metronidazole has been researched along with Labor, Premature in 53 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment of bacterial vaginosis with metronidazole was effective in reducing preterm births in patients with a history of prematurity in the preceding pregnancy." | 9.07 | Effect of metronidazole in patients with preterm birth in preceding pregnancy and bacterial vaginosis: a placebo-controlled, double-blind study. ( Albritton, J; Morales, WJ; Schorr, S, 1994) |
| "A randomized, double-blind, placebo-controlled trial with 280 women between 16 and 18 weeks of pregnancy who had 1 previous preterm birth and had just been successfully treated for bacterial vaginosis with metronidazole for 1 week." | 5.14 | Effect of oral N-acetyl cysteine on recurrent preterm labor following treatment for bacterial vaginosis. ( Hassanin, IM; Hirchenhain, J; Ismail, AM; Kruessel, JS; Shahin, AY, 2009) |
| "To determine whether metronidazole reduces early preterm labour in asymptomatic women with positive vaginal fetal fibronectin (fFN) in the second trimester of pregnancy." | 5.12 | A randomised controlled trial of metronidazole for the prevention of preterm birth in women positive for cervicovaginal fetal fibronectin: the PREMET Study. ( Briley, A; Crawshaw, S; Hawken, J; Jones, G; Poston, L; Seed, P; Shennan, A, 2006) |
| " Adjunctive metronidazole therapy did not improve pregnancy outcome." | 5.10 | Periodontal disease and preterm birth: results of a pilot intervention study. ( Cliver, SP; Geurs, NC; Goldenberg, RL; Hauth, JC; Hodgkins, PM; Jeffcoat, MK; Reddy, MS, 2003) |
| "Treatment of Trichomonas vaginalis during pregnancy may be deleterious, and we infer that this may be due to metronidazole." | 5.10 | Treatment of Trichomonas in pregnancy and adverse outcomes of pregnancy: a subanalysis of a randomized trial in Rakai, Uganda. ( Brahmbhatt, H; Gray, RH; Kigozi, GG; Serwadda, D; Sewankambo, N; Wabwire-Mangen, F; Wawer, MJ, 2003) |
| "Treatment with ampicillin and metronidazole was associated with a significant prolongation of pregnancy (admission to delivery 47." | 5.08 | Ampicillin-metronidazole treatment in idiopathic preterm labour: a randomised controlled multicentre trial. ( Andersen, LF; Borch-Christensen, H; Heisterberg, L; Kristensen, J; Kryger-Baggesen, N; Langhoff-Roos, J; Svare, J, 1997) |
| "To ascertain whether metronidazole treatment of women with a heavy growth of Gardnerella vaginalis during mid-pregnancy would reduce the risk of spontaneous preterm birth." | 5.08 | Impact of metronidazole therapy on preterm birth in women with bacterial vaginosis flora (Gardnerella vaginalis): a randomised, placebo controlled trial. ( Bof, A; Harvey, JA; Jolley, PT; McDonald, HM; McDonald, PJ; O'Loughlin, JA; Vigneswaran, R, 1997) |
| "Adjuvant ampicillin and metronidazole in the management of women in preterm labour with intact membranes significantly prolonged the pregnancy and decreased neonatal morbidity." | 5.07 | Ampicillin and metronidazole treatment in preterm labour: a multicentre, randomised controlled trial. ( de Jong, P; de Souza, J; Kirsten, G; Moller, G; Norman, K; Pattinson, RC, 1994) |
