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metronidazole and Intestinal Polyps

metronidazole has been researched along with Intestinal Polyps in 4 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Intestinal Polyps: Discrete abnormal tissue masses that protrude into the lumen of the INTESTINE. A polyp is attached to the intestinal wall either by a stalk, pedunculus, or by a broad base.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ugajin, T1
Miyatani, H1
Matsumoto, S1
Takamatsu, T1
Fukunishi, M1
Yoshida, Y1
Dobashi, Y1
Taylor, EW1
Bentley, S1
Youngs, D1
Keighley, MR1
Yousfi, MM1
el-Zimaity, HM1
Cole, RA1
Genta, RM1
Graham, DY1
Werner, GT1

Other Studies

4 other studies available for metronidazole and Intestinal Polyps

ArticleYear
Regression of multiple duodenal hyperplastic polyps following Helicobacter pylori eradication.
    Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 2011, Volume: 23, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Biop

2011
Bowel preparation and the safety of colonoscopic polypectomy.
    Gastroenterology, 1981, Volume: 81, Issue:1

    Topics: Administration, Oral; Colon; Colonoscopy; Explosions; Gases; Humans; Intestinal Polyps; Mannitol; Me

1981
Resolution of a metaplastic duodenal polyp after cure of Helicobacter pylori infection.
    Journal of clinical gastroenterology, 1996, Volume: 23, Issue:1

    Topics: Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Duodenal Neoplasms; Helicobacter Infection

1996
[Diagnosis of amebiasis].
    Medizinische Klinik, 1979, Sep-21, Volume: 74, Issue:38

    Topics: Adult; Amebiasis; Crohn Disease; Diagnosis, Differential; Drug Therapy, Combination; Emetine; Humans

1979