Page last updated: 2024-10-31

metronidazole and Intestinal Perforation

metronidazole has been researched along with Intestinal Perforation in 54 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Intestinal Perforation: Opening or penetration through the wall of the INTESTINES.

Research Excerpts

ExcerptRelevanceReference
"To demonstrate the efficacy of oral metronidazole (OM) in simple or complicated appendicitis with localized peritonitis, a randomized prospective study was carried out in 1083 patients, ranging in age from 4 to 50 years (mean age, 21."9.09Can oral metronidazole substitute parenteral drug therapy in acute appendicitis? A new policy in the management of simple or complicated appendicitis with localized peritonitis: a randomized controlled clinical trial. ( Banani, SA; Talei, A, 1999)
"To demonstrate the efficacy of oral metronidazole (OM) in simple or complicated appendicitis with localized peritonitis, a randomized prospective study was carried out in 1083 patients, ranging in age from 4 to 50 years (mean age, 21."5.09Can oral metronidazole substitute parenteral drug therapy in acute appendicitis? A new policy in the management of simple or complicated appendicitis with localized peritonitis: a randomized controlled clinical trial. ( Banani, SA; Talei, A, 1999)
" Patients with free purulent peritonitis due to perforated appendicitis or colonic perforation were treated with intravenous infusion of cefuroxime and metronidazole."5.06A prospective randomized study of continuous peritoneal lavage postoperatively in the treatment of purulent peritonitis. ( Andersson, C; Englund, N; Glise, H; Hallerbäck, B; Nihlberg, A; Solhaug, J; Wahlström, B, 1986)
" difficile diarrhea with metronidazole or vancomycin is highly effective at relieving symptoms."4.80Treatment of Clostridium difficile-associated diarrhea and colitis. ( Gerding, DN, 2000)
"None of these patients had a fever or leukocytosis at discharge."2.70Oral antibiotics in the management of perforated appendicitis in children. ( Abarbanell, A; Gollin, G; Moores, D, 2002)
"Surgical wound infections were significantly reduced by the collagen-gentamicin implant."2.69Effectiveness of collagen-gentamicin implant for treatment of "dirty" abdominal wounds. ( Delgado, FJ; Guerrero, TS; Guzmán Valdivia Gomez, G; Lluck, MC, 1999)
"Cefepime is a new extended-spectrum cephalosporin with gram-positive and gram-negative coverage including Staphylococcus aureus and Pseudomonas aeruginosa."2.67Analysis of cefepime tissue penetration into human appendix. ( Appleman, MD; Berne, TV; Chin, A; Gill, MA; Heseltine, PN; Knupp, CA; Okamoto, MP; Sclar, DA; Yellin, AE, 1991)
"Although amebiasis is usually asymptomatic, fulminant amebic colitis is associated with a high mortality rate."1.62[A case of amebic colitis that developed after corticosteroid therapy in which perforation occurred during metronidazole treatment]. ( Higashino, M; Iwata, F; Kato, A; Miyagaki, A; Motomura, Y; Okamoto, R; Saito, A; Yamaguchi, E, 2021)
"Various complications are reported with Clostridium difficile infection (CDI), including fulminant CDI."1.46Cecal Perforation Associated with Clostridium difficile Infection: A Case Report. ( Luthe, SK; Sato, R, 2017)
"Nonoperative treatment of acute diverticulitis with extraluminal air is safe and effective in patients with a small amount of distant intraperitoneal air or pericolic air without clinical signs of peritonitis."1.40Nonoperative management of perforated diverticulitis with extraluminal air is safe and effective in selected patients. ( Leppäniemi, AK; Mentula, PJ; Sallinen, VJ, 2014)
"Fulminant amoebic colitis is very rarely associated with chemotherapy."1.35Fulminant amoebic colitis during chemotherapy for advanced gastric cancer. ( Ae, T; Hanaoka, N; Higuchi, K; Ishido, K; Koizumi, W; Saigenji, K; Sasaki, T; Tanabe, S, 2009)
"Typhoid intestinal perforation is a common complication of typhoid fever in our environment."1.35Typhoid intestinal disease: 32 perforations in 1 patient. ( Abdur-Rahman, LO; Adeniran, JO; Nasir, AA; Odi, TO; Omotayo, JA, 2008)
"metronidazole (MTR) was compared with i."1.32Results of a prospective, randomized, double blind comparison of the efficacy and the safety of sequential ciprofloxacin (intravenous/oral)+metronidazole (intravenous/oral) with ceftriaxone (intravenous)+metronidazole (intravenous/oral) for the treatment ( Asimakopoulos, C; Bassaris, H; Harlaftis, N; Karravias, D; Kolaras, P; Nikolaidis, P; Skoutelis, A; Starakis, I, 2003)
"The postoperative complications were suppuration of the wall (n = 4), intestinal fistula (n = 3), evisceration, and residual abscess."1.29[Typhoid perforations: experiences in a surgical setting in Cameroon. Apropos of 49 cases]. ( Ibile, A; Malonga, E; Masso-Misse, P; Yao, JG, 1994)
"Forty cases of typhoid ileal perforation were treated surgically in three years."1.29Typhoid perforation treated with and without metronidazole along with chloramphenicol, gentamycin. ( Ahmad, G; Dab, RH; Javaid, K; Rathore, AH, 1996)
"Fulminant transmural amoebic colitis is a rare life-threatening complication of invasive bowel amebiasis."1.29[Post-partum malignant amebic colitis. Apropos of a case]. ( Andreu, JM; Bourdeix, O; Brissiaud, JC; Diallo, B; Michel, G; Sartelet, H; Vicq, P, 1996)