| "Treatment of bacterial vaginosis with metronidazole was effective in reducing preterm births in patients with a history of prematurity in the preceding pregnancy." | 5.07 | Effect of metronidazole in patients with preterm birth in preceding pregnancy and bacterial vaginosis: a placebo-controlled, double-blind study. ( Albritton, J; Morales, WJ; Schorr, S, 1994) |
| "To evaluate whether treatment of BV with vaginal clindamycin or oral metronidazole before 28 weeks of pregnancy reduces PTL incidence." | 5.01 | Treatment of bacterial vaginosis before 28 weeks of pregnancy to reduce the incidence of preterm labor. ( Cobucci, RN; Costa, APF; Eleutério, J; Gonçalves, AK; Peixoto, RC; Rebouças, KF, 2019) |
| " Thus, the National Institute of Child Health and Human Development Maternal-Fetal Medicine Units (NICHD MFMU) Network performed a randomized clinical trial to determine if antibiotic treatment (metronidazole plus erythromycin) of asymptomatic women with a positive cervical or vaginal fetal fibronectin test in early pregnancy will reduce the risk of spontaneous preterm delivery." | 4.82 | What we have learned from an antibiotic trial in fetal fibronectin positive women. ( Andrews, WW; Goldenberg, RL, 2003) |
| "A new antibiotic combination consisting of ceftriaxone, clarithromycin, and metronidazole prolonged the latency period, reduced acute histologic chorioamnionitis/funisitis, and improved neonatal outcomes in patients with preterm PROM." | 3.83 | A new anti-microbial combination prolongs the latency period, reduces acute histologic chorioamnionitis as well as funisitis, and improves neonatal outcomes in preterm PROM. ( Chaemsaithong, P; Jun, JK; Kim, SM; Lee, J; Park, CW; Park, JS; Romero, R; Yoon, BH, 2016) |
| " Only 12% of physicians prescribed oral metronidazole or clindamycin during the first trimester of pregnancy to treat BV." | 3.72 | Bacterial vaginosis in pregnancy: diagnosis and treatment practices of physicians in San Diego, California, 1999. ( Callahan, DB; Gunn, RA; Weinberg, M, 2003) |
| "Treatment with metronidazole plus erythromycin of asymptomatic women with a positive cervical or vaginal fetal fibronectin test in the late second trimester does not decrease the incidence of spontaneous preterm delivery." | 2.71 | Randomized clinical trial of metronidazole plus erythromycin to prevent spontaneous preterm delivery in fetal fibronectin-positive women. ( Andrews, WW; Caritis, SN; Dombrowski, M; Dudley, D; Ernest, JM; Iams, JD; Langer, O; Leveno, KJ; McNellis, D; Miodovnik, M; Moawad, A; O'Sullivan, MJ; Sibai, BM; Thom, EA; Wapner, R, 2003) |
| "Eighty-nine women with either bacterial vaginosis, Trichomonas vaginalis, or both, who also had a positive fetal fibronectin test result were randomized to two courses of metronidazole treatment as part of a Maternal-Fetal Medicine Network Units study of the National Institute of Child Health and Human Development." | 2.70 | Metronidazole treatment of women with a positive fetal fibronectin test result. ( Carey, JC; Goldenberg, RL; Klebanoff, M; Macpherson, C, 2001) |
| "Sexually transmitted diseases were reduced: Trichomonas vaginalis (rate ratio, 0." | 2.70 | Randomized trial of presumptive sexually transmitted disease therapy during pregnancy in Rakai, Uganda. ( Abramowsky, C; Gray, RH; Kigozi, G; Meehan, M; Moulton, LH; O'Brien, KL; Quinn, TC; Robb, M; Serwadda, D; Sewankambo, NK; Wabwire-Mangen, F; Wawer, MJ, 2001) |
