metronidazole has been researched along with Lacerations in 4 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Lacerations: Torn, ragged, mangled wounds.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tetanus is a rare diagnosis in the developed world but sporadic cases do occur." | 1.40 | Cephalic tetanus complicating geriatric fall. ( La Varis, T; Mason, D; McCabe, J, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nascimento, FA | 1 |
| Hammoud, N | 1 |
| Augusto, FD | 1 |
| Rotem, R | 1 |
| Mastrolia, SA | 1 |
| Rottenstreich, M | 1 |
| Yohay, D | 1 |
| Weintraub, AY | 1 |
| McCabe, J | 1 |
| La Varis, T | 1 |
| Mason, D | 1 |
| McLaughlin, PP | 1 |
1 review available for metronidazole and Lacerations
| Article | Year |
|---|---|
The use of metronidazole in women undergoing obstetric anal sphincter injuries: a systematic review of the literature.
Topics: Adult; Anal Canal; Anti-Bacterial Agents; Antibiotic Prophylaxis; Delivery, Obstetric; Female; Human | 2020 |
3 other studies available for metronidazole and Lacerations
| Article | Year |
|---|---|
Teaching Video NeuroImages: Cephalic tetanus: Not every facial weakness is Bell palsy.
Topics: Anti-Bacterial Agents; Bell Palsy; Debridement; Diagnosis, Differential; Facial Injuries; Facial Mus | 2019 |
Cephalic tetanus complicating geriatric fall.
Topics: Accidental Falls; Aged, 80 and over; Anti-Infective Agents; Debridement; Facial Muscles; Female; For | 2014 |
Degloving injury to mental protuberance: a case report.
Topics: Adolescent; Anti-Infective Agents; Bacterial Infections; Chin; Humans; Lacerations; Male; Mandibular | 2000 |