Research

Studies (54)

TimeframeStudies, this research(%)All Research%
pre-199019 (35.19)18.7374
1990's12 (22.22)18.2507
2000's14 (25.93)29.6817
2010's8 (14.81)24.3611
2020's1 (1.85)2.80

Authors

AuthorsStudies
Kato, A1
Iwata, F1
Higashino, M1
Miyagaki, A1
Yamaguchi, E1
Okamoto, R1
Saito, A1
Motomura, Y1
Hélias, M1
Planchon, J1
Bousquet, A1
Dubost, C1
Kaufman, E1
Liska, D1
Rubinshteyn, V1
Nandakumar, G1
Xiao, YF1
Bai, JY1
Yu, J1
Lin, XL1
Zhao, XY1
Yang, SM1
Fan, CQ1
Sallinen, VJ1
Mentula, PJ1
Leppäniemi, AK1
Torrijo Gómez, I1
Uribe Quintana, N1
Catalá Llosa, J1
Raga Vázquez, J1
Sellés Dechent, R1
Martín Dieguez, MC1
Báguena Requena, G1
Asencio Arana, F1
Liu, J1
Fan, P1
Chu, J1
Yang, J1
Yang, X1
Zhang, L1
Guo, C1
Luthe, SK1
Sato, R1
Kiyak, G1
Ergul, E1
Celik, A1
Weiss, G1
Reimnitz, P1
Hampel, B1
Muehlhofer, E1
Lippert, H1
Hanaoka, N1
Higuchi, K1
Tanabe, S1
Sasaki, T1
Ishido, K1
Ae, T1
Koizumi, W1
Saigenji, K1
Rebai, W1
Makni, A1
Azouz, H1
Ksantini, R1
Kourda, J1
Chebbi, F1
Daghfous, A1
Ayadi, S1
Ftériche, F1
Bedioui, H1
Jouini, M1
Kacem, M1
Ammous, A1
Ben Safta, Z1
Starakis, I1
Karravias, D1
Asimakopoulos, C1
Kolaras, P1
Nikolaidis, P2
Harlaftis, N1
Skoutelis, A1
Bassaris, H1
Gollin, G2
Abarbanell, A1
Moores, D1
Tomás, ME1
Pérez Carreras, M1
Morillasa, JD1
Castellano, G1
Solís, JA1
Velez, MC1
Athale, UH1
Loe, W1
Warrier, RP1
Turnbull, IR1
Wlzorek, JJ1
Osborne, D1
Hotchkiss, RS1
Coopersmith, CM1
Buchman, TG1
Chiang, TH1
Liu, KL1
Lee, YC1
Chiu, HM1
Lin, JT1
Wang, HP1
Nasir, AA1
Adeniran, JO1
Abdur-Rahman, LO1
Odi, TO1
Omotayo, JA1
Singleton, JW1
Schultz, A1
Jørgensen, PM1
Jørgensen, SP1
Brennan, SS1
Smith, GM1
Evans, M1
Pollock, AV1
Pinto, DJ1
Sanderson, PJ1
Stewart, D1
Yao, JG1
Masso-Misse, P1
Ibile, A1
Malonga, E1
Schmitt, M1
Bondonny, JM1
Delmas, P1
Galifer, RB1
Revillon, Y1
Robert, M1
O'Sullivan, GC1
Murphy, D1
O'Brien, MG1
Ireland, A1
Javaid, K1
Dab, RH1
Rathore, AH1
Ahmad, G1
Bourdeix, O1
Andreu, JM1
Sartelet, H1
Diallo, B1
Brissiaud, JC1
Vicq, P1
Michel, G1
Moesgaard, F1
Jensen, LS1
Christiansen, PM1
Thorlacius-Ussing, O1
Nielsen, KT1
Rasmussen, NR1
Bardram, L1
Nielsen, HJ1
Guzmán Valdivia Gomez, G1
Guerrero, TS1
Lluck, MC1
Delgado, FJ1
Banani, SA1
Talei, A1
Ohlin, B1
Cederberg, A1
Forssell, H1
Solhaug, JH1
Tveit, E1
Gerding, DN1
Besselink, MG1