| "To assess the efficacy of treatment of bacterial vaginosis (BV) using metronidazole to reduce preterm labour in primigravidae and multigravidae with previous midtrimester abortion or preterm labour." | 2.70 | Preterm labour--is bacterial vaginosis involved? ( Grové, D; Odendaal, HJ; Popov, I; Schoeman, J; Smith, M, 2002) |
| "In clinical trials, the treatment of bacterial vaginosis in pregnant women who previously had a preterm delivery reduced the risk of recurrence." | 2.69 | Metronidazole to prevent preterm delivery in pregnant women with asymptomatic bacterial vaginosis. National Institute of Child Health and Human Development Network of Maternal-Fetal Medicine Units. ( Carey, JC; Ernest, JM; Fischer, ML; Hauth, JC; Heine, RP; Hillier, SL; Klebanoff, MA; Leveno, KJ; Nugent, RP; Thom, EA; Varner, M; Wapner, R, 2000) |
| "Of the 358 women who did not have bacterial vaginosis when initially examined, 22 percent of those assigned to metronidazole and erythromycin and 25 percent of those assigned to placebo delivered prematurely (P = 0." | 2.68 | Reduced incidence of preterm delivery with metronidazole and erythromycin in women with bacterial vaginosis. ( Andrews, WW; Copper, RL; DuBard, MB; Goldenberg, RL; Hauth, JC, 1995) |
| "Metronidazole treatment of women with trichomoniasis significantly increased the risk of preterm birth compared to placebo." | 2.42 | What have we learned about vaginal infections and preterm birth? ( Carey, JC; Klebanoff, MA, 2003) |
| "Treatment of asymptomatic bacterial vaginosis or T." | 2.41 | Bacterial vaginosis and other asymptomatic vaginal infections in pregnancy. ( Carey, JC; Klebanoff, MA, 2001) |
| "Bacterial vaginosis is associated with adverse pregnancy outcomes across all gestational ages." | 2.41 | Bacterial vaginosis in pregnancy. ( Ugwumadu, AH, 2002) |
| "Bacterial vaginosis was diagnosed by Amsel's criteria." | 1.36 | Bacterial vaginosis in threatened preterm, preterm and term labour. ( Chawanpaiboon, S; Pimol, K, 2010) |
| "Accumulating evidence has associated bacterial vaginosis (BV) with serious medical complications such as premature delivery." | 1.31 | Indications for therapy and treatment recommendations for bacterial vaginosis in nonpregnant and pregnant women: a synthesis of data. ( Hogan, V; Koumans, EH; Markowitz, LE, 2002) |
| "In the bacterial vaginosis study, intercourse between the second and third doses had a negative association with preterm birth." | 1.31 | Sexual intercourse association with asymptomatic bacterial vaginosis and Trichomonas vaginalis treatment in relationship to preterm birth. ( Berghella, V; Carey, JC; Dombrowski, MP; Ernest, JM; Hauth, JC; Heine, RP; Klebanoff, M; Langer, O; Leveno, KJ; McPherson, C; Miodovnik, M; Moawad, A; O'Sullivan, MJ; Sibai, BM; Trout, W; Van Dorsten, JP; Varner, M; Wapner, RJ, 2002) |
| "Bacterial vaginosis is associated with preterm labor." | 1.31 | The role of bacterial vaginosis in preterm labor and preterm birth: a case-control study. ( Denoit, V; Husson, MO; Le Gouëff, F; Puech, F; Subtil, D; Trivier, D, 2002) |
| "Bacterial vaginosis is associated with adverse sequelae, including late miscarriage, preterm prelabour rupture of the membranes, chorioamnionitis, postpartum endometritis and preterm labour and delivery." | 1.30 | Bacterial vaginosis: its importance in obstetrics. ( Lamont, RF; Woodrow, N, 1998) |
