metronidazole has been researched along with Infarct in 3 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report an unusual presentation of pulmonary embolism (PE) where a 58-year-old man first developed symptoms of community-acquired pneumonia." | 1.48 | An unusual presentation of pulmonary embolism leading to infarction, cavitation, abscess formation and bronchopleural fistulation. ( Banerjee, A; Bennett, L; Morelli, T; Teng, E, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, C | 1 |
| Cheng, X | 1 |
| Zhong, S | 1 |
| Liu, Z | 1 |
| Liu, F | 1 |
| Lin, X | 1 |
| Zhao, Y | 1 |
| Guan, M | 1 |
| Xiao, T | 1 |
| Jolkkonen, J | 1 |
| Wang, Y | 1 |
| Zhao, C | 1 |
| Teng, E | 1 |
| Bennett, L | 1 |
| Morelli, T | 1 |
| Banerjee, A | 1 |
| Kenyon, C | 1 |
| Otto, M | 1 |
3 other studies available for metronidazole and Infarct
| Article | Year |
|---|---|
Long-term modification of gut microbiota by broad-spectrum antibiotics improves stroke outcome in rats.
Topics: Ampicillin; Animals; Anti-Bacterial Agents; Ciprofloxacin; Cytokines; Endothelin-1; Fatty Acids, Vol | 2022 |
An unusual presentation of pulmonary embolism leading to infarction, cavitation, abscess formation and bronchopleural fistulation.
Topics: Abscess; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Bronchial Fistula; Di | 2018 |
Bowel "infarction" in a postpartum patient.
Topics: Abdominal Pain; Adult; Anti-Bacterial Agents; Ceftriaxone; Enoxaparin; Entamoeba histolytica; Entamo | 2011 |