Berende, NC1
Preshaw, RM1
Romano, C1
Kortbeek, J1
Maltezou, HC1
Lebesii, E1
Dimitriou, L1
Androulakakis, E1
Kafetzis, DA1
Rice, HE1
Brown, RL1
Caty, MG1
Gilbert, J1
Skinner, MA1
Glick, PL1
Azizkhan, RG1
Rotimi, VO1
Duerden, BI1
Ede, V1
MacKinnon, AE1
Adams, EB1
MacLeod, IN1
Okamoto, MP1
Chin, A1
Gill, MA1
Yellin, AE1
Berne, TV1
Heseltine, PN1
Appleman, MD1
Knupp, CA1
Sclar, DA1
Birkigt, HG1
Beyer, H1
Thomas, SS1
Mammen, KJ1
Eggleston, FC1
de Louvois, J1
Allard, JC1
Kuligowska, E1
Barth, A1
Kuhn, P1
Bertschmann, W1
Brousil, L1
Höllwarth, M1
Graf, D1
Kurz, R1
Sauer, H1
Hallerbäck, B1
Andersson, C1
Englund, N1
Glise, H1
Nihlberg, A1
Solhaug, J1
Wahlström, B1
Go, PM1
Luyendijk, R1
Munting, JD1
Ribbans, WJ1
Radcliffe, AG1
Clemens, M1
Dobrai, I1
Szentes, G1
Szatmári, S1
Farkas, J1
Balikian, JP1
Uthman, SM1
Khouri, NF1
Archampong, EQ1
Clark, CG1
Prakash, A1
Sharma, LK1
Prandit, PN1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prophylaxis With Single Versus Five Dose of Antibiotic Therapy as Treatment of Patients With Gangrenous Acute Appendicitis (Randomized, Controlled Clinical Trial)[NCT01115153]150 participants (Actual)Interventional2007-12-31Completed
PROTOP: Study of the Efficacy of Topical Antibiotherapy in the Prophylaxis of Incisional Surgical Localization Infection in Colorectal Surgery[NCT03574090]Phase 4268 participants (Actual)Interventional2020-10-20Completed
Laparoscopic Lavage for Acute Non-Faeculant Diverticulitis[NCT01019239]300 participants (Anticipated)Interventional2010-01-31Enrolling by invitation
Management and Evolution of Acute Diverticulitis With Pericolic Free Gas - a Multicentre Observational Study[NCT04311385]1,000 participants (Actual)Observational2020-06-01Completed
Collagen-Gentamicin Implant in the Treatment of Contaminated Surgical Abdominal Wounds - A Randomized Controlled Trial[NCT00977405]Phase 270 participants (Anticipated)Interventional2009-09-30Terminated
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for metronidazole and Intestinal Perforation

ArticleYear
Treatment of Clostridium difficile-associated diarrhea and colitis.
    Current topics in microbiology and immunology, 2000, Volume: 250

    Topics: Abdomen, Acute; Anti-Bacterial Agents; Antidiarrheals; Clinical Trials as Topic; Clostridioides diff