| "Ultrasonographic findings suggested a molar pregnancy with two live fetuses." | 1.28 | Hydatidiform mole with coexisting twin pregnancy after gamete intra-fallopian transfer. ( Hemrika, DJ; Schutte, MF; ten Velden, JJ; van de Geijn, EJ; Yedema, CA, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.89) | 18.7374 |
| 1990's | 17 (32.08) | 18.2507 |
| 2000's | 28 (52.83) | 29.6817 |
| 2010's | 6 (11.32) | 24.3611 |
| 2020's | 1 (1.89) | 2.80 |
| Authors | Studies |
|---|---|
| Jin, WH | 1 |
| Ha Kim, Y | 1 |
| Kim, JW | 1 |
| Kim, TY | 1 |
| Kim, A | 1 |
| Yang, Y | 1 |
| Thi Trung Thu, T | 1 |
| Margarita, V | 1 |
| Cocco, AR | 1 |
| Marongiu, A | 1 |
| Dessì, D | 1 |
| Rappelli, P | 1 |
| Fiori, PL | 1 |
| Yoon, BH | 2 |
| Romero, R | 2 |
| Park, JY | 1 |
| Oh, KJ | 1 |
| Lee, J | 2 |
| Conde-Agudelo, A | 1 |
| Hong, JS | 1 |
| Rebouças, KF | 1 |
| Eleutério, J | 1 |
| Peixoto, RC | 1 |
| Costa, APF | 1 |
| Cobucci, RN | 1 |
| Gonçalves, AK | 1 |
| Jensen, ML | 1 |
| Thymann, T | 1 |
| Cilieborg, MS | 1 |
| Lykke, M | 1 |
| Mølbak, L | 1 |
| Jensen, BB | 1 |
| Schmidt, M | 1 |
| Kelly, D | 1 |
| Mulder, I | 1 |
| Burrin, DG | 1 |
| Sangild, PT | 1 |
| Kim, SM | 1 |
| Chaemsaithong, P | 1 |
| Park, CW | 1 |
| Park, JS | 1 |
| Jun, JK | 1 |
| Shahin, AY | 1 |
| Hassanin, IM | 1 |
| Ismail, AM | 1 |
| Kruessel, JS | 1 |
| Hirchenhain, J | 1 |
| Chawanpaiboon, S | 1 |
| Pimol, K | 1 |
| Carey, JC | 6 |
| Klebanoff, MA | 4 |
| Koumans, EH | 1 |
| Markowitz, LE | 1 |
| Hogan, V | 1 |
| Berghella, V | 1 |
| Klebanoff, M | 2 |
| McPherson, C | 1 |
| Hauth, JC | 5 |
| Ernest, JM | 4 |
| Heine, RP | 3 |
| Wapner, RJ | 2 |
| Trout, W | 2 |
| Moawad, A | 3 |
| Leveno, KJ | 4 |
| Miodovnik, M | 3 |
| Sibai, BM | 3 |
| Van Dorsten, JP | 2 |
| Dombrowski, MP | 2 |
| O'Sullivan, MJ | 3 |
| Varner, M | 3 |
| Langer, O | 3 |
| Herbst, A | 1 |
| Wide-Swensson, D | 1 |
| Ingemarsson, I | 1 |
| Andrews, WW | 3 |
| Thom, EA | 3 |
| Dudley, D | 1 |
| McNellis, D | 2 |
| Wapner, R | 2 |
| Caritis, SN | 1 |
| Iams, JD | 1 |
| Dombrowski, M | 1 |
| Goldenberg, RL | 4 |
| Callahan, DB | 1 |
| Weinberg, M | 1 |
| Gunn, RA | 1 |
| Jeffcoat, MK | 1 |
| Geurs, NC | 1 |
| Reddy, MS | 1 |
| Cliver, SP | 1 |
| Hodgkins, PM | 1 |
| Kigozi, GG | 1 |
| Brahmbhatt, H | 1 |
| Wabwire-Mangen, F | 2 |
| Wawer, MJ | 2 |
| Serwadda, D | 2 |
| Sewankambo, N | 1 |
| Gray, RH | 2 |
| Kekki, M | 1 |
| Kurki, T | 1 |
| Kotomäki, T | 1 |
| Sintonen, H | 1 |
| Paavonen, J | 1 |
| Kazy, Z | 2 |
| Puhó, E | 2 |
| Czeizel, AE | 2 |
| Shennan, A | 1 |
| Crawshaw, S | 1 |
| Briley, A | 1 |
| Hawken, J | 1 |
| Seed, P | 1 |
| Jones, G | 1 |
| Poston, L | 1 |
| Lamont, RF | 2 |
| Dragovic, B | 1 |
| Ugwumadu, A | 1 |
| Yanamandra, N | 1 |
| Hay, P | 1 |
| McParland, PC | 1 |
| Kenyon, S | 1 |
| Bell, SC | 1 |
| Taylor, DJ | 1 |
| Darwish, A | 1 |
| Elnshar, EM | 1 |
| Hamadeh, SM | 1 |
| Makarem, MH | 1 |
| DuBard, MB | 1 |
| Copper, RL | 1 |
| McCoy, MC | 1 |
| Katz, VL | 1 |
| Kuller, JA | 1 |
| Killam, AP | 1 |
| Livengood, CH | 1 |
| Collins, T | 1 |
| Bancroft, K | 1 |
| Manyonda, I | 1 |
| Khan, Z | 1 |
| Norman, K | 1 |
| Pattinson, RC | 1 |
| de Souza, J | 1 |
| de Jong, P | 1 |
| Moller, G | 1 |
| Kirsten, G | 1 |
| Morales, WJ | 1 |
| Schorr, S | 1 |
