metronidazole has been researched along with Infections, Nematode in 8 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (62.50) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shaw, S | 1 |
| Speare, R | 1 |
| Lynn, DH | 1 |
| Yeates, G | 1 |
| Zhao, Z | 1 |
| Berger, L | 1 |
| Jakob-Hoff, R | 1 |
| Gupta, MC | 1 |
| Urrutia, JJ | 1 |
| Taylor, M | 1 |
| Pillai, G | 1 |
| Kvalsvig, JD | 1 |
| Ollé-Goig, JE | 1 |
| Recacoechea, M | 1 |
| Feeley, T | 1 |
| Fossati, C | 1 |
| Seth, D | 1 |
| Lovekar, CD | 1 |
| Knight, R | 1 |
| Schultz, MG | 1 |
| Hoskins, DW | 1 |
| Marsden, PD | 1 |
| Holmes, GK | 1 |
| Gelfand, M | 1 |
| Boyt, W | 1 |
| Mackenzie, P | 1 |
2 reviews available for metronidazole and Infections, Nematode
| Article | Year |
|---|---|
[Treatment of intestinal parasitosis].
Topics: Amphotericin B; Anthelmintics; Bithionol; Cestode Infections; Chloroquine; Humans; Intestinal Diseas | 1975 |
Intestinal parasites.
Topics: Animals; Anthelmintics; Antimony; Chloroquine; Coccidiosis; Diphyllobothriasis; Dysentery, Amebic; E | 1973 |
6 other studies available for metronidazole and Infections, Nematode
| Article | Year |
|---|---|
Nematode and ciliate nasal infection in captive archey's frogs (Leiopelma archeyi).
Topics: Animals; Animals, Zoo; Anthelmintics; Anti-Infective Agents; Anura; Ciliophora; Ciliophora Infection | 2011 |
[Effect of periodic chemotherapeutic treatment of intestinal parasites on the growth of preschool children].
Topics: Ascaridiasis; Child, Preschool; Drug Therapy, Combination; Feces; Female; Giardiasis; Growth; Guatem | 1982 |
Targeted chemotherapy for parasite infestations in rural black preschool children.
Topics: Albendazole; Antiparasitic Agents; Black or African American; Black People; Cestode Infections; Chil | 1995 |
First case of Lagochilascaris minor infection in Bolivia.
Topics: Adolescent; Anti-Bacterial Agents; Antitrichomonal Agents; Bolivia; Humans; Male; Metronidazole; Nem | 1996 |
Letter: A new chemotherapeutic property of metronidazole: effect against oxyurids in mice.
Topics: Animals; Metronidazole; Mice; Nematode Infections; Oxyuriasis | 1973 |
A study to investigate the pathogenicity of a parasite resembling Acanthocheilonema perstans.
Topics: Diethylcarbamazine; Dipetalonema; Eosinophilia; Humans; Joint Diseases; Metronidazole; Nematode Infe | 1969 |