2000
Necrotising enterocolitis.
    The Journal of hospital infection, 1986, Volume: 7, Issue:1

    Topics: Age Factors; Animals; Anti-Bacterial Agents; Bacterial Infections; Bottle Feeding; Cross Infection;

1986
Surgical problems in amoebiasis.
    Annals of the Royal College of Surgeons of England, 1973, Volume: 52, Issue:1

    Topics: Abscess; Amebiasis; Amebicides; Anti-Bacterial Agents; Appendicitis; Colonic Diseases; Dysentery, Am

1973

Trials

19 trials available for metronidazole and Intestinal Perforation

ArticleYear
A contrast study of Dermacyn on enterocoely irrigate to control intraoperative infection.
    Minerva chirurgica, 2017, Volume: 72, Issue:2

    Topics: Abdominal Injuries; Adolescent; Adult; Aged; Anti-Infective Agents, Local; Ascitic Fluid; C-Reactive

2017
Moxifloxacin for the treatment of patients with complicated intra-abdominal infections (the AIDA Study).
    Journal of chemotherapy (Florence, Italy), 2009, Volume: 21, Issue:2

    Topics: Abdominal Abscess; Administration, Oral; Adult; Aged; Amoxicillin-Potassium Clavulanate Combination;

2009
Oral antibiotics in the management of perforated appendicitis in children.
    The American surgeon, 2002, Volume: 68, Issue:12

    Topics: Administration, Oral; Adolescent; Anti-Bacterial Agents; Anti-Infective Agents; Appendectomy; Append

2002
Septic complications after appendicectomy for perforated appendicitis. A controlled clinical trial metronidazole and topical ampicillin.
    Acta chirurgica Scandinavica, 1983, Volume: 149, Issue:5

    Topics: Adolescent; Adult; Aged; Ampicillin; Appendectomy; Appendicitis; Child; Child, Preschool; Clinical T

1983
The management of the perforated appendix: a controlled clinical trial.
    The British journal of surgery, 1982, Volume: 69, Issue:9

    Topics: Adult; Aged; Appendectomy; Appendicitis; Clinical Trials as Topic; Drug Administration Schedule; Hum

1982
Rational use of antibiotic therapy after appendicectomy.
    British medical journal, 1980, Feb-02, Volume: 280, Issue:6210

    Topics: Adolescent; Adult; Aged; Ampicillin; Appendectomy; Appendicitis; Child; Child, Preschool; Female; Ga

1980
[Antibiotic therapy of perforated appendicitis in children: comparison between the amoxicillin-clavulanic acid and the benzylpenicillin-netilmicin-metronidazole combinations].
    Pediatrie, 1993, Volume: 48, Issue:9

    Topics: Adolescent; Amoxicillin; Appendicitis; Child; Child, Preschool; Clavulanic Acids; Drug Therapy, Comb

1993
The effect of ranitidine on postoperative infectious complications following emergency colorectal surgery: a randomized, placebo-controlled, double-blind trial.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1998, Volume: 47, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cefuroxime; Colonic Diseases; Double-Blind Method; Femal

1998
Effectiveness of collagen-gentamicin implant for treatment of "dirty" abdominal wounds.
    World journal of surgery, 1999, Volume: 23, Issue:2

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Local;

1999
Can oral metronidazole substitute parenteral drug therapy in acute appendicitis? A new policy in the management of simple or complicated appendicitis with localized peritonitis: a randomized controlled clinical trial.
    The American surgeon, 1999, Volume: 65, Issue:5

    Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Anti-Infective Agents; Appendicitis; Ceftizo

1999
Piperacillin/tazobactam compared with cefuroxime/ metronidazole in the treatment of intra-abdominal infections.
    The European journal of surgery = Acta chirurgica, 1999, Volume: 165, Issue:9

    Topics: Abdominal Abscess; Appendicitis; Bacterial Infections; beta-Lactamase Inhibitors; Cefuroxime; Drug T

1999
Piperacillin/Tazobactam versus cefotaxime plus metronidazole for treatment of children with intra-abdominal infections requiring surgery.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2001, Volume: 20, Issue:9

    Topics: Abdominal Abscess; Adolescent; Appendicitis; Bacterial Infections; Cefotaxime; Child; Child, Prescho

