Lemierre's syndrome as differential diagnosis of lung cancer].
Topics: Abscess; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Diagnosis, Differential; Fusobacterium | 2012 |
Lemierre syndrome.
Topics: Anti-Bacterial Agents; Ceftriaxone; Cloxacillin; Humans; Lemierre Syndrome; Male; Metronidazole; Mid | 2012 |
Doctor, I have a sore throat.
Topics: Aged, 80 and over; Anti-Bacterial Agents; Diagnosis, Differential; Humans; Jugular Veins; Lemierre S | 2013 |