metronidazole has been researched along with Lateral Sinus Thrombophlebitis in 2 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Giridharan, W | 1 |
| De, S | 1 |
| Osman, EZ | 1 |
| Amma, L | 1 |
| Hughes, J | 1 |
| McCormick, MS | 1 |
| Alonso-Ojembarrena, A | 1 |
| Amigo Bello, C | 1 |
| Martínez-Pérez, J | 1 |
| Rubio de Villanueva, JL | 1 |
2 other studies available for metronidazole and Lateral Sinus Thrombophlebitis
| Article | Year |
|---|---|
Complicated otitis media caused by Fusobacterium necrophorum.
Topics: Anti-Infective Agents; Child, Preschool; Female; Fusobacterium Infections; Fusobacterium necrophorum | 2004 |
[Sigmoid sinus thrombosis following otitis media].
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Cefotaxime; Child, Preschool; Drug Therapy, Combinatio | 2006 |