metronidazole has been researched along with Intestinal Polyps in 4 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Intestinal Polyps: Discrete abnormal tissue masses that protrude into the lumen of the INTESTINE. A polyp is attached to the intestinal wall either by a stalk, pedunculus, or by a broad base.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (50.00) | 18.7374 |
1990's | 1 (25.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (25.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Ugajin, T | 1 |
Miyatani, H | 1 |
Matsumoto, S | 1 |
Takamatsu, T | 1 |
Fukunishi, M | 1 |
Yoshida, Y | 1 |
Dobashi, Y | 1 |
Taylor, EW | 1 |
Bentley, S | 1 |
Youngs, D | 1 |
Keighley, MR | 1 |
Yousfi, MM | 1 |
el-Zimaity, HM | 1 |
Cole, RA | 1 |
Genta, RM | 1 |
Graham, DY | 1 |
Werner, GT | 1 |
4 other studies available for metronidazole and Intestinal Polyps
Article | Year |
---|---|
Regression of multiple duodenal hyperplastic polyps following Helicobacter pylori eradication.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Biop | 2011 |
Bowel preparation and the safety of colonoscopic polypectomy.
Topics: Administration, Oral; Colon; Colonoscopy; Explosions; Gases; Humans; Intestinal Polyps; Mannitol; Me | 1981 |
Resolution of a metaplastic duodenal polyp after cure of Helicobacter pylori infection.
Topics: Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Duodenal Neoplasms; Helicobacter Infection | 1996 |
[Diagnosis of amebiasis].
Topics: Adult; Amebiasis; Crohn Disease; Diagnosis, Differential; Drug Therapy, Combination; Emetine; Humans | 1979 |