| Albritton, J | 1 |
| Oyarzún, E | 1 |
| Gómez, R | 1 |
| Montiel, F | 1 |
| Steele, RW | 1 |
| Svare, J | 1 |
| Langhoff-Roos, J | 1 |
| Andersen, LF | 1 |
| Kryger-Baggesen, N | 1 |
| Borch-Christensen, H | 1 |
| Heisterberg, L | 1 |
| Kristensen, J | 1 |
| McDonald, HM | 1 |
| O'Loughlin, JA | 1 |
| Vigneswaran, R | 1 |
| Jolley, PT | 1 |
| Harvey, JA | 1 |
| Bof, A | 1 |
| McDonald, PJ | 1 |
| Gardó, S | 1 |
| Woodrow, N | 1 |
| McClean, H | 1 |
| Faro, S | 1 |
| Sørensen, HT | 1 |
| Larsen, H | 1 |
| Jensen, ES | 1 |
| Thulstrup, AM | 1 |
| Schønheyder, HC | 1 |
| Nielsen, GL | 1 |
| Czeizel, A | 1 |
| Hillier, SL | 2 |
| Nugent, RP | 2 |
| Fischer, ML | 1 |
| Bowden, FJ | 1 |
| Garnett, GP | 1 |
| Lazar, PA | 1 |
| Donders, GG | 1 |
| Riphagen, I | 1 |
| van den Bosch, T | 1 |
| Macpherson, C | 1 |
| Roberts, JM | 1 |
| Kigozi, G | 1 |
| Sewankambo, NK | 1 |
| Moulton, LH | 1 |
| Quinn, TC | 1 |
| O'Brien, KL | 1 |
| Meehan, M | 1 |
| Abramowsky, C | 1 |
| Robb, M | 1 |
| Subtil, D | 1 |
| Denoit, V | 1 |
| Le Gouëff, F | 1 |
| Husson, MO | 1 |
| Trivier, D | 1 |
| Puech, F | 1 |
| Ugwumadu, AH | 1 |
| Odendaal, HJ | 1 |
| Popov, I | 1 |
| Schoeman, J | 1 |
| Smith, M | 1 |
| Grové, D | 1 |
| van de Geijn, EJ | 1 |
| Yedema, CA | 1 |
| Hemrika, DJ | 1 |
| Schutte, MF | 1 |
| ten Velden, JJ | 1 |
| Swedberg, JA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Oral N-Acetyl Cysteine on Pregnancy Outcome After Cervical Cerclage: a Randomized Controlled Trial[NCT00787813] | 100 participants (Anticipated) | Interventional | 2008-06-30 | Completed | |||
| Phase III Trial of Antibiotics to Reduce Chorioamnionitis-Related Perinatal HIV Transmission[NCT00021671] | Phase 3 | 3,720 participants | Interventional | Completed | |||
| Clindamycin to Reduce Preterm Birth in a Low Resource Setting: A Randomized Placebo-controlled Trial[NCT01800825] | Phase 4 | 1,726 participants (Actual) | Interventional | 2013-07-31 | Completed | ||
| Pregnancy Outcomes Following Preconception Treatment of Asymptomatic Bacterial Vaginosis in an Infertility Population: A Prospective, Randomized, Double-Blind, Placebo-Controlled Trial.[NCT01322971] | 2 participants (Actual) | Interventional | 2011-02-28 | Terminated (stopped due to Disease prevalence lower than expected in population.) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
10 reviews available for metronidazole and Labor, Premature
| Article | Year |
|---|---|
Treatment of bacterial vaginosis before 28 weeks of pregnancy to reduce the incidence of preterm labor.
Topics: Administration, Intravaginal; Administration, Oral; Anti-Bacterial Agents; Clindamycin; Female; Huma | 2019 |
Bacterial vaginosis and other asymptomatic vaginal infections in pregnancy.
Topics: Adult; Anti-Bacterial Agents; Chlamydia Infections; Comorbidity; Female; Gonorrhea; Humans; Incidenc | 2001 |
What have we learned about vaginal infections and preterm birth?
Topics: Anti-Infective Agents; Antitrichomonal Agents; Female; Humans; Metronidazole; National Institutes of | 2003 |
What we have learned from an antibiotic trial in fetal fibronectin positive women.
Topics: Anti-Infective Agents; Drug Therapy, Combination; Erythromycin; Female; Fibronectins; Humans; Metron | 2003 |
Bacterial vaginosis in pregnancy: an approach for the 1990s.
