metronidazole has been researched along with Insulin Sensitivity in 4 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Soto, M | 1 |
| Herzog, C | 1 |
| Pacheco, JA | 1 |
| Fujisaka, S | 1 |
| Bullock, K | 1 |
| Clish, CB | 1 |
| Kahn, CR | 1 |
| Zarrinpar, A | 1 |
| Chaix, A | 1 |
| Xu, ZZ | 1 |
| Chang, MW | 1 |
| Marotz, CA | 1 |
| Saghatelian, A | 1 |
| Knight, R | 1 |
| Panda, S | 1 |
| Rashid Dar, N | 1 |
| Raza, N | 1 |
| Gen, R | 1 |
| Demir, M | 1 |
| Ataseven, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Nutrients Supplementation in Antidepressant Treated Depressive Disorder Patients[NCT04179006] | 120 participants (Anticipated) | Interventional | 2019-11-14 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for metronidazole and Insulin Sensitivity
| Article | Year |
|---|---|
Gut microbiota modulate neurobehavior through changes in brain insulin sensitivity and metabolism.
Topics: Animals; Anti-Bacterial Agents; Anxiety; Brain; Diet, High-Fat; Gastrointestinal Microbiome; Inflamm | 2018 |
Antibiotic-induced microbiome depletion alters metabolic homeostasis by affecting gut signaling and colonic metabolism.
Topics: Amphotericin B; Ampicillin; Animals; Anti-Bacterial Agents; Bile Acids and Salts; Blood Glucose; Bod | 2018 |
Drug induced linear IgA disease with unusual features: Koebner phenomenon, local insulin sensitivity and annular blister of the nipples.
Topics: Adult; Anti-Infective Agents; Autoimmune Diseases; Butylscopolammonium Bromide; Drug Eruptions; Huma | 2008 |
Effect of Helicobacter pylori eradication on insulin resistance, serum lipids and low-grade inflammation.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Bacterial Agents; C-Reactive Prote | 2010 |