2001
Results of a pilot trial comparing prolonged intravenous antibiotics with sequential intravenous/oral antibiotics for children with perforated appendicitis.
    Archives of surgery (Chicago, Ill. : 1960), 2001, Volume: 136, Issue:12

    Topics: Administration, Oral; Adolescent; Ampicillin; Appendicitis; Child; Child, Preschool; Clavulanic Acid

2001
Analysis of cefepime tissue penetration into human appendix.
    Pharmacotherapy, 1991, Volume: 11, Issue:5

    Topics: Adolescent; Adult; Appendectomy; Appendicitis; Appendix; Ascitic Fluid; Cefepime; Cephalosporins; Cl

1991
[General or individually calculated preventive antibiotic administration. Summary of the Magdeburg appendicitis study].
    Zentralblatt fur Chirurgie, 1991, Volume: 116, Issue:13

    Topics: Acute Disease; Adult; Ampicillin; Appendectomy; Appendicitis; Female; Humans; Infusions, Intravenous

1991
[Wound infection following appendectomy. Metronidazole vs ornidazole as single-dose prophylaxis in non-perforated appendix].
    Schweizerische medizinische Wochenschrift, 1988, Oct-01, Volume: 118, Issue:39

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Appendicitis; Child; Female; Humans; Intestinal Perforat

1988
[Antibiotic treatment of perforated appendicitis in childhood--a prospective study].
    Zeitschrift fur Kinderchirurgie : organ der Deutschen, der Schweizerischen und der Osterreichischen Gesellschaft fur Kinderchirurgie = Surgery in infancy and childhood, 1986, Volume: 41, Issue:1

    Topics: Anti-Bacterial Agents; Appendectomy; Appendicitis; Child; Clinical Trials as Topic; Drug Combination

1986
A prospective randomized study of continuous peritoneal lavage postoperatively in the treatment of purulent peritonitis.
    Surgery, gynecology & obstetrics, 1986, Volume: 163, Issue:5

    Topics: Adult; Aged; Appendicitis; Bacterial Infections; Cefuroxime; Child; Clinical Trials as Topic; Coloni

1986
[Metronidazole prophylaxis in appendectomy].
    Nederlands tijdschrift voor geneeskunde, 1986, Apr-26, Volume: 130, Issue:17

    Topics: Adolescent; Adult; Aged; Appendectomy; Appendicitis; Child; Double-Blind Method; Female; Humans; Int

1986

Other Studies

32 other studies available for metronidazole and Intestinal Perforation

ArticleYear
[A case of amebic colitis that developed after corticosteroid therapy in which perforation occurred during metronidazole treatment].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2021, Volume: 118, Issue:5

    Topics: Adrenal Cortex Hormones; Amebiasis; Dysentery, Amebic; Humans; Intestinal Perforation; Male; Metroni

2021
    BMJ case reports, 2019, Mar-20, Volume: 12, Issue:3

    Topics: Anti-Bacterial Agents; Ceftriaxone; Humans; Intestinal Perforation; Male; Metronidazole; Middle Aged

2019
Clostridium difficile bacteremia.
    Surgical infections, 2013, Volume: 14, Issue:6

    Topics: Anti-Bacterial Agents; Bacteremia; Clostridioides difficile; Clostridium Infections; Humans; Intesti

2013
Endoscopic treatment of delayed colon perforation: the enteroscopy overtube approach.
    Endoscopy, 2014, Volume: 46, Issue:6

    Topics: Adult; Aged; Anti-Infective Agents; Colonoscopy; Dissection; Female; Humans; Intestinal Mucosa; Inte

2014
Nonoperative management of perforated diverticulitis with extraluminal air is safe and effective in selected patients.
    Diseases of the colon and rectum, 2014, Volume: 57, Issue:7

    Topics: Acute Disease; Administration, Intravenous; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; C

2014
[Fulminant Clostridium difficile colitis].
    Gastroenterologia y hepatologia, 2016, Volume: 39, Issue:8

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Clostridioides difficile; Colectomy; Enterocol

2016
Cecal Perforation Associated with Clostridium difficile Infection: A Case Report.
    The Journal of emergency medicine, 2017, Volume: 52, Issue:4

    Topics: Aged; Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Colectomy; Colon; Con