Topics: Clindamycin; Female; Fetal Membranes, Premature Rupture; Gestational Age; Humans; Metronidazole; Obs | 1995 |
[Bacterial vaginosis II. Related pathology and therapy].
Topics: Anti-Bacterial Agents; Chorioamnionitis; Clindamycin; Endometritis; Female; Humans; Metronidazole; O | 1995 |
Reduced incidence of preterm delivery with metronidazole and erythromycin in women with bacterial vaginosis.
Topics: Drug Therapy, Combination; Erythromycin; Female; Humans; Metronidazole; Obstetric Labor, Premature; | 1996 |
[Bacterial vaginosis].
Topics: Anti-Bacterial Agents; Antitrichomonal Agents; Clindamycin; Female; Humans; Metronidazole; Obstetric | 1998 |
Bacterial vaginosis in pregnancy.
Topics: Abortion, Spontaneous; Chorionic Gonadotropin; Cytokines; Female; Humans; Metronidazole; Obstetric L | 2002 |
Bacterial vaginosis: etiology, association with preterm labor, diagnosis, and management.
Topics: Female; Humans; Metronidazole; Obstetric Labor, Premature; Pregnancy; Pregnancy Complications, Infec | 1989 |
16 trials available for metronidazole and Labor, Premature
| Article | Year |
|---|---|
Effect of oral N-acetyl cysteine on recurrent preterm labor following treatment for bacterial vaginosis.
Topics: Acetylcysteine; Administration, Oral; Adult; Anti-Infective Agents; Drug Therapy, Combination; Femal | 2009 |
Randomized clinical trial of metronidazole plus erythromycin to prevent spontaneous preterm delivery in fetal fibronectin-positive women.
Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Drug Therapy, Combination; Enzyme-Linked Immuno | 2003 |
Periodontal disease and preterm birth: results of a pilot intervention study.
Topics: Adult; Anti-Infective Agents; Dental Scaling; Double-Blind Method; Feasibility Studies; Female; Huma | 2003 |
Treatment of Trichomonas in pregnancy and adverse outcomes of pregnancy: a subanalysis of a randomized trial in Rakai, Uganda.
Topics: Animals; Antitrichomonal Agents; Birth Rate; Drug Therapy, Combination; Female; Humans; Infant Morta | 2003 |
A randomised controlled trial of metronidazole for the prevention of preterm birth in women positive for cervicovaginal fetal fibronectin: the PREMET Study.
Topics: Administration, Oral; Adult; Anti-Infective Agents; Biomarkers; Birth Weight; Cervix Uteri; Double-B | 2006 |
Treatment options for bacterial vaginosis in patients at high risk of preterm labor and premature rupture of membranes.
Topics: Administration, Intravaginal; Administration, Oral; Adult; Anti-Bacterial Agents; Clindamycin; Femal | 2007 |
Reduced incidence of preterm delivery with metronidazole and erythromycin in women with bacterial vaginosis.
Topics: Adult; Anti-Bacterial Agents; Antitrichomonal Agents; Body Weight; Double-Blind Method; Erythromycin | 1995 |
Reduced incidence of preterm delivery with metronidazole and erythromycin in women with bacterial vaginosis.
Topics: Adult; Anti-Bacterial Agents; Antitrichomonal Agents; Body Weight; Double-Blind Method; Erythromycin | 1995 |
Reduced incidence of preterm delivery with metronidazole and erythromycin in women with bacterial vaginosis.
Topics: Adult; Anti-Bacterial Agents; Antitrichomonal Agents; Body Weight; Double-Blind Method; Erythromycin | 1995 |
Reduced incidence of preterm delivery with metronidazole and erythromycin in women with bacterial vaginosis.
Topics: Adult; Anti-Bacterial Agents; Antitrichomonal Agents; Body Weight; Double-Blind Method; Erythromycin | 1995 |
Ampicillin and metronidazole treatment in preterm labour: a multicentre, randomised controlled trial.
Topics: Adult; Ampicillin; Birth Weight; Drug Therapy, Combination; Female; Gestational Age; Humans; Metroni | 1994 |
Effect of metronidazole in patients with preterm birth in preceding pregnancy and bacterial vaginosis: a placebo-controlled, double-blind study.
Topics: Adult; Double-Blind Method; Female; Fetal Membranes, Premature Rupture; Humans; Infant, Newborn; Inf | 1994 |
Ampicillin-metronidazole treatment in idiopathic preterm labour: a randomised controlled multicentre trial.
