metronidazole has been researched along with Infective Endocarditis in 5 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metronidazole was introduced (500mg X 3 by day)." | 1.72 | ( Boukobza, M; Duval, X; Laissy, JP; Raffoul, R, 2022) |
| "Tricuspid infective endocarditis is rare and represents five to 10% of all cases of infective endocarditis." | 1.42 | Endocarditis tricuspid sub-aigue of post abortion: report of a case. ( Codjo, LH; Dohou, SH; Houenassi, MD; Hounkponou, FA; Savi de Tove, KM, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 3 (60.00) | 2.80 |
| Authors | Studies |
|---|---|
| Park, H | 1 |
| Lee, M | 1 |
| Jeong, JS | 1 |
| Boukobza, M | 1 |
| Raffoul, R | 1 |
| Duval, X | 1 |
| Laissy, JP | 1 |
| Chaudhry, R | 1 |
| Khullar, S | 1 |
| Arif, N | 1 |
| Sagar, T | 1 |
| Meena, D | 1 |
| Kumar Chowdhury, U | 1 |
| Codjo, LH | 1 |
| Savi de Tove, KM | 1 |
| Hounkponou, FA | 1 |
| Dohou, SH | 1 |
| Houenassi, MD | 1 |
| Thadepalli, H | 1 |
1 review available for metronidazole and Infective Endocarditis
| Article | Year |
|---|---|
Animal models for anaerobic infections.
Topics: Animals; Bacteria, Anaerobic; Bacterial Infections; Bacteroides Infections; Disease Models, Animal; | 1985 |
4 other studies available for metronidazole and Infective Endocarditis
| Article | Year |
|---|---|
A case of vasculitis triggered by infective endocarditis in a patient undergoing maintenance hemodialysis: a case report.
Topics: Aged; Anti-Bacterial Agents; Clostridium Infections; Echocardiography, Transesophageal; Endocarditis | 2022 |
Topics: Abscess; Adult; Anti-Bacterial Agents; Aortic Valve; Cefotaxime; Endocarditis; Endocarditis, Bacteri | 2022 |
Clostridioides difficile from intracardiac vegetation.
Topics: Anti-Bacterial Agents; Child; Clostridioides difficile; Clostridium Infections; Endocarditis; Female | 2021 |
Endocarditis tricuspid sub-aigue of post abortion: report of a case.
Topics: Abortion, Induced; Adolescent; Cefpodoxime; Ceftizoxime; Ciprofloxacin; Echocardiography; Endocardit | 2015 |