2017
Spontaneous rupture of the rectum with evisceration of small intestine through the anus.
    JPMA. The Journal of the Pakistan Medical Association, 2008, Volume: 58, Issue:6

    Topics: Aged; Anal Canal; Anti-Bacterial Agents; Anti-Infective Agents; Anus Diseases; Ceftriaxone; Female;

2008
Fulminant amoebic colitis during chemotherapy for advanced gastric cancer.
    World journal of gastroenterology, 2009, Jul-21, Volume: 15, Issue:27

    Topics: Animals; Antineoplastic Agents; Antiprotozoal Agents; Dysentery, Amebic; Fatal Outcome; Humans; Inte

2009
[Complicated sigmoid tumor: perforated amebiasis].
    Medecine tropicale : revue du Corps de sante colonial, 2010, Volume: 70, Issue:4

    Topics: Antiprotozoal Agents; Colectomy; Colon, Sigmoid; Dysentery, Amebic; Humans; Intestinal Perforation;

2010
Results of a prospective, randomized, double blind comparison of the efficacy and the safety of sequential ciprofloxacin (intravenous/oral)+metronidazole (intravenous/oral) with ceftriaxone (intravenous)+metronidazole (intravenous/oral) for the treatment
    International journal of antimicrobial agents, 2003, Volume: 21, Issue:1

    Topics: Abdominal Abscess; Adult; Aged; Bacterial Infections; Ceftriaxone; Ciprofloxacin; Double-Blind Metho

2003
[Rupture of the Achilles' tendon secondary to levofloxacin].
    Gastroenterologia y hepatologia, 2003, Volume: 26, Issue:1

    Topics: Achilles Tendon; Adult; Ceftriaxone; Ciprofloxacin; Crohn Disease; Drug Therapy, Combination; Humans

2003
Acute perforative appendicitis during preoperative chemotherapy for Wilms tumor.
    Pediatric hematology and oncology, 2003, Volume: 20, Issue:2

    Topics: Abdominal Pain; Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Appendicitis; Ceftazi

2003
Effects of age on mortality and antibiotic efficacy in cecal ligation and puncture.
    Shock (Augusta, Ga.), 2003, Volume: 19, Issue:4

    Topics: Age Factors; Aging; Animals; Cecum; Ceftriaxone; Disease Susceptibility; Drug Therapy, Combination;

2003
Sonographic diagnosis of a toothpick traversing the duodenum and penetrating into the liver.
    Journal of clinical ultrasound : JCU, 2006, Volume: 34, Issue:5

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteremia; Cefoxitin; Duodenum; Follow-Up Studies; Fo

2006
Typhoid intestinal disease: 32 perforations in 1 patient.
    The Nigerian postgraduate medical journal, 2008, Volume: 15, Issue:1

    Topics: Anti-Infective Agents; Antiprotozoal Agents; Child, Preschool; Ciprofloxacin; Colectomy; Female; Gen

2008
Medical therapy of inflammatory bowel disease.
    The Medical clinics of North America, 1980, Volume: 64, Issue:6

    Topics: Acute Disease; Adjuvants, Immunologic; Anus Diseases; Azathioprine; Colitis, Ulcerative; Crohn Disea

1980
Antibiotic treatment for gangrenous and perforated appendix.
    British medical journal, 1980, Mar-15, Volume: 280, Issue:6216

    Topics: Appendicitis; Gangrene; Humans; Intestinal Perforation; Metronidazole; Surgical Wound Infection

1980
[Typhoid perforations: experiences in a surgical setting in Cameroon. Apropos of 49 cases].
    Medecine tropicale : revue du Corps de sante colonial, 1994, Volume: 54, Issue:3

    Topics: Adult; Aged; Ampicillin; Anastomosis, Surgical; Cameroon; Chloramphenicol; Colon; Combined Modality

1994
Laparoscopic management of generalized peritonitis due to perforated colonic diverticula.
    American journal of surgery, 1996, Volume: 171, Issue:4

    Topics: Adult; Aged; Anti-Bacterial Agents; Cephalosporins; Diverticulum, Colon; Female; Follow-Up Studies;

1996
Laparoscopic management of generalized peritonitis due to perforated colonic diverticula.
    American journal of surgery, 1996, Volume: 171, Issue:4

    Topics: Adult; Aged; Anti-Bacterial Agents; Cephalosporins; Diverticulum, Colon; Female; Follow-Up Studies;