Topics: Administration, Oral; Adult; Ampicillin; Double-Blind Method; Drug Therapy, Combination; Female; Ges | 1997 |
Impact of metronidazole therapy on preterm birth in women with bacterial vaginosis flora (Gardnerella vaginalis): a randomised, placebo controlled trial.
Topics: Adult; Antitrichomonal Agents; Female; Gardnerella vaginalis; Humans; Metronidazole; Obstetric Labor | 1997 |
Metronidazole to prevent preterm delivery in pregnant women with asymptomatic bacterial vaginosis. National Institute of Child Health and Human Development Network of Maternal-Fetal Medicine Units.
Topics: Adult; Anti-Infective Agents; Disease-Free Survival; Double-Blind Method; Female; Humans; Infant, Ne | 2000 |
Metronidazole treatment of women with a positive fetal fibronectin test result.
Topics: Anti-Infective Agents; Cervix Uteri; Female; Fibronectins; Gestational Age; Glycoproteins; Humans; M | 2001 |
Failure of metronidazole to prevent preterm delivery among pregnant women with asymptomatic Trichomonas vaginalis infection.
Topics: Adult; Animals; Antitrichomonal Agents; Female; Follow-Up Studies; Humans; Infant, Newborn; Infant, | 2001 |
Randomized trial of presumptive sexually transmitted disease therapy during pregnancy in Rakai, Uganda.
Topics: Azithromycin; Birth Weight; Cefixime; Drug Therapy, Combination; Endophthalmitis; Female; Folic Acid | 2001 |
Preterm labour--is bacterial vaginosis involved?
Topics: Adult; Anti-Infective Agents; Female; Gestational Age; Gravidity; Humans; Metronidazole; Obstetric L | 2002 |
27 other studies available for metronidazole and Labor, Premature
| Article | Year |
|---|---|
Antibiotic treatment of amniotic fluid "sludge" in patients during the second or third trimester with uterine contraction.
Topics: Adult; Amniotic Fluid; Anti-Bacterial Agents; Ceftriaxone; Clarithromycin; Cohort Studies; Female; H | 2021 |
Topics: Amniotic Fluid; Anti-Bacterial Agents; Extraembryonic Membranes; Female; Humans; Metronidazole; Myco | 2018 |
Antibiotic administration can eradicate intra-amniotic infection or intra-amniotic inflammation in a subset of patients with preterm labor and intact membranes.
Topics: Adult; Amniocentesis; Amniotic Fluid; Anti-Bacterial Agents; Biomarkers; Ceftriaxone; Chorioamnionit | 2019 |
Antibiotics modulate intestinal immunity and prevent necrotizing enterocolitis in preterm neonatal piglets.
Topics: Amino Acids; Ampicillin; Animals; Animals, Newborn; Anti-Bacterial Agents; Antibiotic Prophylaxis; D | 2014 |
A new anti-microbial combination prolongs the latency period, reduces acute histologic chorioamnionitis as well as funisitis, and improves neonatal outcomes in preterm PROM.
Topics: Adult; Anti-Bacterial Agents; Ceftriaxone; Chorioamnionitis; Clarithromycin; Drug Therapy, Combinati | 2016 |
Bacterial vaginosis in threatened preterm, preterm and term labour.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Female; Gestational Age; Humans; Infant, Newborn; Infant, | 2010 |
Indications for therapy and treatment recommendations for bacterial vaginosis in nonpregnant and pregnant women: a synthesis of data.
Topics: Anti-Infective Agents; Clindamycin; Drug Therapy; Female; Humans; Metronidazole; Obstetric Labor, Pr | 2002 |
Sexual intercourse association with asymptomatic bacterial vaginosis and Trichomonas vaginalis treatment in relationship to preterm birth.
Topics: Animals; Anti-Infective Agents; Black or African American; Coitus; Double-Blind Method; Female; Huma | 2002 |
Significant delay of birth in advanced preterm labour at 23 gestational weeks with an oxytocin antagonist.
