Page last updated: 2024-10-31

metronidazole and Inguinal Hernia

metronidazole has been researched along with Inguinal Hernia in 2 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Research Excerpts

ExcerptRelevanceReference
"In a district rural hospital in Uganda, 850 surgical patients were evaluated prospectively over a 3-year period to compare the clinical efficacy of conventional postoperative penicillin therapy with single-dose ampicillin prophylaxis for hernia repair and ectopic pregnancy, and with single-dose ampicillin-metronidazole prophylaxis for hysterectomy and caesarean section."5.08Randomized study of antibiotic prophylaxis for general and gynaecological surgery from a single centre in rural Africa. ( Andreata, M; Cocozza, E; Mukasa, F; Ravera, M; Reggiori, A, 1996)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Reggiori, A1
Ravera, M1
Cocozza, E1
Andreata, M1
Mukasa, F1
Luger, A1

Trials

1 trial available for metronidazole and Inguinal Hernia

ArticleYear
Randomized study of antibiotic prophylaxis for general and gynaecological surgery from a single centre in rural Africa.
    The British journal of surgery, 1996, Volume: 83, Issue:3

    Topics: Adolescent; Adult; Aged; Ampicillin; Antibiotic Prophylaxis; Cesarean Section; Drug Therapy, Combina

1996

Other Studies

1 other study available for metronidazole and Inguinal Hernia

ArticleYear
[Syphilis diagnosis in the age of antibiotics].
    Wiener klinische Wochenschrift, 1971, Apr-09, Volume: 83, Issue:14

    Topics: Adult; Aged; Alopecia; Anti-Bacterial Agents; Balanitis; Biopsy; Child; Child, Preschool; Chloramphe

1971