metronidazole has been researched along with Jaundice in 6 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Jaundice: A clinical manifestation of HYPERBILIRUBINEMIA, characterized by the yellowish staining of the SKIN; MUCOUS MEMBRANE; and SCLERA. Clinical jaundice usually is a sign of LIVER dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Group A comprised of patients clinically diagnosed to have amoebic liver abscess and received Metronidazole 500mg iv x 8 hourly for atleast 10 days or more if patient developed complications." | 3.71 | Amoebic versus pyogenic liver abscess. ( Ahmed, N; Ahsan, T; Anwer, A; Jehangir, MU; Mahmood, T; Saleem, M; Shaheer, A; Shahid, M, 2002) |
| "Metronidazole is an effective treatment and none of the patients required an invasive method for diagnosis or treatment." | 1.31 | Clinical characteristic of amoebic liver abscesses in the North of Iraq. ( Baban, FA, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Hunaut, T | 1 |
| Boulagnon-Rombi, C | 1 |
| Thorn, H | 1 |
| Doco-Fenzy, M | 1 |
| Thiéfin, G | 1 |
| Michalski, T | 1 |
| Nakanishi, Y | 1 |
| Seno, H | 1 |
| Chiba, T | 1 |
| Yamashita, Y | 1 |
| Ahsan, T | 1 |
| Jehangir, MU | 1 |
| Mahmood, T | 1 |
| Ahmed, N | 1 |
| Saleem, M | 1 |
| Shahid, M | 1 |
| Shaheer, A | 1 |
| Anwer, A | 1 |
| Ha, GY | 1 |
| Yang, CH | 1 |
| Kim, H | 1 |
| Chong, Y | 1 |
| Baban, FA | 1 |
1 review available for metronidazole and Jaundice
| Article | Year |
|---|---|
Hepatotoxicity of metronidazole in Cockayne syndrome: A clinical report.
Topics: Adult; Anti-Infective Agents; Chemical and Drug Induced Liver Injury; Cockayne Syndrome; Humans; Jau | 2022 |
5 other studies available for metronidazole and Jaundice
| Article | Year |
|---|---|
[70 year old female patient with unclear skin color].
Topics: Abdominal Pain; Aged; Cholestasis; Diagnosis, Differential; Diverticulitis, Colonic; Face; Female; H | 2009 |
Education and imaging. Hepatobiliary and pancreatic: multiple sexually transmitted infections.
Topics: Acute Disease; Anti-Infective Agents; Antiprotozoal Agents; Antiviral Agents; Colonoscopy; Entamoebi | 2010 |
Amoebic versus pyogenic liver abscess.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Antiprotozoal Agents; Cefotaxime; Cohort Studies; Di | 2002 |
Case of sepsis caused by Bifidobacterium longum.
Topics: Actinomycetales Infections; Acupuncture Analgesia; Adult; Anti-Bacterial Agents; Bifidobacterium; Fe | 1999 |
Clinical characteristic of amoebic liver abscesses in the North of Iraq.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Diagnosis, Differential; Fever; Hepatomegaly; Humans | 2000 |