1996
Laparoscopic management of generalized peritonitis due to perforated colonic diverticula.
    American journal of surgery, 1996, Volume: 171, Issue:4

    Topics: Adult; Aged; Anti-Bacterial Agents; Cephalosporins; Diverticulum, Colon; Female; Follow-Up Studies;

1996
Laparoscopic management of generalized peritonitis due to perforated colonic diverticula.
    American journal of surgery, 1996, Volume: 171, Issue:4

    Topics: Adult; Aged; Anti-Bacterial Agents; Cephalosporins; Diverticulum, Colon; Female; Follow-Up Studies;

1996
Typhoid perforation treated with and without metronidazole along with chloramphenicol, gentamycin.
    JPMA. The Journal of the Pakistan Medical Association, 1996, Volume: 46, Issue:3

    Topics: Adolescent; Child; Chloramphenicol; Drug Therapy, Combination; Female; Gentamicins; Humans; Ileal Di

1996
[Post-partum malignant amebic colitis. Apropos of a case].
    Annales de chirurgie, 1996, Volume: 50, Issue:7

    Topics: Adult; Anti-Bacterial Agents; Colectomy; Dysentery, Amebic; Female; Humans; Intestinal Perforation;

1996
Non-operative treatment of duodenal perforation secondary to blunt abdominal trauma.
    Injury, 2001, Volume: 32, Issue:6

    Topics: Adolescent; Ampicillin; Anti-Infective Agents; Duodenal Diseases; Enteral Nutrition; Female; Fluid T

2001
Metronidazole-resistant Bacteroides from untreated patient.
    Lancet (London, England), 1979, Apr-14, Volume: 1, Issue:8120

    Topics: Acute Disease; Appendicitis; Bacteroides fragilis; Child; Drug Resistance, Microbial; Humans; Intest

1979
Invasive amebiasis. I. Amebic dysentery and its complications.
    Medicine, 1977, Volume: 56, Issue:4

    Topics: Adult; Amebiasis; Amebicides; Child, Preschool; Colonic Diseases; Entamoeba histolytica; Granuloma;

1977
Typhoid perforation: further experience with end-to-side ileotransverse colostomy.
    Tropical doctor, 1990, Volume: 20, Issue:3

    Topics: Adult; Colostomy; Female; Humans; India; Intestinal Perforation; Male; Metronidazole; Postoperative

1990
Percutaneous treatment of an intrahepatic abscess caused by a penetrating duodenal ulcer.
    Journal of clinical gastroenterology, 1987, Volume: 9, Issue:5

    Topics: Combined Modality Therapy; Drainage; Duodenal Ulcer; Gentamicins; Histamine H2 Antagonists; Humans;

1987
[Long-term experience with rectal administration of metronidazole in the treatment of perforated appendicitis].
    Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti, 1988, Volume: 67, Issue:7

    Topics: Abdomen; Abscess; Adolescent; Adult; Appendicitis; Child; Female; Humans; Intestinal Perforation; Ma

1988
Retroperitoneal abscess following sclerotherapy for hemorrhoids.
    Diseases of the colon and rectum, 1985, Volume: 28, Issue:3

    Topics: Abscess; Adult; Erythromycin; Gentamicins; Hemorrhoids; Humans; Intestinal Perforation; Male; Metron

1985
[Metronidazole (Klion) in the prevention and therapy of septic complications of appendectomy].
    Orvosi hetilap, 1985, Dec-29, Volume: 126, Issue:52

    Topics: Acute Disease; Aged; Appendectomy; Humans; Intestinal Perforation; Male; Metronidazole; Middle Aged;

1985
Intestinal amebiasis. A roentgen analysis of 19 cases including 2 case reports.
    The American journal of roentgenology, radium therapy, and nuclear medicine, 1974, Volume: 122, Issue:2

    Topics: Abscess; Aged; Cecal Diseases; Colitis, Ulcerative; Colonic Diseases; Colonic Neoplasms; Diagnosis,

1974
Amoebic perforation of the colon.
    The British journal of surgery, 1974, Volume: 61, Issue:2

    Topics: Adult; Colon; Colonic Diseases; Dysentery, Amebic; Female; Humans; Intestinal Perforation; Metronida

1974