metronidazole has been researched along with Infection, Pelvic in 5 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Avila, M | 1 |
| Funston, JR | 1 |
| Axtell, AA | 1 |
| Lentz, SE | 1 |
| Lissauer, D | 2 |
| Wilson, A | 2 |
| Daniels, J | 2 |
| Middleton, L | 2 |
| Bishop, J | 1 |
| Hewitt, C | 1 |
| Merriel, A | 2 |
| Weeks, A | 2 |
| Mhango, C | 2 |
| Mataya, R | 2 |
| Taulo, F | 2 |
| Ngalawesa, T | 2 |
| Chirwa, A | 2 |
| Mphasa, C | 2 |
| Tambala, T | 2 |
| Chiudzu, G | 2 |
| Mwalwanda, C | 2 |
| Mboma, A | 2 |
| Qureshi, R | 2 |
| Ahmed, I | 2 |
| Ismail, H | 2 |
| Gulmezoglu, M | 1 |
| Oladapo, OT | 2 |
| Mbaruku, G | 2 |
| Chibwana, J | 2 |
| Watts, G | 2 |
| Simon, B | 2 |
| Ditai, J | 2 |
| Tom, CO | 1 |
| Acam, JF | 1 |
| Ekunait, J | 2 |
| Uniza, H | 1 |
| Iyaku, M | 2 |
| Anyango, M | 1 |
| Zamora, J | 2 |
| Roberts, T | 2 |
| Goranitis, I | 2 |
| Desmond, N | 2 |
| Coomarasamy, A | 2 |
| Hewitt, CA | 1 |
| Bishop, JRB | 1 |
| Otim Tom, C | 1 |
| Acam, J | 1 |
| Unzia, H | 1 |
| Makiika, JJ | 1 |
| Bar-Zeev, S | 1 |
| Arulkumaran, S | 1 |
| Bhutta, ZA | 1 |
| Gulmezoglu, AM | 1 |
| Sheikh, Z | 1 |
| Khan, AS | 1 |
| Khan, S | 1 |
| Wang, S | 1 |
| Cunha, BA | 1 |
| Hamid, NS | 1 |
| Amato, BM | 1 |
| Feuerman, M | 1 |
| Malone, B | 1 |
2 trials available for metronidazole and Infection, Pelvic
| Article | Year |
|---|---|
Prophylactic antibiotics to reduce pelvic infection in women having miscarriage surgery - The AIMS (Antibiotics in Miscarriage Surgery) trial: study protocol for a randomized controlled trial.
Topics: Abortion, Spontaneous; Administration, Oral; Adolescent; Adult; Anti-Bacterial Agents; Antibiotic Pr | 2018 |
A Randomized Trial of Prophylactic Antibiotics for Miscarriage Surgery.
Topics: Abortion, Spontaneous; Administration, Oral; Adolescent; Adult; Africa South of the Sahara; Antibiot | 2019 |
3 other studies available for metronidazole and Infection, Pelvic
| Article | Year |
|---|---|
Preoperative Vaginal Metronidazole Decreases the Risk of Pelvic Infections After Radical Robotic Hysterectomy.
Topics: Adult; Anti-Infective Agents; Antibiotic Prophylaxis; Female; Female Urogenital Diseases; Genital Ne | 2017 |
Lingua villosa nigra.
Topics: Anti-Infective Agents; Antifungal Agents; Candidiasis; Clavulanic Acid; Female; Fluconazole; Humans; | 2011 |
Metronidazole single versus multiple daily dosing in serious intraabdominal/pelvic and diabetic foot infections.
Topics: Abdomen; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteroides fragilis; Bacteroides In | 2007 |