Page last updated: 2024-10-31

metronidazole and Kidney Neoplasms

metronidazole has been researched along with Kidney Neoplasms in 3 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Kidney Neoplasms: Tumors or cancers of the KIDNEY.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Velez, MC1
Athale, UH1
Loe, W1
Warrier, RP1
Garavelli, PL1
Stewart, DJ1
Futter, N1
Irvine, A1
Danjoux, C1
Moors, D1

Other Studies

3 other studies available for metronidazole and Kidney Neoplasms

ArticleYear
Acute perforative appendicitis during preoperative chemotherapy for Wilms tumor.
    Pediatric hematology and oncology, 2003, Volume: 20, Issue:2

    Topics: Abdominal Pain; Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Appendicitis; Ceftazi

2003
The therapy of blastocystosis.
    Journal of chemotherapy (Florence, Italy), 1991, Volume: 3 Suppl 1

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Aged; Aged, 80 and over; Animals; Anti-Infect

1991
Mitomycin-C and metronidazole in the treatment of advanced renal-cell carcinoma.
    American journal of clinical oncology, 1987, Volume: 10, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Female; Humans;

1987