metronidazole has been researched along with Infections, Vibrio in 5 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 2 gram single dose of metronidazole was given to ten patients suffering from nonspecific vaginitis." | 7.66 | Metronidazole in treatment of non-specific vaginitis. Clinical and microbiological findings in ten patients given 2 grams of metronidazole. ( Barlow, D; Blackwell, A; Fox, A; Phillips, I, 1983) |
| "A 2 gram single dose of metronidazole was given to ten patients suffering from nonspecific vaginitis." | 3.66 | Metronidazole in treatment of non-specific vaginitis. Clinical and microbiological findings in ten patients given 2 grams of metronidazole. ( Barlow, D; Blackwell, A; Fox, A; Phillips, I, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, JW | 1 |
| Kim, TS | 1 |
| Jung, JW | 1 |
| Park, SB | 1 |
| Lee, HJ | 1 |
| Lee, DG | 1 |
| Lee, JN | 1 |
| Lee, SH | 1 |
| Blackwell, A | 1 |
| Fox, A | 1 |
| Phillips, I | 1 |
| Barlow, D | 1 |
| Spiegel, CA | 1 |
| Eschenbach, DA | 1 |
| Amsel, R | 1 |
| Holmes, KK | 1 |
| Donta, ST | 1 |
| Pohunek, M | 1 |
| Suk, K | 1 |
5 other studies available for metronidazole and Infections, Vibrio
| Article | Year |
|---|---|
[A case of liver abscess and bacteremia caused by Vibrio cholerae non-O1].
Topics: Aged; Anti-Bacterial Agents; Bacteremia; Ceftriaxone; Humans; Liver Abscess; Male; Metronidazole; Sh | 2011 |
Metronidazole in treatment of non-specific vaginitis. Clinical and microbiological findings in ten patients given 2 grams of metronidazole.
Topics: Bacterial Infections; Drug Resistance, Microbial; Female; Follow-Up Studies; Gardnerella vaginalis; | 1983 |
Curved anaerobic bacteria in bacterial (nonspecific) vaginosis and their response to antimicrobial therapy.
Topics: Adolescent; Adult; Cefoxitin; Clindamycin; Drug Resistance, Microbial; Female; Humans; Metronidazole | 1983 |
Changing concepts of infectious diarrheas.
Topics: Acute Disease; Aged; Amebiasis; Anti-Bacterial Agents; Bacterial Infections; Clostridium Infections; | 1975 |
[Problem of Vibriofluor].
Topics: Female; Humans; Leukorrhea; Metronidazole; Vibrio Infections | 1972 |