Topics: Adult; Anti-Bacterial Agents; C-Reactive Protein; Cefuroxime; Cervix Uteri; Female; Gestational Age; | 2003 |
Bacterial vaginosis in pregnancy: diagnosis and treatment practices of physicians in San Diego, California, 1999.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; California; Clindamycin; Cross-Sectional Studies; Fema | 2003 |
Cost-effectiveness of screening and treatment for bacterial vaginosis in early pregnancy among women at low risk for preterm birth.
Topics: Anti-Infective Agents; Clindamycin; Cost-Benefit Analysis; Decision Trees; Diagnosis-Related Groups; | 2004 |
Gestational age and prevalence of preterm birth after vaginal metronidazole treatment during pregnancy.
Topics: Administration, Intravaginal; Anti-Infective Agents; Birth Weight; Case-Control Studies; Female; Ges | 2004 |
Effect of vaginal metronidazole + miconazole treatment during pregnancy for gestational age and birth weight in a population-based study.
Topics: Administration, Intravaginal; Adult; Antifungal Agents; Birth Weight; Case-Control Studies; Female; | 2005 |
A randomised controlled trial of metronidazole for the prevention of preterm birth in women positive for cervicovaginal fetal fibronectin: the PREMET Study by Shennan et al.
Topics: Anti-Infective Agents; Biomarkers; Female; Fibronectins; Glycoproteins; Humans; Metronidazole; Obste | 2006 |
A randomised controlled trial of metronidazole for the prevention of preterm birth in women positive for cervicovaginal fetal fibronectin: the PREMET study.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Biomarkers; Clindamycin; Female; Fibronectins; Glycopr | 2006 |
A randomised controlled trial of metronidazole for the prevention of preterm birth in women positive for cervicovaginal fetal fibronectin: the PREMET Study.
Topics: Anti-Infective Agents; Biomarkers; Female; Fibronectins; Humans; Metronidazole; Obstetric Labor, Pre | 2006 |
Ampicillin and metronidazole treatment in preterm labour: a multicentre, randomised trial.
Topics: Ampicillin; Female; Humans; Metronidazole; Multicenter Studies as Topic; Obstetric Labor, Premature; | 1995 |
Active management of preterm labour and preterm prelabour rupture of membranes.
Topics: Analgesics; Anti-Bacterial Agents; Embryonic and Fetal Development; Female; Fetal Membranes, Prematu | 1994 |
Bacterial vaginosis: its importance in obstetrics.
Topics: Abortion, Spontaneous; Anti-Infective Agents; Chorioamnionitis; Endometritis; Female; Humans; Metron | 1998 |
Impact of metronidazole therapy on preterm birth in women with bacterial vaginosis flora.
Topics: Anti-Infective Agents; Data Interpretation, Statistical; Female; Humans; Metronidazole; Obstetric La | 1998 |
Screening for bacterial vaginosis.
Topics: Anti-Infective Agents; Female; Humans; Mass Screening; Metronidazole; Obstetric Labor, Premature; Pr | 1998 |
Safety of metronidazole during pregnancy: a cohort study of risk of congenital abnormalities, preterm delivery and low birth weight in 124 women.
Topics: Abnormalities, Drug-Induced; Adult; Anti-Infective Agents; Cohort Studies; Female; Humans; Infant, L | 1999 |
Why is Trichomonas vaginalis ignored?
Topics: Animals; Antitrichomonal Agents; Ethnicity; Female; Humans; Incidence; Male; Metronidazole; Obstetri | 1999 |
Does oral metronidazole prevent preterm delivery in normal-risk pregnant women with asymptomatic bacterial vaginosis (BV)?
Topics: Anti-Infective Agents; Delivery, Obstetric; Double-Blind Method; Female; Gestational Age; Humans; In | 2000 |
Abnormal vaginal flora, cervical length and preterm birth.
Topics: Cervical Ripening; Female; Gestational Age; Humans; Metronidazole; Obstetric Labor, Premature; Predi | 2000 |
The role of bacterial vaginosis in preterm labor and preterm birth: a case-control study.
Topics: Adult; Anti-Infective Agents; Case-Control Studies; Female; Fetal Membranes, Premature Rupture; Gest | 2002 |
Hydatidiform mole with coexisting twin pregnancy after gamete intra-fallopian transfer.
Topics: Adult; Amoxicillin; Female; Gamete Intrafallopian Transfer; Humans; Hydatidiform Mole; Male; Metroni | 1992 |