metronidazole has been researched along with Infections, Salmonella in 13 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We report a case of Salmonella brain abscess in a patient with myasthenia gravis on chronic azathioprine therapy without any prior structural brain lesion." | 7.76 | Salmonella brain abscess in a patient on chronic azathioprine therapy for myasthenia gravis: report of an unusual case and review of literature in the postantibiotic era. ( Bollu, PC; Kumar, G; Litofsky, NS; Sahota, P; Soni, CR, 2010) |
| " We report a case of Salmonella brain abscess in a patient with myasthenia gravis on chronic azathioprine therapy without any prior structural brain lesion." | 3.76 | Salmonella brain abscess in a patient on chronic azathioprine therapy for myasthenia gravis: report of an unusual case and review of literature in the postantibiotic era. ( Bollu, PC; Kumar, G; Litofsky, NS; Sahota, P; Soni, CR, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (23.08) | 18.7374 |
| 1990's | 3 (23.08) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (53.85) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ferstl, PG | 1 |
| Reinheimer, C | 1 |
| Jozsa, K | 1 |
| Zeuzem, S | 1 |
| Kempf, VA | 1 |
| Waidmann, O | 1 |
| Grammatikos, G | 1 |
| Birczyńska, M | 1 |
| Czepiel, J | 1 |
| Pejka, K | 1 |
| Biesiada, G | 1 |
| Jędrychowski, M | 1 |
| Sobczyk-Krupiarz, I | 1 |
| Michalak, M | 1 |
| Garlicki, A | 1 |
| Apelt, N | 1 |
| Thompson, E | 1 |
| Brown, E | 1 |
| Schindel, D | 1 |
| Hélias, M | 1 |
| Planchon, J | 1 |
| Bousquet, A | 1 |
| Dubost, C | 1 |
| Lipton, G | 1 |
| Tikka, T | 1 |
| Soulsby, H | 1 |
| Keh, S | 1 |
| Steven Esworthy, R | 1 |
| Kim, BW | 1 |
| Wang, Y | 1 |
| Gao, Q | 1 |
| Doroshow, JH | 1 |
| Leto, TL | 1 |
| Chu, FF | 1 |
| Soni, CR | 1 |
| Kumar, G | 1 |
| Bollu, PC | 1 |
| Sahota, P | 1 |
| Litofsky, NS | 1 |
| Laing, RB | 1 |
| Wynn, RF | 1 |
| Leen, CL | 1 |
| Stansfield, R | 1 |
| McConkey, SJ | 1 |
| McCarthy, ND | 1 |
| Keane, CT | 1 |
| Workman, MR | 1 |
| Price, EH | 1 |
| Bullock, P | 1 |
| Hountondji, A | 1 |
| Monteiro, B | 1 |
| Savi, T | 1 |
| Diop, S | 1 |
| Donta, ST | 1 |
| Kradolfer, F | 1 |
| Jarumilinta, R | 1 |
| Sackmann, W | 1 |
1 review available for metronidazole and Infections, Salmonella
| Article | Year |
|---|---|
Prevertebral neck abscess with
Topics: Abscess; Ceftriaxone; Ciprofloxacin; Diabetes Mellitus, Type 2; Drainage; Humans; Male; Metronidazol | 2019 |
12 other studies available for metronidazole and Infections, Salmonella
| Article | Year |
|---|---|
Severe infection with multidrug-resistant
Topics: Adult; Anti-Infective Agents; beta-Lactamases; Cholangiopancreatography, Endoscopic Retrograde; Chol | 2017 |
Clostridium difficile infection in young people - 2 case reports.
Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Ceftriaxone; Clostridioides difficile; Clostridi | 2018 |
In trauma, expect the unexpected: a rare case of post-traumatic pancreatitis associated with salmonellosis and enterocolitis.
Topics: Abdomen; Adolescent; Anti-Bacterial Agents; Ceftriaxone; Clostridioides difficile; Enterocolitis, Ps | 2018 |
Topics: Anti-Bacterial Agents; Ceftriaxone; Humans; Intestinal Perforation; Male; Metronidazole; Middle Aged | 2019 |
The Gdac1 locus modifies spontaneous and Salmonella-induced colitis in mice deficient in either Gpx2 or Gpx1 gene.
Topics: Alleles; Animals; Apoptosis; Cell Proliferation; Colitis; Cyclooxygenase 2; Dysbiosis; Epithelial Ce | 2013 |
Salmonella brain abscess in a patient on chronic azathioprine therapy for myasthenia gravis: report of an unusual case and review of literature in the postantibiotic era.
Topics: Abscess; Anti-Infective Agents; Azathioprine; Brain; Ciprofloxacin; Drug Administration Schedule; Fe | 2010 |
Spontaneous Salmonella peritonitis in HIV infection.
Topics: Adult; Anti-Bacterial Agents; Bacteremia; Female; HIV Infections; Humans; Metronidazole; Peritonitis | 1995 |
Primary peritonitis due to nonenteric salmonellae.
Topics: Adolescent; Aged; Amoxicillin; Cefotaxime; Ciprofloxacin; Clavulanic Acid; Fatal Outcome; Humans; Ma | 1999 |
Salmonella meningitis and multiple cerebral abscesses in an infant.
Topics: Amoxicillin; Ampicillin; Brain Abscess; Cefotaxime; Chloramphenicol; Ciprofloxacin; Drug Therapy, Co | 1999 |
[Place of salmonellosis in gastroenteritis in Cotonou].
Topics: Adolescent; Adult; Age Factors; Ampicillin; Benin; Chloramphenicol; Female; Gastroenteritis; Humans; | 1979 |
Changing concepts of infectious diarrheas.
Topics: Acute Disease; Aged; Amebiasis; Anti-Bacterial Agents; Bacterial Infections; Clostridium Infections; | 1975 |
The amoebicidal, trichomonicidal, and antibacterial effects of niridazole in laboratory animals.
Topics: Amebiasis; Amebicides; Amoeba; Animals; Anthelmintics; Antimony; Antiprotozoal Agents; Chloroquine; | 1969 |